DMS-273 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description disease: carcinoma, small cell (Cell Line Ontology, CLO_0002797)
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Genes

92 genes with high or low copy number in DMS-273 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
FHL3 four and a half LIM domains 3 2.76305
MIR3659 microRNA 3659 2.76305
POU3F1 POU class 3 homeobox 1 2.76305
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 2.76305
RRAGC Ras-related GTP binding C 2.59653
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 2.59653
GJA9 gap junction protein, alpha 9, 59kDa 2.59653
MYCBP MYC binding protein 2.59653
GJA9-MYCBP GJA9-MYCBP readthrough 2.49065
AKIRIN1 akirin 1 2.49065
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) 2.49065
MIR30E microRNA 30e 2.44392
MIR30C1 microRNA 30c-1 2.44392
SLFNL1-AS1 SLFNL1 antisense RNA 1 2.39327
SLFNL1 schlafen-like 1 2.39327
SCMH1 sex comb on midleg homolog 1 (Drosophila) 2.39327
CTPS1 CTP synthase 1 2.39327
RIMS3 regulating synaptic membrane exocytosis 3 2.39327
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.39327
KIAA0754 KIAA0754 2.39327
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 2.39327
NFYC nuclear transcription factor Y, gamma 2.39327
PPIEL peptidylprolyl isomerase E-like pseudogene 2.35236
MACF1 microtubule-actin crosslinking factor 1 2.35236
ZNF684 zinc finger protein 684 2.35236
ZFP69 ZFP69 zinc finger protein 2.35236
SNORA55 small nucleolar RNA, H/ACA box 55 2.35236
ZFP69B ZFP69 zinc finger protein B 2.35236
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.35236
EXO5 exonuclease 5 2.35236
COL9A2 collagen, type IX, alpha 2 2.3178
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.3178
SMAP2 small ArfGAP2 2.3178
PPT1 palmitoyl-protein thioesterase 1 2.30944
BMP8A bone morphogenetic protein 8a 2.30944
ZMPSTE24 zinc metallopeptidase STE24 2.30944
NT5C1A 5'-nucleotidase, cytosolic IA 2.30944
TMCO2 transmembrane and coiled-coil domains 2 2.30944
HPCAL4 hippocalcin like 4 2.283
RLF rearranged L-myc fusion 2.283
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.283
MFSD2A major facilitator superfamily domain containing 2A 2.25904
SCNM1 sodium channel modifier 1 2.24845
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.24845
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 2.24845
TIPE2 TNF alpha induced protein 8 like 2 2.24845
RFX5 regulatory factor X, 5 (influences HLA class II expression) 2.24845
BMP8B bone morphogenetic protein 8b 2.24845
SELENBP1 selenium binding protein 1 2.24845
OXCT2 3-oxoacid CoA transferase 2 2.24845
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.24845
CERS2 ceramide synthase 2 2.24139
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.24139
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 2.24139
TRIT1 tRNA isopentenyltransferase 1 2.24139
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 2.24139
SETDB1 SET domain, bifurcated 1 2.24139
POGZ pogo transposable element with ZNF domain 2.24139
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.24139
ZNF687 zinc finger protein 687 2.24139
TMOD4 tropomodulin 4 (muscle) 2.24139
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 2.24139
C1ORF56 chromosome 1 open reading frame 56 2.24139
GABPB2 GA binding protein transcription factor, beta subunit 2 2.24139
CDC42SE1 CDC42 small effector 1 2.24139
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.24139
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.24139
ANXA9 annexin A9 2.2355
BNIPL BCL2/adenovirus E1B 19kD interacting protein like 2.2355
PRUNE prune exopolyphosphatase 2.2355
FAM63A family with sequence similarity 63, member A 2.2355
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.23324
ARNT aryl hydrocarbon receptor nuclear translocator 2.23324
HORMAD1 HORMA domain containing 1 2.23078
FALEC focally amplified long non-coding RNA in epithelial cancer 2.23078
CTSK cathepsin K 2.23078
ENSA endosulfine alpha 2.23078
CTSS cathepsin S 2.23078
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.23078
ECM1 extracellular matrix protein 1 2.23078
GOLPH3L golgi phosphoprotein 3-like 2.23078
ZFPM2 zinc finger protein, FOG family member 2 2.22917
MCL1 myeloid cell leukemia 1 2.22917
ADAMTSL4 ADAMTS-like 4 2.22917
MIR4257 microRNA 4257 2.22917

low copy number

Symbol Name Standardized Value
GOLGA8T golgin A8 family, member T -3.56449
ULK4P3 ULK4 pseudogene 3 -3.56449
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene -3.48261
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -3.47623
DKFZP434L187 uncharacterized LOC26082 -3.47486
LRRC37A3 leucine rich repeat containing 37, member A3 -2.87511
ARL17A ADP-ribosylation factor-like 17A -2.84936