DNA polymerase III, clamp loader complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
External Link http://amigo.geneontology.org/amigo/term/GO:0043846
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Genes

656 proteins co-occuring with the DNA polymerase III, clamp loader complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
RAD17 RAD17 homolog (S. pombe) 3.536
RFC2 replication factor C (activator 1) 2, 40kDa 3.387
PCNA proliferating cell nuclear antigen 3.36
HUS1 HUS1 checkpoint homolog (S. pombe) 3.291
RAD9A RAD9 homolog A (S. pombe) 3.246
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 3.205
ATAD5 ATPase family, AAA domain containing 5 3.121
RFC5 replication factor C (activator 1) 5, 36.5kDa 3.118
RFC3 replication factor C (activator 1) 3, 38kDa 3.009
RFC4 replication factor C (activator 1) 4, 37kDa 2.953
TOPBP1 topoisomerase (DNA) II binding protein 1 2.929
ATRIP ATR interacting protein 2.891
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) 2.812
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 2.751
RAD51 RAD51 recombinase 2.712
WDHD1 WD repeat and HMG-box DNA binding protein 1 2.699
FEN1 flap structure-specific endonuclease 1 2.691
DSCC1 DNA replication and sister chromatid cohesion 1 2.668
CDC45 cell division cycle 45 2.641
CLSPN claspin 2.622
CHEK1 checkpoint kinase 1 2.567
CDC6 cell division cycle 6 2.515
EXO1 exonuclease 1 2.491
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 2.487
RAD18 RAD18 E3 ubiquitin protein ligase 2.416
POLL polymerase (DNA directed), lambda 2.392
CDT1 chromatin licensing and DNA replication factor 1 2.391
CHEK2 checkpoint kinase 2 2.388
DNA2 DNA replication helicase/nuclease 2 2.383
MCM10 minichromosome maintenance complex component 10 2.378
SSBP1 single-stranded DNA binding protein 1, mitochondrial 2.333
RAD50 RAD50 homolog (S. cerevisiae) 2.302
MSH3 mutS homolog 3 2.292
ATM ATM serine/threonine kinase 2.287
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 2.287
RAD52 RAD52 homolog (S. cerevisiae) 2.243
TENT4A terminal nucleotidyltransferase 4A 2.226
MCM4 minichromosome maintenance complex component 4 2.224
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.186
POLM polymerase (DNA directed), mu 2.177
MSH6 mutS homolog 6 2.158
ORC5 origin recognition complex, subunit 5 2.152
GINS4 GINS complex subunit 4 (Sld5 homolog) 2.148
TIPIN TIMELESS interacting protein 2.145
WRNIP1 Werner helicase interacting protein 1 2.119
DBF4 DBF4 zinc finger 2.118
REV1 REV1, polymerase (DNA directed) 2.103
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.084
MCM3 minichromosome maintenance complex component 3 2.078
MSH2 mutS homolog 2 2.075
MCM6 minichromosome maintenance complex component 6 2.075
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.074
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 2.056
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 2.048
TP53BP1 tumor protein p53 binding protein 1 2.036
MCM5 minichromosome maintenance complex component 5 2.025
MUS81 MUS81 structure-specific endonuclease subunit 2.02
MDC1 mediator of DNA-damage checkpoint 1 1.999
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.974
BRCA1 breast cancer 1, early onset 1.967
USP1 ubiquitin specific peptidase 1 1.966
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 1.958
NPTN neuroplastin 1.948
WRN Werner syndrome, RecQ helicase-like 1.94
TIMELESS timeless circadian clock 1.933
ORC3 origin recognition complex, subunit 3 1.929
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.92
WDR48 WD repeat domain 48 1.914
GINS3 GINS complex subunit 3 (Psf3 homolog) 1.912
RPA3 replication protein A3, 14kDa 1.904
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 1.903
TICRR TOPBP1-interacting checkpoint and replication regulator 1.902
ETAA1 Ewing tumor-associated antigen 1 1.896
