| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | DR1-associated protein 1 (negative cofactor 2 alpha)|Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10589) |
| External Link | https://ncbi.nlm.nih.gov/gene/10589 |
| Similar Terms | |
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498 genes differentially expressed following the DRAP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0100121 |
| S100P | S100 calcium binding protein P | 0.00988955 |
| LTF | lactotransferrin | 0.00911157 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00855261 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00828688 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00823246 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00821623 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00810457 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00796312 |
| LCN2 | lipocalin 2 | 0.00791972 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00791755 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00790405 |
| S100A9 | S100 calcium binding protein A9 | 0.00787621 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00760025 |
| KYNU | kynureninase | 0.00753688 |
| FBLN1 | fibulin 1 | 0.00745713 |
| PLTP | phospholipid transfer protein | 0.00734187 |
| MMP12 | matrix metallopeptidase 12 | 0.00734165 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00731647 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00729975 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00724778 |
| HMG20B | high mobility group 20B | 0.00722067 |
| SATB2 | SATB homeobox 2 | 0.00720063 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00718312 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00716834 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.00710321 |
| VCAN | versican | 0.00684725 |
| ITGB4 | integrin, beta 4 | 0.00683211 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00682907 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00673263 |
| BCL2A1 | BCL2-related protein A1 | 0.0067204 |
| OLFM4 | olfactomedin 4 | 0.0066865 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.0066772 |
| CSTA | cystatin A (stefin A) | 0.00659043 |
| MYO5C | myosin VC | 0.00644132 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00639798 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00637489 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00627368 |
| AEBP1 | AE binding protein 1 | 0.00625585 |
| GPX2 | glutathione peroxidase 2 | 0.00615242 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00613928 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00612627 |
| CD14 | CD14 molecule | 0.0060802 |
| C3 | complement component 3 | 0.00601999 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00598337 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 0.00598234 |
| METRN | meteorin, glial cell differentiation regulator | 0.00595356 |
| C1S | complement component 1, s subcomponent | 0.00592069 |
| G0S2 | G0/G1 switch 2 | 0.00590273 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00589876 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00588781 |
| CTSZ | cathepsin Z | 0.00588308 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | 0.00584347 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.00581761 |
| GAS1 | growth arrest-specific 1 | 0.00580843 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00580706 |
| CD200 | CD200 molecule | 0.00577342 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0057309 |
| MARCKSL1 | MARCKS-like 1 | 0.00572702 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00571597 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00571261 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.00569181 |
| CD86 | CD86 molecule | 0.00568796 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00567806 |
| STXBP2 | syntaxin binding protein 2 | 0.00567637 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.0056117 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00558317 |
| TOX3 | TOX high mobility group box family member 3 | 0.00556127 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.0055511 |
| NANS | N-acetylneuraminic acid synthase | 0.00554486 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00552955 |
| KLF10 | Kruppel-like factor 10 | 0.00552624 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0054965 |
| TFF1 | trefoil factor 1 | 0.00546395 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00543619 |
| KRT19 | keratin 19, type I | 0.00543246 |
| ZNF423 | zinc finger protein 423 | 0.00542511 |
| FLOT2 | flotillin 2 | 0.00540959 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0053916 |
| S100A7 | S100 calcium binding protein A7 | 0.00538748 |
| IRF2 | interferon regulatory factor 2 | 0.00537565 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00536572 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00531473 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00530943 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.00528976 |
| LOXL1 | lysyl oxidase-like 1 | 0.00527647 |
| TOR3A | torsin family 3, member A | 0.00527426 |
| BAX | BCL2-associated X protein | 0.0052465 |
| NINJ1 | ninjurin 1 | 0.00521002 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00518988 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00518268 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.0051812 |
| MAGEA3 | melanoma antigen family A3 | 0.00517844 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.00516385 |
