DOXACURIUM CHLORIDE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description The dichloride salt of doxacurium. It is a mixture of the (1R,2S,1'S,2'R), (1R,2S,1'R,2'S) and (1S,2R,1'S,2'R) stereoisomers (a meso isomer and two enantiomers, respectively) of 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxypropane-3,1-diyl)]bis[6,7,8-trimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolinium] dichloride, all of which are in a trans configuration at the 1 and 2 positions of the tetrahydroisoquinolinium rings. A competitive neuromuscular blocker, it is used to provide muscle relaxation in general anaesthesia and to facilitate mechanical ventilation in patients in intensive care. (Chemical Entities of Biological Interest Ontology, CHEBI_4707)
External Link https://dgidb.org/results?searchType=drug&searchTerms=DOXACURIUM CHLORIDE
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Genes

2 interacting proteins for the DOXACURIUM CHLORIDE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 2.03585
CHRM2 cholinergic receptor, muscarinic 2 0.365048