ORC4 origin recognition complex, subunit 4 1.886
POLD2 polymerase (DNA directed), delta 2, accessory subunit 1.886
MLH1 mutL homolog 1 1.873
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.871
PRIMPOL primase and polymerase (DNA-directed) 1.865
RBBP8 retinoblastoma binding protein 8 1.86
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.855
FANCD2 Fanconi anemia, complementation group D2 1.855
ORC6 origin recognition complex, subunit 6 1.853
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.849
RMI1 RecQ mediated genome instability 1 1.846
POLR1A polymerase (RNA) I polypeptide A, 194kDa 1.842
CDC7 cell division cycle 7 1.84
FANCI Fanconi anemia, complementation group I 1.837
TOP1 topoisomerase (DNA) I 1.826
PDS5A PDS5 cohesin associated factor A 1.808
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.806
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 1.806
BRIP1 BRCA1 interacting protein C-terminal helicase 1 1.799
XPA xeroderma pigmentosum, complementation group A 1.785
POLH polymerase (DNA directed), eta 1.779
HLTF helicase-like transcription factor 1.77
NEIL1 nei endonuclease VIII-like 1 (E. coli) 1.768
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 1.765
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 1.744
FANCM Fanconi anemia, complementation group M 1.74
PIF1 PIF1 5'-to-3' DNA helicase 1.735
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.734
TLK1 tousled-like kinase 1 1.727
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 1.726
POLR1B polymerase (RNA) I polypeptide B, 128kDa 1.719
DNAH8 dynein, axonemal, heavy chain 8 1.711
ERCC1 excision repair cross-complementation group 1 1.706
BRCA2 breast cancer 2, early onset 1.704
MRC1 mannose receptor, C type 1 1.704
H2AC20 H2A clustered histone 20 1.703
H2AC19 H2A clustered histone 19 1.702
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.691
SUGP1 SURP and G patch domain containing 1 1.678
UBE2N ubiquitin-conjugating enzyme E2N 1.675
ERCC2 excision repair cross-complementation group 2 1.673
SMC3 structural maintenance of chromosomes 3 1.669
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.666
FBH1 F-box DNA helicase 1 1.666
STN1 STN1 subunit of CST complex 1.665
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.657
CRYBG1 crystallin beta-gamma domain containing 1 1.642
OGG1 8-oxoguanine DNA glycosylase 1.636
EME1 essential meiotic structure-specific endonuclease 1 1.635
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 1.63
SRSF1 serine/arginine-rich splicing factor 1 1.629
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 1.629
ZRANB3 zinc finger, RAN-binding domain containing 3 1.625
H2AX H2A.X variant histone 1.624
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.621
CRB2 crumbs family member 2 1.614
LAMC3 laminin, gamma 3 1.607
TBX22 T-box 22 1.599
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 1.598
UBE2I ubiquitin-conjugating enzyme E2I 1.598
RAD9B RAD9 homolog B (S. pombe) 1.597
TP53 tumor protein p53 1.588
PNKP polynucleotide kinase 3'-phosphatase 1.587
GP5 glycoprotein V (platelet) 1.585
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 1.581
TDG thymine-DNA glycosylase 1.581
POLI polymerase (DNA directed) iota 1.579
APTX aprataxin 1.553
RNASEH2A ribonuclease H2, subunit A 1.543
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.543
RTEL1 regulator of telomere elongation helicase 1 1.539
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 1.532
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 1.532
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 1.529
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.525
MUTYH mutY homolog 1.524
RECQL RecQ helicase-like 1.508
RAD54B RAD54 homolog B (S. cerevisiae) 1.507
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 1.504
MCM9 minichromosome maintenance complex component 9 1.503