| C1R | complement component 1, r subcomponent | 0.00516062 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00515919 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00514403 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.00512558 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00512331 |
| NARF | nuclear prelamin A recognition factor | 0.00511612 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00510224 |
| ADAP1 | ArfGAP with dual PH domains 1 | 0.00510125 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00509527 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00508099 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00507946 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00506313 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00503989 |
| PLN | phospholamban | 0.00501807 |
| CDCA4 | cell division cycle associated 4 | 0.00501799 |
| CD93 | CD93 molecule | 0.00500158 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00498579 |
| PRR5 | proline rich 5 (renal) | 0.00496432 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | 0.00496165 |
| EPHB4 | EPH receptor B4 | 0.00495972 |
| TOB1 | transducer of ERBB2, 1 | 0.00493741 |
| ORC5 | origin recognition complex, subunit 5 | 0.00492884 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00492101 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.0049151 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00488892 |
| VWF | von Willebrand factor | 0.0048547 |
| DCN | decorin | 0.00485139 |
| DPEP1 | dipeptidase 1 (renal) | 0.00483815 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00483431 |
| STOM | stomatin | 0.00483121 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00482939 |
| MSMB | microseminoprotein, beta- | 0.00482439 |
| LYZ | lysozyme | 0.00480987 |
| HEPH | hephaestin | 0.00478933 |
| FA2H | fatty acid 2-hydroxylase | 0.00478816 |
| PRKCA | protein kinase C, alpha | 0.00476709 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00475409 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00475194 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00474521 |
| TMEM176B | transmembrane protein 176B | 0.00473903 |
| CFD | complement factor D (adipsin) | 0.00472673 |
| DMD | dystrophin | 0.00471818 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00471736 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | 0.00471346 |
| FOXC1 | forkhead box C1 | 0.00471016 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00470585 |
| KRT20 | keratin 20, type I | 0.0047051 |
| PROM1 | prominin 1 | 0.00470058 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00468914 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00466972 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00466483 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00466068 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 0.00465964 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.00465731 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.004657 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00465526 |
| TMC5 | transmembrane channel-like 5 | 0.00464345 |
| SPP1 | secreted phosphoprotein 1 | 0.0046319 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00462895 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0046227 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00461039 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00460802 |
| FZD5 | frizzled class receptor 5 | 0.00460359 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00459626 |
| TLK2 | tousled-like kinase 2 | 0.00458517 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.00458297 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00458245 |
| INSR | insulin receptor | 0.00458093 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00457372 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00456733 |
| TNC | tenascin C | 0.00456584 |
| MUC4 | mucin 4, cell surface associated | 0.00456265 |
| PLXNC1 | plexin C1 | 0.00456222 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00453941 |
| MLPH | melanophilin | 0.00453779 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 0.00452998 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0045174 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.00450668 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00450029 |
| BGN | biglycan | 0.00450006 |
| PRDX4 | peroxiredoxin 4 | 0.00449541 |
| OPN3 | opsin 3 | 0.00448892 |
| SEC24A | SEC24 family member A | 0.00448326 |
| LEFTY1 | left-right determination factor 1 | 0.00447658 |
| BRD4 | bromodomain containing 4 | 0.00446275 |
| CTSK | cathepsin K | 0.00446201 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00445641 |
| KLK11 | kallikrein-related peptidase 11 | 0.00444456 |
| COCH | cochlin | 0.00444236 |
| LXN | latexin | 0.00443466 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00442759 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00441082 |
| KRT15 | keratin 15, type I | 0.00440706 |
| HMGB3 | high mobility group box 3 | 0.00439873 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | 0.00439477 |
| IL1RN | interleukin 1 receptor antagonist | 0.00438095 |
| POMZP3 | POM121 and ZP3 fusion | 0.00437953 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00436363 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00436219 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00435755 |
| CTSB | cathepsin B | 0.00435546 |
| EFHD2 | EF-hand domain family, member D2 | 0.00433829 |
| RNF167 | ring finger protein 167 | 0.00433794 |
| CD27 | CD27 molecule | 0.00432997 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00432979 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00432828 |
