DNA replication termination region Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks. (Gene Ontology, GO_0097047)
External Link http://amigo.geneontology.org/amigo/term/GO:0097047
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Genes

311 proteins co-occuring with the DNA replication termination region cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
SEC16A SEC16 homolog A (S. cerevisiae) 2.889
SEC13 SEC13 homolog (S. cerevisiae) 2.528
PREB prolactin regulatory element binding 2.422
SEC24B SEC24 family member B 2.312
SEC16B SEC16 homolog B (S. cerevisiae) 2.294
PER1 period circadian clock 1 2.052
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.05
LMAN1 lectin, mannose-binding, 1 1.998
SEC24C SEC24 family member C 1.967
RAB1A RAB1A, member RAS oncogene family 1.865
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.766
USO1 USO1 vesicle transport factor 1.76
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.749
MIA3 melanoma inhibitory activity family, member 3 1.722
NALF2 NALCN channel auxiliary factor 2 1.697
STX5 syntaxin 5 1.68
TEF thyrotrophic embryonic factor 1.672
MEA1 male-enhanced antigen 1 1.584
EAPP E2F-associated phosphoprotein 1.552
TRAPPC2 trafficking protein particle complex 2 1.546
SAR1A secretion associated, Ras related GTPase 1A 1.543
SEC24D SEC24 family member D 1.538
SEC24A SEC24 family member A 1.524
GORASP1 golgi reassembly stacking protein 1, 65kDa 1.506
TAMALIN trafficking regulator and scaffold protein tamalin 1.501
GOLGB1 golgin B1 1.485
TM9SF3 transmembrane 9 superfamily member 3 1.48
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 1.48
B4GAT1 beta-1,4-glucuronyltransferase 1 1.47
SEC63 SEC63 homolog (S. cerevisiae) 1.465
MTFR2 mitochondrial fission regulator 2 1.464
CFAP73 cilia and flagella associated protein 73 1.456
RER1 retention in endoplasmic reticulum sorting receptor 1 1.451
PTGES2 prostaglandin E synthase 2 1.448
RNF183 ring finger protein 183 1.433
COG3 component of oligomeric golgi complex 3 1.385
SEC31A SEC31 homolog A (S. cerevisiae) 1.378
SAMD8 sterile alpha motif domain containing 8 1.367
CERT1 ceramide transporter 1 1.364
NSF N-ethylmaleimide-sensitive factor 1.358
TPR translocated promoter region, nuclear basket protein 1.351
TM9SF4 transmembrane 9 superfamily protein member 4 1.349
RAB11A RAB11A, member RAS oncogene family 1.33
TFG TRK-fused gene 1.327
KLHL12 kelch-like family member 12 1.322
RABIF RAB interacting factor 1.321
GOLGA2 golgin A2 1.304
WARS1 tryptophanyl-tRNA synthetase 1 1.275
STX18 syntaxin 18 1.268
TMED9 transmembrane emp24 protein transport domain containing 9 1.259
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 1.257
ERAS ES cell expressed Ras 1.254
BMP8A bone morphogenetic protein 8a 1.24
TTC7A tetratricopeptide repeat domain 7A 1.239
POGLUT1 protein O-glucosyltransferase 1 1.23
SEC31B SEC31 homolog B (S. cerevisiae) 1.226
SEC23A Sec23 homolog A (S. cerevisiae) 1.207
LXN latexin 1.196
GOLGA8B golgin A8 family, member B 1.194
CYTH1 cytohesin 1 1.189
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.189
RAB1B RAB1B, member RAS oncogene family 1.185
CKAP5 cytoskeleton associated protein 5 1.183
ARF1 ADP-ribosylation factor 1 1.176
COG2 component of oligomeric golgi complex 2 1.171
TES testin LIM domain protein 1.157
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 1.157
RAB6A RAB6A, member RAS oncogene family 1.155
SAR1B secretion associated, Ras related GTPase 1B 1.146
BLZF1 basic leucine zipper nuclear factor 1 1.135
KRTCAP2 keratinocyte associated protein 2 1.123
TRAPPC3 trafficking protein particle complex 3 1.12
BMP8B bone morphogenetic protein 8b 1.111
CANX calnexin 1.105
ERP44 endoplasmic reticulum protein 44 1.1
FAT2 FAT atypical cadherin 2 1.092
MTNR1A melatonin receptor 1A 1.085
CUX1 cut-like homeobox 1 1.077
TMED2 transmembrane emp24 domain trafficking protein 2 1.076
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 1.076
RPN2 ribophorin II 1.071
RAB5A RAB5A, member RAS oncogene family 1.054
GPER1 G protein-coupled estrogen receptor 1 1.053
ZNF787 zinc finger protein 787 1.051
SLC35F6 solute carrier family 35, member F6 1.047
GOSR2 golgi SNAP receptor complex member 2 1.04
MAPK15 mitogen-activated protein kinase 15 1.034
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 1.032
SCFD1 sec1 family domain containing 1 1.032
TRAPPC5 trafficking protein particle complex 5 1.031
MOGS mannosyl-oligosaccharide glucosidase 1.03
RBM8A RNA binding motif protein 8A 1.027
VARS1 valyl-tRNA synthetase 1 1.015
NDP Norrie disease (pseudoglioma) 1.013
RGPD8 RANBP2-like and GRIP domain containing 8 1.013
COPB1 coatomer protein complex, subunit beta 1 1.013
TRAPPC6A trafficking protein particle complex 6A 1.012
TRAPPC1 trafficking protein particle complex 1 1.008
YIPF5 Yip1 domain family, member 5 1.003