MLH3 mutL homolog 3 1.503
CDC25A cell division cycle 25A 1.492
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 1.491
TOP3A topoisomerase (DNA) III alpha 1.49
TDP1 tyrosyl-DNA phosphodiesterase 1 1.488
NIPBL Nipped-B homolog (Drosophila) 1.487
SLX4 SLX4 structure-specific endonuclease subunit 1.487
CDK1 cyclin-dependent kinase 1 1.479
WAPL WAPL cohesin release factor 1.475
UNG uracil-DNA glycosylase 1.475
GEN1 GEN1 Holliday junction 5' flap endonuclease 1.474
NBPF4 neuroblastoma breakpoint family, member 4 1.473
SPRTN SprT-like N-terminal domain 1.471
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.469
CDK2 cyclin-dependent kinase 2 1.467
TOP2A topoisomerase (DNA) II alpha 170kDa 1.467
H3-7 H3.7 histone (putative) 1.452
FAN1 FANCD2/FANCI-associated nuclease 1 1.452
H3C13 H3 clustered histone 13 1.451
H3-5 H3.5 histone 1.451
H3-4 H3.4 histone, cluster member 1.45
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 1.449
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.449
PIAS2 protein inhibitor of activated STAT, 2 1.448
H3-3B H3.3 histone B 1.448
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 1.448
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.446
NTHL1 nth endonuclease III-like 1 (E. coli) 1.441
SMC5 structural maintenance of chromosomes 5 1.422
HUS1B HUS1 checkpoint homolog b (S. pombe) 1.41
CHAF1A chromatin assembly factor 1, subunit A (p150) 1.405
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.4
XPC xeroderma pigmentosum, complementation group C 1.391
H2BC21 H2B clustered histone 21 1.388
RUVBL1 RuvB-like AAA ATPase 1 1.384
FAAP24 FA core complex associated protein 24 1.37
ERCC3 excision repair cross-complementation group 3 1.368
MMS22L MMS22-like, DNA repair protein 1.368
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.367
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.361
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 1.351
RRAD Ras-related associated with diabetes 1.345
RECQL5 RecQ protein-like 5 1.344
RFWD3 ring finger and WD repeat domain 3 1.34
RAD21 RAD21 homolog (S. pombe) 1.335
NHEJ1 nonhomologous end-joining factor 1 1.334
PARP2 poly (ADP-ribose) polymerase 2 1.333
POLK polymerase (DNA directed) kappa 1.332
PARP1 poly (ADP-ribose) polymerase 1 1.33
RAD23B RAD23 homolog B (S. cerevisiae) 1.325
ASF1A anti-silencing function 1A histone chaperone 1.324
HELQ helicase, POLQ-like 1.323
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 1.319
MMUT methylmalonyl-CoA mutase 1.318
PALB2 partner and localizer of BRCA2 1.318
NEIL2 nei endonuclease VIII-like 2 (E. coli) 1.317
FAM111A family with sequence similarity 111, member A 1.311
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.305
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 1.304
TONSL tonsoku-like, DNA repair protein 1.297
FANCE Fanconi anemia, complementation group E 1.297
CDC5L cell division cycle 5-like 1.296
MCM8 minichromosome maintenance complex component 8 1.295
LIG4 ligase IV, DNA, ATP-dependent 1.295
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.289
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 1.287
MAU2 MAU2 sister chromatid cohesion factor 1.283
PCLAF PCNA clamp associated factor 1.283
FBF1 Fas (TNFRSF6) binding factor 1 1.283
CCNA2 cyclin A2 1.279
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 1.274
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.272
PMEPA1 prostate transmembrane protein, androgen induced 1 1.267
DDB1 damage-specific DNA binding protein 1, 127kDa 1.26
SSRP1 structure specific recognition protein 1 1.257
VCP valosin containing protein 1.255
ERCC6 excision repair cross-complementation group 6 1.254
RMI2 RecQ mediated genome instability 2 1.251
FANCA Fanconi anemia, complementation group A 1.247
SIVA1 SIVA1, apoptosis-inducing factor 1.242
