DNMT1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description DNA (cytosine-5-)-methyltransferase 1|DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] (NCBI Entrez Gene Database, 1786)
External Link https://ncbi.nlm.nih.gov/gene/1786
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Genes

499 genes differentially expressed following the DNMT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A 0.0124197
PCP4 Purkinje cell protein 4 0.0103251
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00982237
TM4SF1 transmembrane 4 L six family member 1 0.00886834
CEMIP cell migration inducing protein, hyaluronan binding 0.00882525
ODC1 ornithine decarboxylase 1 0.00880501
CD9 CD9 molecule 0.00869576
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00814398
CXADR coxsackie virus and adenovirus receptor 0.00794525
EMX2 empty spiracles homeobox 2 0.00784234
AEBP1 AE binding protein 1 0.00782312
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00778795
MSMB microseminoprotein, beta- 0.00767809
TMSB15A thymosin beta 15a 0.00761222
MSLN mesothelin 0.00758617
MT1G metallothionein 1G 0.00748128
GATA6 GATA binding protein 6 0.00737481
GPNMB glycoprotein (transmembrane) nmb 0.00726146
DPYSL3 dihydropyrimidinase-like 3 0.00716457
MUC4 mucin 4, cell surface associated 0.00713218
H1-2 H1.2 linker histone, cluster member 0.00710655
MT1F metallothionein 1F 0.00708255
IGFBP5 insulin-like growth factor binding protein 5 0.00696984
MT1E metallothionein 1E 0.00690254
KLK11 kallikrein-related peptidase 11 0.00689765
KLK10 kallikrein-related peptidase 10 0.00688529
WT1 Wilms tumor 1 0.00673743
BGN biglycan 0.00673077
THBS2 thrombospondin 2 0.0066773
CRIP1 cysteine-rich protein 1 (intestinal) 0.00664657
EFNB2 ephrin-B2 0.0065933
TUBB2A tubulin, beta 2A class IIa 0.00657651
ECM1 extracellular matrix protein 1 0.00652983
SFRP4 secreted frizzled-related protein 4 0.00652454
TACC2 transforming, acidic coiled-coil containing protein 2 0.0064905
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00641893
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00618854
L1CAM L1 cell adhesion molecule 0.00615238
MDK midkine (neurite growth-promoting factor 2) 0.00613644
DUOX2 dual oxidase 2 0.00605042
TMEM14B transmembrane protein 14B 0.00595446
MT1H metallothionein 1H 0.00593582
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00586453
GPX2 glutathione peroxidase 2 0.00582875
FAM171A1 family with sequence similarity 171, member A1 0.00582165
RIPK4 receptor-interacting serine-threonine kinase 4 0.00581214
TSPAN8 tetraspanin 8 0.00578492
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00573231
INAVA innate immunity activator 0.00570752
ISG20 interferon stimulated exonuclease gene 20kDa 0.00568231
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00566415
MAMLD1 mastermind-like domain containing 1 0.00559444
ZNF185 zinc finger protein 185 (LIM domain) 0.00556939
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0055639
AQP3 aquaporin 3 (Gill blood group) 0.0055625
DENND2B DENN domain containing 2B 0.0055575
IRF4 interferon regulatory factor 4 0.00555227
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00555151
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00553456
ENO2 enolase 2 (gamma, neuronal) 0.00551339
OCRL oculocerebrorenal syndrome of Lowe 0.00543538
C14ORF132 chromosome 14 open reading frame 132 0.00543389
COMP cartilage oligomeric matrix protein 0.00542413
GCH1 GTP cyclohydrolase 1 0.0054238
DCT dopachrome tautomerase 0.00542222
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00540831
KLK6 kallikrein-related peptidase 6 0.0054016
CLTB clathrin, light chain B 0.00535927
PMEL premelanosome protein 0.00535529
PRUNE2 prune homolog 2 (Drosophila) 0.00534804
C1S complement component 1, s subcomponent 0.00534692
PTBP2 polypyrimidine tract binding protein 2 0.00532458
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00532139
ACP3 acid phosphatase 3 0.00531513
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00529469
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00524607
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00522904
HSPB1 heat shock 27kDa protein 1 0.00520669
EIF4A3 eukaryotic translation initiation factor 4A3 0.0052054
