| Dataset | GO Molecular Function Annotations 2023 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors. (Gene Ontology, GO_0050692) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0050692 |
| Similar Terms | |
| Downloads & Tools |
3 genes performing the DNA binding domain binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