HROB homologous recombination factor with OB-fold 1.235
TXN2 thioredoxin 2 1.231
BLM Bloom syndrome, RecQ helicase-like 1.231
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.231
RAD51AP1 RAD51 associated protein 1 1.226
RAD51C RAD51 paralog C 1.226
TOR1AIP2 torsin A interacting protein 2 1.225
YME1L1 YME1-like 1 ATPase 1.224
MCMBP minichromosome maintenance complex binding protein 1.223
DCLRE1A DNA cross-link repair 1A 1.222
SUMO1 small ubiquitin-like modifier 1 1.219
NEIL3 nei endonuclease VIII-like 3 (E. coli) 1.217
SPO11 SPO11 meiotic protein covalently bound to DSB 1.212
UHRF1 ubiquitin-like with PHD and ring finger domains 1 1.204
TOR2A torsin family 2, member A 1.196
UIMC1 ubiquitin interaction motif containing 1 1.183
PLK1 polo-like kinase 1 1.178
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.175
RECQL4 RecQ protein-like 4 1.172
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 1.171
MSH4 mutS homolog 4 1.167
RUVBL2 RuvB-like AAA ATPase 2 1.166
WEE1 WEE1 G2 checkpoint kinase 1.166
CCNA1 cyclin A1 1.163
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.162
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.154
CRBN cereblon 1.154
ASF1B anti-silencing function 1B histone chaperone 1.153
POLN polymerase (DNA directed) nu 1.149
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 1.147
ARTN artemin 1.145
ERCC4 excision repair cross-complementation group 4 1.144
PPP4R3B protein phosphatase 4 regulatory subunit 3B 1.142
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 1.141
FANCL Fanconi anemia, complementation group L 1.138
NAP1L1 nucleosome assembly protein 1-like 1 1.136
UBE2K ubiquitin-conjugating enzyme E2K 1.135
ERRFI1 ERBB receptor feedback inhibitor 1 1.131
UBL3 ubiquitin-like 3 1.131
MRE11 MRE11 homolog, double strand break repair nuclease 1.127
SETX senataxin 1.124
CDPF1 cysteine-rich, DPF motif domain containing 1 1.117
TOP2B topoisomerase (DNA) II beta 180kDa 1.116
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.116
CD36 CD36 molecule (thrombospondin receptor) 1.113
DDB2 damage-specific DNA binding protein 2, 48kDa 1.112
FAAP100 FA core complex associated protein 100 1.109
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 1.092
RNF4 ring finger protein 4 1.088
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 1.082
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.079
PPP4C protein phosphatase 4, catalytic subunit 1.075
PURB purine-rich element binding protein B 1.073
SMC6 structural maintenance of chromosomes 6 1.071
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.067
CDC25C cell division cycle 25C 1.067
DUT deoxyuridine triphosphatase 1.065
OR10A7 olfactory receptor, family 10, subfamily A, member 7 1.063
WWOX WW domain containing oxidoreductase 1.057
NEK1 NIMA-related kinase 1 1.046
FSBP fibrinogen silencer binding protein 1.045
BARD1 BRCA1 associated RING domain 1 1.043
RNASEH2B ribonuclease H2, subunit B 1.035
ATMIN ATM interactor 1.033
MPG N-methylpurine-DNA glycosylase 1.021
H4C7 H4 clustered histone 7 1.02
PAXX PAXX non-homologous end joining factor 1.018
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 1.018
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.004
TTK TTK protein kinase 1.002
H4C15 H4 clustered histone 15 1.002
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 1.0
FHIT fragile histidine triad 0.998
PHGDH phosphoglycerate dehydrogenase 0.995
NOL7 nucleolar protein 7, 27kDa 0.994
HDAC1 histone deacetylase 1 0.991
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.988
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.985
SHISA3 shisa family member 3 0.984
ZNF829 zinc finger protein 829 0.982
FANCG Fanconi anemia, complementation group G 0.98
CDCA5 cell division cycle associated 5 0.977
KAT5 K(lysine) acetyltransferase 5 0.977