CD38 CD38 molecule 0.00520466
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.0052023
SORBS3 sorbin and SH3 domain containing 3 0.00519986
CXCL10 chemokine (C-X-C motif) ligand 10 0.00515316
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00511719
ADCY1 adenylate cyclase 1 (brain) 0.00509984
JAG1 jagged 1 0.00505872
COL9A2 collagen, type IX, alpha 2 0.00502924
LAMP5 lysosomal-associated membrane protein family, member 5 0.00502554
FMOD fibromodulin 0.005018
NPY neuropeptide Y 0.00496571
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00496115
ADIRF adipogenesis regulatory factor 0.00496074
BAMBI BMP and activin membrane-bound inhibitor 0.00494335
CSRP1 cysteine and glycine-rich protein 1 0.00493024
MEIS2 Meis homeobox 2 0.00491707
KIF1B kinesin family member 1B 0.00487843
WNT5B wingless-type MMTV integration site family, member 5B 0.00487132
FRMD4B FERM domain containing 4B 0.00486396
IFI27 interferon, alpha-inducible protein 27 0.004839
LAPTM4B lysosomal protein transmembrane 4 beta 0.00481433
BTG3 BTG family, member 3 0.00480851
PER2 period circadian clock 2 0.00477189
POSTN periostin, osteoblast specific factor 0.00476959
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00476956
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00474498
ATP10B ATPase, class V, type 10B 0.0047429
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00474277
MT2A metallothionein 2A 0.00474118
C9ORF3 chromosome 9 open reading frame 3 0.00473775
TLK2 tousled-like kinase 2 0.00472822
PRSS21 protease, serine, 21 (testisin) 0.00471717
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00470959
MFAP2 microfibrillar-associated protein 2 0.00468739
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00468375
AHNAK2 AHNAK nucleoprotein 2 0.00467934
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00467341
MT1HL1 metallothionein 1H-like 1 0.00463772
LTBP2 latent transforming growth factor beta binding protein 2 0.00462731
C3 complement component 3 0.00461824
SVIL supervillin 0.00460798
C1R complement component 1, r subcomponent 0.00460089
PNOC prepronociceptin 0.00458983
FLNA filamin A, alpha 0.00458611
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00458439
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00457104
IL1R1 interleukin 1 receptor, type I 0.00454834
PRDX1 peroxiredoxin 1 0.00454273
DOK5 docking protein 5 0.00454018
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00453532
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00452278
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00450015
CTSK cathepsin K 0.00449753
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00448819
GALC galactosylceramidase 0.00447341
FCGBP Fc fragment of IgG binding protein 0.00446817
CPB1 carboxypeptidase B1 (tissue) 0.00445109
MYH10 myosin, heavy chain 10, non-muscle 0.00444389
LCN2 lipocalin 2 0.00443118
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00442976
SPARCL1 SPARC-like 1 (hevin) 0.00442884
CLCA4 chloride channel accessory 4 0.00441401
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00441011
ACAT2 acetyl-CoA acetyltransferase 2 0.00440993
OPTN optineurin 0.00439881
FBXL7 F-box and leucine-rich repeat protein 7 0.0043973
BIK BCL2-interacting killer (apoptosis-inducing) 0.0043925
PRKCI protein kinase C, iota 0.00438475
CES1 carboxylesterase 1 0.00437678
LGALS4 lectin, galactoside-binding, soluble, 4 0.00434022
CLIC5 chloride intracellular channel 5 0.00430816
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.00429607
NINL ninein-like 0.00428779
UNC13B unc-13 homolog B (C. elegans) 0.00428467
DCTN2 dynactin 2 (p50) 0.00428021
S100A10 S100 calcium binding protein A10 0.00425543
COL6A3 collagen, type VI, alpha 3 0.0042497
TP53I3 tumor protein p53 inducible protein 3 0.00424602
SYNPO synaptopodin 0.00422132
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00421495
CENPF centromere protein F, 350/400kDa 0.0042012
TFF1 trefoil factor 1 0.00418966
NYNRIN NYN domain and retroviral integrase containing 0.00417523
CLCA1 chloride channel accessory 1 0.00417063
AKAP12 A kinase (PRKA) anchor protein 12 0.00415546
OSR2 odd-skipped related transciption factor 2 0.00415156
MEIS1 Meis homeobox 1 0.00414782
