DNA-templated transcription initiation Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. (Gene Ontology, GO_0006352)
External Link http://amigo.geneontology.org/amigo/term/GO_0006352
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Genes

60 genes participating in the DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
CAVIN1 caveolae associated protein 1
CCNH cyclin H
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CRCP CGRP receptor component
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
ELOA elongin A
ELOB elongin B
ELOC elongin C
ERCC3 excision repair cross-complementation group 3
GTF2A2 general transcription factor IIA, 2, 12kDa
GTF2B general transcription factor IIB
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MED17 mediator complex subunit 17
MED23 mediator complex subunit 23
MED26 mediator complex subunit 26
MED27 mediator complex subunit 27
MED7 mediator complex subunit 7
NAT14 N-acetyltransferase 14 (GCN5-related, putative)
NCOA6 nuclear receptor coactivator 6
PAAF1 proteasomal ATPase-associated factor 1
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RRN3P2 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
RSF1 remodeling and spacing factor 1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TBP TATA box binding protein
TBPL1 TBP-like 1
TBPL2 TATA box binding protein like 2
TFAM transcription factor A, mitochondrial
TFB1M transcription factor B1, mitochondrial
TFB2M transcription factor B2, mitochondrial
UBTF upstream binding transcription factor, RNA polymerase I
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2