E2F1 E2F transcription factor 1 0.976
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.974
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.968
RCC1 regulator of chromosome condensation 1 0.967
UBE2T ubiquitin-conjugating enzyme E2T 0.966
FAAP20 FA core complex associated protein 20 0.966
SIRT2 sirtuin 2 0.966
DPH5 diphthamide biosynthesis 5 0.964
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.962
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.96
CUL4A cullin 4A 0.96
FANCC Fanconi anemia, complementation group C 0.957
USP20 ubiquitin specific peptidase 20 0.956
PARG poly (ADP-ribose) glycohydrolase 0.954
CCNB1 cyclin B1 0.953
SEPTIN7 septin 7 0.952
NABP2 nucleic acid binding protein 2 0.948
CHD7 chromodomain helicase DNA binding protein 7 0.948
SCAI suppressor of cancer cell invasion 0.945
FOXN2 forkhead box N2 0.942
RNF169 ring finger protein 169 0.939
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.939
SP100 SP100 nuclear antigen 0.939
H2BC1 H2B clustered histone 1 0.938
CDC20 cell division cycle 20 0.937
CDC25B cell division cycle 25B 0.936
MDN1 MDN1, midasin homolog (yeast) 0.932
ELP4 elongator acetyltransferase complex subunit 4 0.931
DPH2 DPH2 homolog (S. cerevisiae) 0.929
RAD54L RAD54-like (S. cerevisiae) 0.928
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.923
RNASEH1 ribonuclease H1 0.921
SHISA2 shisa family member 2 0.919
H2BK1 H2B.K variant histone 1 0.916
H2BW1 H2B.W histone 1 0.914
H2BC12L H2B clustered histone 12 like 0.914
H2BW2 H2B.W histone 2 0.914
H2BC13 H2B clustered histone 13 0.912
KMT5A lysine methyltransferase 5A 0.912
ENDOV endonuclease V 0.911
H2BC18 H2B clustered histone 18 0.911
H2BC17 H2B clustered histone 17 0.91
H2BC14 H2B clustered histone 14 0.91
H2BC26 H2B clustered histone 26 0.91
H2BC9 H2B clustered histone 9 0.91
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.909
H2BC15 H2B clustered histone 15 0.906
ADCY10 adenylate cyclase 10 (soluble) 0.905
H2BC3 H2B clustered histone 3 0.905
H2BC11 H2B clustered histone 11 0.904
LGALS4 lectin, galactoside-binding, soluble, 4 0.902
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 0.902
H2BC12 H2B clustered histone 12 0.901
MPLKIP M-phase specific PLK1 interacting protein 0.901
DIAPH2 diaphanous-related formin 2 0.896
H2BC4 H2B clustered histone 4 0.894
RRM1 ribonucleotide reductase M1 0.894
H2BC5 H2B clustered histone 5 0.89
CCNL2 cyclin L2 0.886
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.885
MAPK1 mitogen-activated protein kinase 1 0.885
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component 0.882
MMP11 matrix metallopeptidase 11 0.881
CINP cyclin-dependent kinase 2 interacting protein 0.878
DNLZ DNL-type zinc finger 0.875
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.87
SENP6 SUMO1/sentrin specific peptidase 6 0.869
ADARB1 adenosine deaminase, RNA-specific, B1 0.869
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 0.865
RPL11 ribosomal protein L11 0.864
TELO2 telomere maintenance 2 0.864
BRAT1 BRCA1-associated ATM activator 1 0.863
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.857
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.856
GALK1 galactokinase 1 0.856
BRD4 bromodomain containing 4 0.855
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.854
TCEA1 transcription elongation factor A (SII), 1 0.854
FANCB Fanconi anemia, complementation group B 0.853
CNOT11 CCR4-NOT transcription complex, subunit 11 0.853
PEX6 peroxisomal biogenesis factor 6 0.85
GPN1 GPN-loop GTPase 1 0.847
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.847
GATAD2B GATA zinc finger domain containing 2B 0.845
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.844
AURKB aurora kinase B 0.843
TRRAP transformation/transcription domain-associated protein 0.843
TLK2 tousled-like kinase 2 0.842
