| Dataset | Reactome Pathways 2014 |
| Category | structural or functional annotations |
| Type | pathway |
| Description | The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. (Gene Ontology, GO_0006270) |
| External Link | http://www.reactome.org/PathwayBrowser/#/R-HSA-68952 |
| Similar Terms | |
| Downloads & Tools |
6 proteins participating in the DNA replication initiation pathway from the Reactome Pathways dataset.
| Symbol | Name |
|---|---|
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