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00414752
MAL mal, T-cell differentiation protein 0.00413656
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00412837
PITX3 paired-like homeodomain 3 0.00411786
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00411367
DNMBP dynamin binding protein 0.00410975
PLA2G10 phospholipase A2, group X 0.0040928
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00408754
TENM4 teneurin transmembrane protein 4 0.00405927
AVPI1 arginine vasopressin-induced 1 0.00404995
FXYD3 FXYD domain containing ion transport regulator 3 0.00404326
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00404014
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00401581
SYT1 synaptotagmin I 0.0040092
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.00400844
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00400444
COPZ2 coatomer protein complex, subunit zeta 2 0.00400135
KLK7 kallikrein-related peptidase 7 0.00400084
AK4 adenylate kinase 4 0.00399627
ARID4A AT rich interactive domain 4A (RBP1-like) 0.003994
MAOB monoamine oxidase B 0.00399394
EGFL6 EGF-like-domain, multiple 6 0.00398049
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.0039558
KLK1 kallikrein 1 0.00395219
MYRF myelin regulatory factor 0.00394992
STC1 stanniocalcin 1 0.0039474
RGS2 regulator of G-protein signaling 2 0.00394609
OCA2 oculocutaneous albinism II 0.00394184
ATXN1 ataxin 1 0.00393303
BMP7 bone morphogenetic protein 7 0.00393185
KLK8 kallikrein-related peptidase 8 0.00392813
SMAD2 SMAD family member 2 0.0039242
DENND2D DENN/MADD domain containing 2D 0.00391963
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0039114
POF1B premature ovarian failure, 1B 0.00390485
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00390407
CDC25A cell division cycle 25A 0.00390097
BCAS1 breast carcinoma amplified sequence 1 0.00388716
KLK5 kallikrein-related peptidase 5 0.0038845
PFN2 profilin 2 0.00388079
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00386618
FN1 fibronectin 1 0.00385412
POU2AF1 POU class 2 associating factor 1 0.00385098
PCNA proliferating cell nuclear antigen 0.00384134
OSBPL10 oxysterol binding protein-like 10 0.00383883
NMU neuromedin U 0.00383716
RASAL1 RAS protein activator like 1 (GAP1 like) 0.00383127
TASP1 taspase, threonine aspartase, 1 0.00382824
EPYC epiphycan 0.00381731
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00381483
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0038136
PLBD1 phospholipase B domain containing 1 0.00381068
TARP TCR gamma alternate reading frame protein 0.00380585
RNF43 ring finger protein 43 0.00379106
APOC1 apolipoprotein C-I 0.00378176
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00377351
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.00376907
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.00375798
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00374835
ATP9A ATPase, class II, type 9A 0.00374782
CCN2 cellular communication network factor 2 0.00374303
CXCL2 chemokine (C-X-C motif) ligand 2 0.00374259
MUC13 mucin 13, cell surface associated 0.00373171
ICOS inducible T-cell co-stimulator 0.0037238
PLCD1 phospholipase C, delta 1 0.00371356
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.00371322
ACKR3 atypical chemokine receptor 3 0.00371259
PRAME preferentially expressed antigen in melanoma 0.0037073
BAX BCL2-associated X protein 0.00370378
KIF5C kinesin family member 5C 0.00368842
ARMCX1 armadillo repeat containing, X-linked 1 0.00368548
C21ORF91 chromosome 21 open reading frame 91 0.00366267
ATF5 activating transcription factor 5 0.00365874
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.00365836
CXCL8 chemokine (C-X-C motif) ligand 8 0.00365559
LMCD1 LIM and cysteine-rich domains 1 0.00365523
SYT11 synaptotagmin XI 0.00364757
SULF1 sulfatase 1 0.00364574
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00364394
CRABP2 cellular retinoic acid binding protein 2 0.00362952
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00362899
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00362762
CCNF cyclin F 0.00362653
DEFB1 defensin, beta 1 0.00360604

decreased expression

Symbol Name Standardized Value
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.0186316