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 0.841
GTF2B general transcription factor IIB 0.835
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.829
RRM2 ribonucleotide reductase M2 0.826
HSPE1 heat shock 10kDa protein 1 0.822
APLF aprataxin and PNKP like factor 0.821
TOP1MT topoisomerase (DNA) I, mitochondrial 0.819
GP2 glycoprotein 2 (zymogen granule membrane) 0.818
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 0.811
UBA2 ubiquitin-like modifier activating enzyme 2 0.809
HID1 HID1 domain containing 0.809
C6ORF89 chromosome 6 open reading frame 89 0.808
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.808
CASS4 Cas scaffolding protein family member 4 0.808
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.805
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.803
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.802
TECRL trans-2,3-enoyl-CoA reductase-like 0.802
EME2 essential meiotic structure-specific endonuclease subunit 2 0.8
H1-0 H1.0 linker histone 0.794
SMC1A structural maintenance of chromosomes 1A 0.792
NOP58 NOP58 ribonucleoprotein 0.79
FBXW10 F-box and WD repeat domain containing 10 0.79
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.788
EP300 E1A binding protein p300 0.785
RNF113A ring finger protein 113A 0.784
CLMP CXADR-like membrane protein 0.784
CDKN2A cyclin-dependent kinase inhibitor 2A 0.783
PHAX phosphorylated adaptor for RNA export 0.78
RAD51B RAD51 paralog B 0.779
TDP2 tyrosyl-DNA phosphodiesterase 2 0.779
HELLS helicase, lymphoid-specific 0.778
KAT2A K(lysine) acetyltransferase 2A 0.778
CETN2 centrin, EF-hand protein, 2 0.777
TCHP trichoplein, keratin filament binding 0.777
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.777
PTCH2 patched 2 0.775
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.773
CHD4 chromodomain helicase DNA binding protein 4 0.773
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.77
MGMT O-6-methylguanine-DNA methyltransferase 0.769
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.768
DOT1L DOT1-like histone H3K79 methyltransferase 0.767
MYSM1 Myb-like, SWIRM and MPN domains 1 0.764
DCTD dCMP deaminase 0.763
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.76
TBL1X transducin (beta)-like 1X-linked 0.76
HDAC2 histone deacetylase 2 0.76
PDS5B PDS5 cohesin associated factor B 0.758
GTPBP1 GTP binding protein 1 0.757
SMC1B structural maintenance of chromosomes 1B 0.757
KAT2B K(lysine) acetyltransferase 2B 0.754
FANCF Fanconi anemia, complementation group F 0.754
POT1 protection of telomeres 1 0.753
HDAC8 histone deacetylase 8 0.75
TOR1A torsin family 1, member A (torsin A) 0.749
SLC39A1 solute carrier family 39 (zinc transporter), member 1 0.747
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.744
NOP56 NOP56 ribonucleoprotein 0.743
H2AZ1 H2A.Z variant histone 1 0.743
NAP1L4 nucleosome assembly protein 1-like 4 0.743
RNF2 ring finger protein 2 0.74
SHISA9 shisa family member 9 0.74
TCEA2 transcription elongation factor A (SII), 2 0.739
MCPH1 microcephalin 1 0.734
CFAP20 cilia and flagella associated protein 20 0.734
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.732
TCEA3 transcription elongation factor A (SII), 3 0.731
SIRT1 sirtuin 1 0.73
HSPB6 heat shock protein, alpha-crystallin-related, B6 0.73
INTS3 integrator complex subunit 3 0.728
NCOA4 nuclear receptor coactivator 4 0.725
SRFBP1 serum response factor binding protein 1 0.725
TYMS thymidylate synthetase 0.724
HAPLN1 hyaluronan and proteoglycan link protein 1 0.723
CLSTN1 calsyntenin 1 0.722
GP9 glycoprotein IX (platelet) 0.721
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.721
ZSCAN5A zinc finger and SCAN domain containing 5A 0.719
EIF4A3 eukaryotic translation initiation factor 4A3 0.717
ACOD1 aconitate decarboxylase 1 0.717
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.711