| AOC3 | amine oxidase, copper containing 3 | 0.00432582 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00432205 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00431505 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00430735 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00430612 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00429963 |
| KLF2 | Kruppel-like factor 2 | 0.00429852 |
| LAMB1 | laminin, beta 1 | 0.0042824 |
| SRGN | serglycin | 0.00427705 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00424868 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 0.00424804 |
| IL33 | interleukin 33 | 0.00423474 |
| NOSIP | nitric oxide synthase interacting protein | 0.00423463 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00422706 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0042219 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00421363 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.00421126 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00420845 |
| SMAD2 | SMAD family member 2 | 0.00420094 |
| SPDEF | SAM pointed domain containing ETS transcription factor | 0.00418937 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00417808 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.0041765 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00416646 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00416474 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00415874 |
| LIPG | lipase, endothelial | 0.0041479 |
| EMILIN1 | elastin microfibril interfacer 1 | 0.0041435 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00414143 |
| IQCG | IQ motif containing G | 0.00413916 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00412664 |
| TGM2 | transglutaminase 2 | 0.00412557 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00411497 |
| PLPP3 | phospholipid phosphatase 3 | 0.00410682 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00410089 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | 0.00409488 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00409239 |
| KAZN | kazrin, periplakin interacting protein | 0.00408841 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00407699 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00406926 |
| RFK | riboflavin kinase | 0.00406818 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00406356 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00404403 |
| LY86 | lymphocyte antigen 86 | 0.00403511 |
| ACKR3 | atypical chemokine receptor 3 | 0.00403164 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.0040149 |
| E2F2 | E2F transcription factor 2 | 0.00400976 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00399481 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00398617 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.0144259 |
| CADM1 | cell adhesion molecule 1 | -0.0126535 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0123171 |
| MAP7 | microtubule-associated protein 7 | -0.0112594 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0104729 |
| HOPX | HOP homeobox | -0.00896915 |
| PEG10 | paternally expressed 10 | -0.00871064 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.0085311 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00827157 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00769725 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00756971 |
| KLF6 | Kruppel-like factor 6 | -0.00755523 |
| PDZD2 | PDZ domain containing 2 | -0.0075141 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.0073037 |
| ZNF395 | zinc finger protein 395 | -0.00726047 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0071873 |
| SFTPA2 | surfactant protein A2 | -0.00702659 |
| TPBG | trophoblast glycoprotein | -0.00695524 |
| BEX1 | brain expressed, X-linked 1 | -0.0069247 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00689345 |
| FOLR1 | folate receptor 1 (adult) | -0.00677444 |
| SFTPD | surfactant protein D | -0.00671374 |
| C4BPA | complement component 4 binding protein, alpha | -0.0066972 |
| CA12 | carbonic anhydrase XII | -0.00665728 |
| STC2 | stanniocalcin 2 | -0.0066513 |
| DNM1L | dynamin 1-like | -0.00662936 |
| CALML3 | calmodulin-like 3 | -0.00654149 |
| REEP1 | receptor accessory protein 1 | -0.00652768 |
| TLR4 | toll-like receptor 4 | -0.0065247 |
| ITM2A | integral membrane protein 2A | -0.00649653 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00649156 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00639451 |
| TRAM1 | translocation associated membrane protein 1 | -0.00638621 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00623758 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00610018 |
| SFTPB | surfactant protein B | -0.00605253 |
| CHEK1 | checkpoint kinase 1 | -0.0060266 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00601515 |
| EXOC5 | exocyst complex component 5 | -0.00600888 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00595186 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00591081 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00579443 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00567734 |
| REXO2 | RNA exonuclease 2 | -0.00567653 |
| OBSL1 | obscurin-like 1 | -0.00565721 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00564282 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00563023 |
| GAL | galanin/GMAP prepropeptide | -0.0055858 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00557991 |
