DORZOLAMIDE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. (Chemical Entities of Biological Interest Ontology, CHEBI_4702)
External Link https://dgidb.org/results?searchType=drug&searchTerms=DORZOLAMIDE
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Genes

4 interacting proteins for the DORZOLAMIDE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
CA14 carbonic anhydrase XIV 1.65412
CA7 carbonic anhydrase VII 0.778412
CA2 carbonic anhydrase II 0.401
CA1 carbonic anhydrase I 0.367583