TJAP1 tight junction associated protein 1 (peripheral) 0.71
FAM83A family with sequence similarity 83, member A 0.705
SUMO2 small ubiquitin-like modifier 2 0.705
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.703
MTUS1 microtubule associated tumor suppressor 1 0.7
SP9 Sp9 transcription factor 0.698
TWNK twinkle mtDNA helicase 0.697
MSH5 mutS homolog 5 0.696
RPA4 replication protein A4, 30kDa 0.692
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.689
H3C7 H3 clustered histone 7 0.688
HDAC3 histone deacetylase 3 0.684
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 0.68
F8A1 coagulation factor VIII-associated 1 0.68
PXDNL peroxidasin-like 0.67
IPO4 importin 4 0.67
TOP3B topoisomerase (DNA) III beta 0.67
PXDN peroxidasin 0.668
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.668
GTF2H5 general transcription factor IIH, polypeptide 5 0.667
PACC1 proton activated chloride channel 1 0.665
CDC27 cell division cycle 27 0.664
REC114 REC114 meiotic recombination protein 0.664
CDKN3 cyclin-dependent kinase inhibitor 3 0.662
POTEF POTE ankyrin domain family, member F 0.66
HORMAD1 HORMA domain containing 1 0.659
INIP INTS3 and NABP interacting protein 0.657
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.657
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.655
UBA1 ubiquitin-like modifier activating enzyme 1 0.653
YBX1 Y box binding protein 1 0.652
H2AZ2 H2A.Z variant histone 2 0.65
SHLD1 shieldin complex subunit 1 0.647
TPTE transmembrane phosphatase with tensin homology 0.64
MAPK15 mitogen-activated protein kinase 15 0.64
EXD2 exonuclease 3'-5' domain containing 2 0.639
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.638
SPNS1 spinster homolog 1 (Drosophila) 0.637
TBP TATA box binding protein 0.634
UBE2S ubiquitin-conjugating enzyme E2S 0.634
SPIDR scaffolding protein involved in DNA repair 0.631
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.631
ASCC1 activating signal cointegrator 1 complex subunit 1 0.631
ASCC3 activating signal cointegrator 1 complex subunit 3 0.628
EP400 E1A binding protein p400 0.627
ZNF569 zinc finger protein 569 0.627
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.627
SARS1 seryl-tRNA synthetase 1 0.626
SYCE1L synaptonemal complex central element protein 1-like 0.625
PRPF19 pre-mRNA processing factor 19 0.625
CCDC82 coiled-coil domain containing 82 0.624
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.624
HORMAD2 HORMA domain containing 2 0.623
ASPH aspartate beta-hydroxylase 0.622
KDM4D lysine (K)-specific demethylase 4D 0.622
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.621
LINS1 lines homolog 1 0.621
SETDB1 SET domain, bifurcated 1 0.619
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.618
SPAST spastin 0.618
ACRV1 acrosomal vesicle protein 1 0.617
CTBP1 C-terminal binding protein 1 0.616
SARS2 seryl-tRNA synthetase 2, mitochondrial 0.615
AURKA aurora kinase A 0.615
ZBTB1 zinc finger and BTB domain containing 1 0.613
DIAPH3 diaphanous-related formin 3 0.613
NRDC nardilysin convertase 0.611
PARP3 poly (ADP-ribose) polymerase family, member 3 0.61
PIAS4 protein inhibitor of activated STAT, 4 0.609
RPAIN RPA interacting protein 0.608
BABAM1 BRISC and BRCA1 A complex member 1 0.607
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.607
KANSL1 KAT8 regulatory NSL complex subunit 1 0.604
MYRF myelin regulatory factor 0.601
CDK4 cyclin-dependent kinase 4 0.6
PHF20 PHD finger protein 20 0.599
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 0.599
SIX1 SIX homeobox 1 0.598
SWI5 SWI5 recombination repair homolog (yeast) 0.596
ASCC2 activating signal cointegrator 1 complex subunit 2 0.595
UBD ubiquitin D 0.594
ERCC8 excision repair cross-complementation group 8 0.592
ZWINT ZW10 interacting kinetochore protein 0.592
CCNE2 cyclin E2 0.591
SPATA46 spermatogenesis associated 46 0.588