SCGB2A2 secretoglobin, family 2A, member 2 -0.0156679
LTF lactotransferrin -0.0112126
PRDX2 peroxiredoxin 2 -0.00971874
SCGB1D2 secretoglobin, family 1D, member 2 -0.00965432
CPA3 carboxypeptidase A3 (mast cell) -0.00845438
CCDC92 coiled-coil domain containing 92 -0.00832035
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00829583
KRT23 keratin 23, type I -0.00827864
ASPH aspartate beta-hydroxylase -0.00820237
ZBTB18 zinc finger and BTB domain containing 18 -0.00814559
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00760827
FABP7 fatty acid binding protein 7, brain -0.00748722
METRN meteorin, glial cell differentiation regulator -0.00734573
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00729512
PLPP2 phospholipid phosphatase 2 -0.00724024
F13A1 coagulation factor XIII, A1 polypeptide -0.00710976
PTN pleiotrophin -0.00700601
EIF3G eukaryotic translation initiation factor 3, subunit G -0.0069202
NLGN4X neuroligin 4, X-linked -0.00672261
S100A8 S100 calcium binding protein A8 -0.00664929
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.0064856
STC2 stanniocalcin 2 -0.00647408
S100A9 S100 calcium binding protein A9 -0.00647359
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00643894
MSX1 msh homeobox 1 -0.0064164
PIP prolactin-induced protein -0.00640792
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00639672
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00628359
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00627647
FNDC3B fibronectin type III domain containing 3B -0.00623448
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00619677
C4BPA complement component 4 binding protein, alpha -0.00617831
CADPS2 Ca++-dependent secretion activator 2 -0.00615106
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00608951
TPBG trophoblast glycoprotein -0.00608044
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00596274
PDZK1 PDZ domain containing 1 -0.00593037
MREG melanoregulin -0.00591626
TTN titin -0.00591197
TNNC1 troponin C type 1 (slow) -0.00589887
CSNK1G2 casein kinase 1, gamma 2 -0.00588504
G0S2 G0/G1 switch 2 -0.00584882
GLUL glutamate-ammonia ligase -0.00584242
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00584159
MYBPC1 myosin binding protein C, slow type -0.00578991
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00575566
GJA1 gap junction protein, alpha 1, 43kDa -0.00575239
CFD complement factor D (adipsin) -0.00569425
TOR1A torsin family 1, member A (torsin A) -0.00560703
OLFM1 olfactomedin 1 -0.00553962
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00542929
KLHL41 kelch-like family member 41 -0.0053289
SUB1 SUB1 homolog (S. cerevisiae) -0.0053251
GPX4 glutathione peroxidase 4 -0.00531926
LIMCH1 LIM and calponin homology domains 1 -0.00531011
MPO myeloperoxidase -0.00529877
MFAP3L microfibrillar-associated protein 3-like -0.00529725
RTN2 reticulon 2 -0.00529012
TNS3 tensin 3 -0.00526737
ACTA1 actin, alpha 1, skeletal muscle -0.00525842
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00520758
TYROBP TYRO protein tyrosine kinase binding protein -0.00519328
SDC2 syndecan 2 -0.00519165
GSTM3 glutathione S-transferase mu 3 (brain) -0.00514583
SCGB2A1 secretoglobin, family 2A, member 1 -0.00508666
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00507077
TLR2 toll-like receptor 2 -0.0050632
CNN2 calponin 2 -0.00499252
CIAPIN1 cytokine induced apoptosis inhibitor 1 -0.00499229
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00497992
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00496937
TNNC2 troponin C type 2 (fast) -0.00495606
RAD23A RAD23 homolog A (S. cerevisiae) -0.00492009
RNASEH2A ribonuclease H2, subunit A -0.00492002
HNMT histamine N-methyltransferase -0.00487143
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.00485687
MB myoglobin -0.0048524
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00481483
RCAN1 regulator of calcineurin 1 -0.00480011
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00479203
GPC4 glypican 4 -0.00478747
CD320 CD320 molecule -0.00478273
TPSAB1 tryptase alpha/beta 1 -0.00473865
ABHD17A abhydrolase domain containing 17A -0.00473248
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00470518
