DNA Damage/Telomere Stress Induced Senescence Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-2559586
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Genes

60 proteins participating in the DNA Damage/Telomere Stress Induced Senescence pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ASF1A anti-silencing function 1A histone chaperone
ATM ATM serine/threonine kinase
CABIN1 calcineurin binding protein 1
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNE1 cyclin E1
CCNE2 cyclin E2
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
EP400 E1A binding protein p400
H1-0 H1.0 linker histone
H1-1 H1.1 linker histone, cluster member
H1-2 H1.2 linker histone, cluster member
H1-3 H1.3 linker histone, cluster member
H1-4 H1.4 linker histone, cluster member
H1-5 H1.5 linker histone, cluster member
H2AB1 H2A.B variant histone 1
H2AC14 H2A clustered histone 14
H2AC18 H2A clustered histone 18
H2AC20 H2A clustered histone 20
H2AC4 H2A clustered histone 4
H2AC6 H2A clustered histone 6
H2AC7 H2A clustered histone 7
H2AJ H2A.J histone
H2AX H2A.X variant histone
H2AZ2 H2A.Z variant histone 2
H2BC1 H2B clustered histone 1
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC13 H2B clustered histone 13
H2BC14 H2B clustered histone 14
H2BC15 H2B clustered histone 15
H2BC17 H2B clustered histone 17
H2BC21 H2B clustered histone 21
H2BC26 H2B clustered histone 26
H2BC3 H2B clustered histone 3
H2BC4 H2B clustered histone 4
H2BC5 H2B clustered histone 5
H2BC9 H2B clustered histone 9
H3-4 H3.4 histone, cluster member
H4C1 H4 clustered histone 1
HIRA histone cell cycle regulator
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
KAT5 K(lysine) acetyltransferase 5
LMNB1 lamin B1
MRE11 MRE11 homolog, double strand break repair nuclease
NBN nibrin
POT1 protection of telomeres 1
RAD50 RAD50 homolog (S. cerevisiae)
RB1 retinoblastoma 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TP53 tumor protein p53
UBN1 ubinuclein 1