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.587
UBE2A ubiquitin-conjugating enzyme E2A 0.586
DAXX death-domain associated protein 0.585
LRRC14 leucine rich repeat containing 14 0.584
PHF2 PHD finger protein 2 0.582
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.582
ISOC2 isochorismatase domain containing 2 0.581
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.581
MBD4 methyl-CpG binding domain protein 4 0.58
NMT1 N-myristoyltransferase 1 0.578
PYDC1 PYD (pyrin domain) containing 1 0.576
TCP1 t-complex 1 0.574
ZCCHC3 zinc finger, CCHC domain containing 3 0.573
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.573
PSMC3IP PSMC3 interacting protein 0.573
CCND1 cyclin D1 0.573
ZNF544 zinc finger protein 544 0.573
ZNF763 zinc finger protein 763 0.571
ZNF44 zinc finger protein 44 0.571
ZNF501 zinc finger protein 501 0.571
ZNF629 zinc finger protein 629 0.571
ZNF436 zinc finger protein 436 0.569
DLL3 delta-like 3 (Drosophila) 0.568
PIH1D1 PIH1 domain containing 1 0.567
HMHB1 histocompatibility (minor) HB-1 0.565
YBX2 Y box binding protein 2 0.563
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 0.563
SF3A3 splicing factor 3a, subunit 3, 60kDa 0.562
CD200 CD200 molecule 0.561
TTC1 tetratricopeptide repeat domain 1 0.559
CD151 CD151 molecule (Raph blood group) 0.556
ZNF280C zinc finger protein 280C 0.556
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 0.555
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.553
STAG2 stromal antigen 2 0.552
CCNE1 cyclin E1 0.552
SKIC2 SKI2 subunit of superkiller complex 0.55
DARS1 aspartyl-tRNA synthetase 1 0.548
POU3F1 POU class 3 homeobox 1 0.548
BABAM2 BRISC and BRCA1 A complex member 2 0.542
SMG7 SMG7 nonsense mediated mRNA decay factor 0.541
ZNF3 zinc finger protein 3 0.54
SLC25A46 solute carrier family 25, member 46 0.539
E2F4 E2F transcription factor 4, p107/p130-binding 0.539
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.536
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.535
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.535
CCDC90B coiled-coil domain containing 90B 0.535
MEPCE methylphosphate capping enzyme 0.532
PIAS1 protein inhibitor of activated STAT, 1 0.531
WIZ widely interspaced zinc finger motifs 0.53
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 0.53
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.529
ING5 inhibitor of growth family, member 5 0.528
UBA3 ubiquitin-like modifier activating enzyme 3 0.528
NEK11 NIMA-related kinase 11 0.525
PTTG1 pituitary tumor-transforming 1 0.525
CCKAR cholecystokinin A receptor 0.52
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.52
MCM7 minichromosome maintenance complex component 7 0.519
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 0.518
LRR1 leucine rich repeat protein 1 0.518
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 0.517
CIAO3 cytosolic iron-sulfur assembly component 3 0.516
TMC6 transmembrane channel-like 6 0.515
DNTT DNA nucleotidylexotransferase 0.514
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.513
CUL4B cullin 4B 0.512
ZUP1 zinc finger containing ubiquitin peptidase 1 0.512
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 0.512
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.511
TOR4A torsin family 4, member A 0.509
CSNK2B casein kinase 2, beta polypeptide 0.509
LMNB1 lamin B1 0.509
PLS1 plastin 1 0.508
CLCF1 cardiotrophin-like cytokine factor 1 0.507
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.507
HMGXB3 HMG box domain containing 3 0.506
AVIL advillin 0.505
SMG5 SMG5 nonsense mediated mRNA decay factor 0.505
CLPS colipase, pancreatic 0.504
RBBP4 retinoblastoma binding protein 4 0.503
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 0.503
VWA1 von Willebrand factor A domain containing 1 0.502
BIN2 bridging integrator 2 0.5