DPP6 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description dipeptidyl-peptidase 6|This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 1804)
External Link http://www.ncbi.nlm.nih.gov/gene/1804
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Genes

2 interacting proteins for DPP6 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
PHB prohibitin