TNNI1 troponin I type 1 (skeletal, slow) -0.0046872
CANX calnexin -0.0046821
OAZ1 ornithine decarboxylase antizyme 1 -0.00466946
COTL1 coactosin-like F-actin binding protein 1 -0.00465445
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00464435
BTBD3 BTB (POZ) domain containing 3 -0.00464334
WNT5A wingless-type MMTV integration site family, member 5A -0.00463186
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00461655
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00457935
PQBP1 polyglutamine binding protein 1 -0.00457091
NELL1 NEL-like 1 (chicken) -0.00456
ADAM12 ADAM metallopeptidase domain 12 -0.00455613
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00455466
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00454844
STK10 serine/threonine kinase 10 -0.00454658
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00453774
NPY1R neuropeptide Y receptor Y1 -0.00452235
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.0045208
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00451755
VAV3 vav 3 guanine nucleotide exchange factor -0.00449532
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00449079
MYBPC2 myosin binding protein C, fast type -0.00448563
CLEC7A C-type lectin domain family 7, member A -0.00445662
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00444941
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00442903
FADS1 fatty acid desaturase 1 -0.00442435
GSE1 Gse1 coiled-coil protein -0.00440975
DEPTOR DEP domain containing MTOR-interacting protein -0.00440781
ANXA1 annexin A1 -0.0044053
CD99 CD99 molecule -0.00440368
CD36 CD36 molecule (thrombospondin receptor) -0.0044012
CKM creatine kinase, muscle -0.00437675
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00437332
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00436429
CSF3R colony stimulating factor 3 receptor (granulocyte) -0.00434294
ITGA6 integrin, alpha 6 -0.00431202
TNNI2 troponin I type 2 (skeletal, fast) -0.004305
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00429937
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.00429736
COPS7A COP9 signalosome subunit 7A -0.00425236
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -0.0042008
LMAN1 lectin, mannose-binding, 1 -0.00418831
ASRGL1 asparaginase like 1 -0.00418002
IL7R interleukin 7 receptor -0.0041789
RIDA reactive intermediate imine deaminase A homolog -0.00417724
CYB5A cytochrome b5 type A (microsomal) -0.00415464
ZNF91 zinc finger protein 91 -0.00414709
TSPAN13 tetraspanin 13 -0.00412269
TLE5 TLE family member 5, transcriptional modulator -0.00411592
MAPK9 mitogen-activated protein kinase 9 -0.00410851
ITM2A integral membrane protein 2A -0.00409792
AKAP7 A kinase (PRKA) anchor protein 7 -0.00409505
RAB14 RAB14, member RAS oncogene family -0.00409059
TMEM45A transmembrane protein 45A -0.00408366
LYST lysosomal trafficking regulator -0.00408188
MCTP1 multiple C2 domains, transmembrane 1 -0.00406133
CENPU centromere protein U -0.0040606
LONP1 lon peptidase 1, mitochondrial -0.00404952
MET MET proto-oncogene, receptor tyrosine kinase -0.00404785
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00402572
ARMCX3 armadillo repeat containing, X-linked 3 -0.00402438
GDE1 glycerophosphodiester phosphodiesterase 1 -0.00400694
PF4 platelet factor 4 -0.0040066
EHD3 EH-domain containing 3 -0.00400344
TMEM259 transmembrane protein 259 -0.00400051
ARHGAP45 Rho GTPase activating protein 45 -0.00399569
DLX5 distal-less homeobox 5 -0.0039937
CST6 cystatin E/M -0.00399068
NRN1 neuritin 1 -0.00398915
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.0039858
NFE2 nuclear factor, erythroid 2 -0.00396606
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -0.00394562
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00393729
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.00393145
KAZN kazrin, periplakin interacting protein -0.00391182
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -0.00390983
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00390659
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00390136
S100A7 S100 calcium binding protein A7 -0.00390101
OPN3 opsin 3 -0.00390099
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -0.00388873
