DNA catabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. (Gene Ontology, GO_0006308)
External Link http://amigo.geneontology.org/amigo/term/GO:0006308
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Genes

20 genes participating in the DNA catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
CECR2 cat eye syndrome chromosome region, candidate 2
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DICER1 dicer 1, ribonuclease type III
DNASE1 deoxyribonuclease I
DNASE1L1 deoxyribonuclease I-like 1
DNASE1L2 deoxyribonuclease I-like 2
DNASE1L3 deoxyribonuclease I-like 3
DNASE2 deoxyribonuclease II, lysosomal
DNASE2B deoxyribonuclease II beta
ENDOG endonuclease G
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FBH1 F-box DNA helicase 1
FOXL2 forkhead box L2
ISG20 interferon stimulated exonuclease gene 20kDa
MUS81 MUS81 structure-specific endonuclease subunit
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
SETMAR SET domain and mariner transposase fusion gene
TREX1 three prime repair exonuclease 1
TREX2 three prime repair exonuclease 2