DMS-273 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00522)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00522
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Genes

195 proteins associated with the cell line DMS-273 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
ARNT aryl hydrocarbon receptor nuclear translocator
ARPIN actin-related protein 2/3 complex inhibitor
BLMH bleomycin hydrolase
BYSL bystin-like
BZW2 basic leucine zipper and W2 domains 2
C5ORF22 chromosome 5 open reading frame 22
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CEP57 centrosomal protein 57kDa
CERS2 ceramide synthase 2
CMSS1 cms1 ribosomal small subunit homolog (yeast)
CTPS1 CTP synthase 1
CTSG cathepsin G
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAAF5 dynein, axonemal, assembly factor 5
EEF2K eukaryotic elongation factor 2 kinase
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENSA endosulfine alpha
EXOSC8 exosome component 8
FAM207A family with sequence similarity 207, member A
FILIP1L filamin A interacting protein 1-like
FTO fat mass and obesity associated
GEMIN5 gem (nuclear organelle) associated protein 5
GEMIN7 gem (nuclear organelle) associated protein 7
GEMIN8 gem (nuclear organelle) associated protein 8
GGCT gamma-glutamylcyclotransferase
GMPS guanine monphosphate synthase
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLPH3L golgi phosphoprotein 3-like
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRCT1 histidine rich carboxyl terminus 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1
MACF1 microtubule-actin crosslinking factor 1
MCL1 myeloid cell leukemia 1
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MIR513A1 microRNA 513a-1
MIX23 mitochondrial matrix import factor 23
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MYCBP MYC binding protein
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NFX1 nuclear transcription factor, X-box binding 1
NISCH nischarin
NMD3 NMD3 ribosome export adaptor
NOL7 nucleolar protein 7, 27kDa
NPM3 nucleophosmin/nucleoplasmin 3
NUCLEOLIN nucleolin multifunctional protein
NUMBL numb homolog (Drosophila)-like
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PM20D2 peptidase M20 domain containing 2
PNRC1 proline-rich nuclear receptor coactivator 1
PODXL2 podocalyxin-like 2
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPT1 palmitoyl-protein thioesterase 1
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
PUS7 pseudouridylate synthase 7 (putative)
RBM28 RNA binding motif protein 28
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RLF rearranged L-myc fusion
RPL34 ribosomal protein L34
RPS19P3 ribosomal protein S19 pseudogene 3
RRP1B ribosomal RNA processing 1B
RWDD3 RWD domain containing 3
SCNM1 sodium channel modifier 1
SETDB1 SET domain, bifurcated 1
SMAP2 small ArfGAP2
SNU13 small nuclear ribonucleoprotein 13
SRPK1 SRSF protein kinase 1
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TELO2 telomere maintenance 2
TRIT1 tRNA isopentenyltransferase 1
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae)
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSLIG3A tRNA splicing ligase complex subunit 3A
TUBA4A tubulin, alpha 4a
UCK2 uridine-cytidine kinase 2
UMPS uridine monophosphate synthetase
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
XPO5 exportin 5
ZMPSTE24 zinc metallopeptidase STE24
ZNF687 zinc finger protein 687

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ATF7 activating transcription factor 7
CADM1 cell adhesion molecule 1
CADM3 cell adhesion molecule 3
CAPN1 calpain 1, (mu/I) large subunit
CHMP6 charged multivesicular body protein 6
CNTN5 contactin 5
CPLX1 complexin 1
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DOCK6 dedicator of cytokinesis 6
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
ECHDC2 enoyl CoA hydratase domain containing 2
ERAP1 endoplasmic reticulum aminopeptidase 1
ERGIC2 ERGIC and golgi 2
ESRRA estrogen-related receptor alpha
ESYT1 extended synaptotagmin-like protein 1
ETHE1 ethylmalonic encephalopathy 1
EVPL envoplakin
GALT galactose-1-phosphate uridylyltransferase
GHDC GH3 domain containing
GIMAP7 GTPase, IMAP family member 7
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPRIN3 GPRIN family member 3
GXYLT1 glucoside xylosyltransferase 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IMPACT impact RWD domain protein
IQCA1 IQ motif containing with AAA domain 1
KIAA0100 KIAA0100
LOC100131795 uncharacterized LOC100131795
LOXL1 lysyl oxidase-like 1
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LSR lipolysis stimulated lipoprotein receptor
MFSD6 major facilitator superfamily domain containing 6
MICALL1 MICAL-like 1
MIER1 mesoderm induction early response 1, transcriptional regulator
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYOF myoferlin
NCOA2 nuclear receptor coactivator 2
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NT5C2 5'-nucleotidase, cytosolic II
OR7E7P olfactory receptor, family 7, subfamily E, member 7 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PALM3 paralemmin 3
PCDHB4 protocadherin beta 4
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLBD1 phospholipase B domain containing 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PNMT phenylethanolamine N-methyltransferase
POFUT2 protein O-fucosyltransferase 2
PPCS phosphopantothenoylcysteine synthetase
PRDX5 peroxiredoxin 5
PRR14 proline rich 14
RAB15 RAB15, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS22 regulator of G-protein signaling 22
RILPL1 Rab interacting lysosomal protein-like 1
RNF169 ring finger protein 169
RUNX2 runt-related transcription factor 2
S100A16 S100 calcium binding protein A16
SARDH sarcosine dehydrogenase
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SGPL1 sphingosine-1-phosphate lyase 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SRR serine racemase
STXBP5 syntaxin binding protein 5 (tomosyn)
SUN2 Sad1 and UNC84 domain containing 2
SYT1 synaptotagmin I
THEM6 thioesterase superfamily member 6
THRAP3 thyroid hormone receptor associated protein 3
TMEM11 transmembrane protein 11
TMEM132A transmembrane protein 132A
TXN2 thioredoxin 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UFSP2 UFM1-specific peptidase 2
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VRK2 vaccinia related kinase 2
VWA5B2 von Willebrand factor A domain containing 5B2
VWA8 von Willebrand factor A domain containing 8
WDFY1 WD repeat and FYVE domain containing 1
YBX2 Y box binding protein 2
YIPF6 Yip1 domain family, member 6
ZDHHC13 zinc finger, DHHC-type containing 13
ZIC5 Zic family member 5
ZNF384 zinc finger protein 384
ZNF608 zinc finger protein 608