TUSC3 tumor suppressor candidate 3 -0.00388532
FBN2 fibrillin 2 -0.00387779
GRB14 growth factor receptor-bound protein 14 -0.00387263
PAQR6 progestin and adipoQ receptor family member VI -0.00386081
ELOVL5 ELOVL fatty acid elongase 5 -0.00385457
COL21A1 collagen, type XXI, alpha 1 -0.00385125
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00382646
ECSIT ECSIT signalling integrator -0.00382557
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00381091
SIRPA signal-regulatory protein alpha -0.00380949
RXRA retinoid X receptor, alpha -0.00378656
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00377651
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00377597
GPM6B glycoprotein M6B -0.00377484
CD164 CD164 molecule, sialomucin -0.0037685
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.00376319
SLITRK5 SLIT and NTRK-like family, member 5 -0.0037606
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.0037518
STXBP2 syntaxin binding protein 2 -0.00374802
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.00374591
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00374446
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -0.00373917
NRXN1 neurexin 1 -0.00373674
CTBP1 C-terminal binding protein 1 -0.00373284
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00373246
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -0.00372399
PTCH1 patched 1 -0.00370643
NBN nibrin -0.00370545
RPS28 ribosomal protein S28 -0.00370074
BTG1 B-cell translocation gene 1, anti-proliferative -0.00369822
TMED5 transmembrane emp24 protein transport domain containing 5 -0.00369438
NMRK1 nicotinamide riboside kinase 1 -0.00368377
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00368351
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -0.00368037
PPP1R17 protein phosphatase 1, regulatory subunit 17 -0.00366407
PDE4DIP phosphodiesterase 4D interacting protein -0.00366406
NELL2 NEL-like 2 (chicken) -0.00366245
PWWP3A PWWP domain containing 3A, DNA repair factor -0.00366146
METTL7A methyltransferase like 7A -0.00365972
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00365614
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00363773
SELL selectin L -0.00363394
RBM34 RNA binding motif protein 34 -0.00361212
MYDGF myeloid-derived growth factor -0.0036031
NOL12 nucleolar protein 12 -0.00358918
C19ORF53 chromosome 19 open reading frame 53 -0.00358037
NUP85 nucleoporin 85kDa -0.00357587
CDC37 cell division cycle 37 -0.00357192
PADI3 peptidyl arginine deiminase, type III -0.00356735
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -0.00356162
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 -0.00355987
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.00355725
EIF5 eukaryotic translation initiation factor 5 -0.00355643
EREG epiregulin -0.00355169
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00355056
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.0035494
CALCB calcitonin-related polypeptide beta -0.00354674
RPL36 ribosomal protein L36 -0.00353361
CYB561 cytochrome b561 -0.00353134
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.00353013
FEN1 flap structure-specific endonuclease 1 -0.0035276
TPM3 tropomyosin 3 -0.00351875
SET SET nuclear proto-oncogene -0.00351862
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00351268
MID1IP1 MID1 interacting protein 1 -0.00350658
MRPL11 mitochondrial ribosomal protein L11 -0.0035055
RC3H2 ring finger and CCCH-type domains 2 -0.00349977
DHFR dihydrofolate reductase -0.00349467
MRPL4 mitochondrial ribosomal protein L4 -0.00349095
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -0.00347439
FRS2 fibroblast growth factor receptor substrate 2 -0.00347371
RNF130 ring finger protein 130 -0.00347194
MTCL1 microtubule crosslinking factor 1 -0.00347006
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.0034647
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00346379
DENND5A DENN/MADD domain containing 5A -0.00346041
ZNF274 zinc finger protein 274 -0.00345673
NOTCH1 notch 1 -0.00345557
XYLT1 xylosyltransferase I -0.00345312
FHL1 four and a half LIM domains 1 -0.0034482
TLE4 transducin-like enhancer of split 4 -0.00344066
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00343889