ESR1 estrogen receptor 1 0.999
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.999
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.995
BET1 Bet1 golgi vesicular membrane trafficking protein 0.988
ZNF135 zinc finger protein 135 0.987
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.987
SGMS1 sphingomyelin synthase 1 0.982
RHOXF1 Rhox homeobox family, member 1 0.98
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.963
SEC62 SEC62 homolog (S. cerevisiae) 0.957
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.954
F5 coagulation factor V (proaccelerin, labile factor) 0.951
CWC15 CWC15 spliceosome-associated protein 0.932
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 0.923
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.921
SYNGAP1 synaptic Ras GTPase activating protein 1 0.918
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.91
JAKMIP3 Janus kinase and microtubule interacting protein 3 0.907
ZNF460 zinc finger protein 460 0.906
TRAPPC4 trafficking protein particle complex 4 0.905
COG5 component of oligomeric golgi complex 5 0.894
FLII flightless I homolog (Drosophila) 0.894
RINT1 RAD50 interactor 1 0.889
FHIP1B FHF complex subunit HOOK interacting protein 1B 0.882
ARSD arylsulfatase D 0.875
TRIM17 tripartite motif containing 17 0.872
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.871
PEG10 paternally expressed 10 0.869
CBLN1 cerebellin 1 precursor 0.868
EXOC7 exocyst complex component 7 0.862
KIF25 kinesin family member 25 0.853
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.848
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.846
CD53 CD53 molecule 0.845
RAB2A RAB2A, member RAS oncogene family 0.843
ETV5 ets variant 5 0.832
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.831
LGALS4 lectin, galactoside-binding, soluble, 4 0.828
CTTNBP2 cortactin binding protein 2 0.825
TGFA transforming growth factor, alpha 0.82
TLCD3B TLC domain containing 3B 0.817
TRAPPC10 trafficking protein particle complex 10 0.813
RAP1B RAP1B, member of RAS oncogene family 0.808
FBLN5 fibulin 5 0.806
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.806
LOC102724023 ES1 protein homolog, mitochondrial 0.803
TRAPPC9 trafficking protein particle complex 9 0.802
RMI2 RecQ mediated genome instability 2 0.802
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.801
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.8
SEC23B Sec23 homolog B (S. cerevisiae) 0.792
RAB33B RAB33B, member RAS oncogene family 0.789
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.788
ZFPL1 zinc finger protein-like 1 0.788
ETV6 ets variant 6 0.784
KRT8 keratin 8, type II 0.779
ERP27 endoplasmic reticulum protein 27 0.778
IL1A interleukin 1, alpha 0.777
PDIA4 protein disulfide isomerase family A, member 4 0.772
ADCY10 adenylate cyclase 10 (soluble) 0.767
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.767
NEXN nexilin (F actin binding protein) 0.766
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.766
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.766
RAB10 RAB10, member RAS oncogene family 0.764
MAN1B1 mannosidase, alpha, class 1B, member 1 0.764
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.762
AOX1 aldehyde oxidase 1 0.76
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.759
ASPN asporin 0.758
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 0.757
POGLUT2 protein O-glucosyltransferase 2 0.757
POLL polymerase (DNA directed), lambda 0.756
GOLGA3 golgin A3 0.754
LGALS12 lectin, galactoside-binding, soluble, 12 0.749
PROS1 protein S (alpha) 0.748
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.744
ALYREF Aly/REF export factor 0.735
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.734
TMED4 transmembrane emp24 protein transport domain containing 4 0.73
NCOA2 nuclear receptor coactivator 2 0.726
PEX16 peroxisomal biogenesis factor 16 0.718
DENND4C DENN/MADD domain containing 4C 0.713
OCA2 oculocutaneous albinism II 0.71
TGOLN2 trans-golgi network protein 2 0.707
NCOA1 nuclear receptor coactivator 1 0.707
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 0.704
MOCS1 molybdenum cofactor synthesis 1 0.698
KIF12 kinesin family member 12 0.695
GLB1 galactosidase, beta 1 0.694
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 0.692
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.69
INS insulin 0.688
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 0.685
SCOC short coiled-coil protein 0.684
FBF1 Fas (TNFRSF6) binding factor 1 0.683
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.683
ERGIC2 ERGIC and golgi 2 0.682
ZNF350 zinc finger protein 350 0.681
TRIP11 thyroid hormone receptor interactor 11 0.677
MPPE1 metallophosphoesterase 1 0.676
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.675
EREG epiregulin 0.675
PLA2G12A phospholipase A2, group XIIA 0.674
DAD1 defender against cell death 1 0.668
EEA1 early endosome antigen 1 0.668
ATXN2 ataxin 2 0.666
RPN1 ribophorin I 0.661
ERP29 endoplasmic reticulum protein 29 0.659
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 0.658
MOGAT2 monoacylglycerol O-acyltransferase 2 0.657
EPOR erythropoietin receptor 0.652
TOR1A torsin family 1, member A (torsin A) 0.65
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.65
RNF152 ring finger protein 152 0.649
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.648
LPIN1 lipin 1 0.647
RAB39A RAB39A, member RAS oncogene family 0.646
GLIS3 GLIS family zinc finger 3 0.639
TMEM115 transmembrane protein 115 0.638
REEP3 receptor accessory protein 3 0.634
KIFC2 kinesin family member C2 0.633
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.632
SNTG2 syntrophin, gamma 2 0.629
GORAB golgin, RAB6-interacting 0.625
RMI1 RecQ mediated genome instability 1 0.618
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.618
DERA deoxyribose-phosphate aldolase (putative) 0.617
GOLGA7 golgin A7 0.616
SPAST spastin 0.615
SRP54 signal recognition particle 54kDa 0.612
SEC23IP SEC23 interacting protein 0.612
ARF3 ADP-ribosylation factor 3 0.61
EGF epidermal growth factor 0.604
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.603
SYS1 Sys1 golgi trafficking protein 0.6
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.599
FKBP2 FK506 binding protein 2, 13kDa 0.599
CHD7 chromodomain helicase DNA binding protein 7 0.598
PDZD2 PDZ domain containing 2 0.598
ZW10 zw10 kinetochore protein 0.597
TSPO translocator protein (18kDa) 0.595
SOGA1 suppressor of glucose, autophagy associated 1 0.593
ERGIC3 ERGIC and golgi 3 0.59
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 0.59
COPG2 coatomer protein complex, subunit gamma 2 0.587
NEURL1 neuralized E3 ubiquitin protein ligase 1 0.585
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 0.584
NCAPG non-SMC condensin I complex, subunit G 0.584
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.583
DHFR dihydrofolate reductase 0.582
RGN regucalcin 0.577
WRN Werner syndrome, RecQ helicase-like 0.576
NANOS1 nanos homolog 1 (Drosophila) 0.575
CLUH clustered mitochondria (cluA/CLU1) homolog 0.574
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 0.573
IL6 interleukin 6 0.573
CD8A CD8a molecule 0.571
UBXN4 UBX domain protein 4 0.571
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.57
NSMCE3 NSE3 homolog, SMC5-SMC6 complex component 0.568
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 0.564
PECR peroxisomal trans-2-enoyl-CoA reductase 0.563
DNAH8 dynein, axonemal, heavy chain 8 0.558
PDCD6 programmed cell death 6 0.558
FNTA farnesyltransferase, CAAX box, alpha 0.557
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 0.555
COL1A2 collagen, type I, alpha 2 0.554
AP5M1 adaptor-related protein complex 5, mu 1 subunit 0.553
MON2 MON2 homolog (S. cerevisiae) 0.553
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.552
ENGASE endo-beta-N-acetylglucosaminidase 0.55
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.546
GRIPAP1 GRIP1 associated protein 1 0.543
IL1B interleukin 1, beta 0.543
FLAD1 flavin adenine dinucleotide synthetase 1 0.542
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 0.541
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.54
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.539
GRAP GRB2-related adaptor protein 0.539
IFNG interferon, gamma 0.539
TBC1D20 TBC1 domain family, member 20 0.538
ATF6 activating transcription factor 6 0.536
IL2 interleukin 2 0.535
NTS neurotensin 0.532
RAB43 RAB43, member RAS oncogene family 0.532
RAB30 RAB30, member RAS oncogene family 0.531
PCNT pericentrin 0.53
TMEM33 transmembrane protein 33 0.529
HSPA4 heat shock 70kDa protein 4 0.529
DDHD1 DDHD domain containing 1 0.528
ARF4 ADP-ribosylation factor 4 0.527
ERBB2 erb-b2 receptor tyrosine kinase 2 0.527
CNRIP1 cannabinoid receptor interacting protein 1 0.525
GOLGA1 golgin A1 0.523
ABR active BCR-related 0.521
FATE1 fetal and adult testis expressed 1 0.519
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.518
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.517
VANGL2 VANGL planar cell polarity protein 2 0.517
PGK1 phosphoglycerate kinase 1 0.513
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.513
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.512
EXOC6 exocyst complex component 6 0.512
WAS Wiskott-Aldrich syndrome 0.512
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.512
EXOC3 exocyst complex component 3 0.511
SHLD1 shieldin complex subunit 1 0.509
EXOC4 exocyst complex component 4 0.509
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.508
GAS1 growth arrest-specific 1 0.506
RAD52 RAD52 homolog (S. cerevisiae) 0.501