| PCLAF | PCNA clamp associated factor | -0.00557879 |
| PTHLH | parathyroid hormone-like hormone | -0.00555884 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00554673 |
| NPTX2 | neuronal pentraxin II | -0.0055427 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.0055308 |
| PDGFC | platelet derived growth factor C | -0.005506 |
| CLC | Charcot-Leyden crystal galectin | -0.00537976 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00536648 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00534648 |
| DSTN | destrin (actin depolymerizing factor) | -0.00534053 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00532715 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00526587 |
| CREBZF | CREB/ATF bZIP transcription factor | -0.00524786 |
| SFTPC | surfactant protein C | -0.00523448 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00522765 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00518853 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -0.00517064 |
| RDX | radixin | -0.0051438 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00513702 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00512491 |
| PON3 | paraoxonase 3 | -0.00512078 |
| S100A10 | S100 calcium binding protein A10 | -0.00511327 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00510531 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00508868 |
| CRYAB | crystallin, alpha B | -0.00506895 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00506177 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00504225 |
| RNF24 | ring finger protein 24 | -0.00503059 |
| RBM34 | RNA binding motif protein 34 | -0.00502803 |
| SIRT3 | sirtuin 3 | -0.00500967 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00497231 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00496779 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00494315 |
| PFDN4 | prefoldin subunit 4 | -0.00493552 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.00492923 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00492748 |
| ATP10D | ATPase, class V, type 10D | -0.00492041 |
| TRIM44 | tripartite motif containing 44 | -0.00491869 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00491752 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00491242 |
| BEX4 | brain expressed, X-linked 4 | -0.0049121 |
| IL32 | interleukin 32 | -0.00489056 |
| PLS3 | plastin 3 | -0.00488992 |
| DSG1 | desmoglein 1 | -0.00485035 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00482428 |
| ADM | adrenomedullin | -0.00481564 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.00479856 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | -0.00477769 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00477349 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00476765 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00475924 |
| HEATR1 | HEAT repeat containing 1 | -0.00474846 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00474354 |
| TMEM230 | transmembrane protein 230 | -0.00473307 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00472531 |
| BMP2 | bone morphogenetic protein 2 | -0.00471747 |
| TTN | titin | -0.00471561 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00471467 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.00471354 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00470739 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00467523 |
| RBM4 | RNA binding motif protein 4 | -0.00467163 |
| PGC | progastricsin (pepsinogen C) | -0.00466164 |
| WT1 | Wilms tumor 1 | -0.00465665 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00465582 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 | -0.00465339 |
| ELANE | elastase, neutrophil expressed | -0.00464545 |
| NPR3 | natriuretic peptide receptor 3 | -0.00463977 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00463347 |
| WBP5 | WW domain binding protein 5 | -0.00462561 |
| ZBED5 | zinc finger, BED-type containing 5 | -0.00461781 |
| LOXL2 | lysyl oxidase-like 2 | -0.00460269 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00459847 |
| STK32B | serine/threonine kinase 32B | -0.00458908 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0045814 |
| TNNC1 | troponin C type 1 (slow) | -0.00457611 |
| UTRN | utrophin | -0.00457569 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.00457283 |
| PRNP | prion protein | -0.00455545 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00455116 |
| SYT1 | synaptotagmin I | -0.00451732 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00451716 |
| POSTN | periostin, osteoblast specific factor | -0.00447958 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00447111 |
| RTN2 | reticulon 2 | -0.00445649 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00445617 |
| STK17A | serine/threonine kinase 17a | -0.00444933 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00443635 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00443198 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00441089 |
| ATP5MG | ATP synthase membrane subunit g | -0.00440986 |
| ZNRD2 | zinc ribbon domain containing 2 | -0.00439153 |
| ENSA | endosulfine alpha | -0.00438741 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00436202 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00434489 |
| RBPMS | RNA binding protein with multiple splicing | -0.00434217 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | -0.00431269 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.00431066 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00430849 |
| EXPH5 | exophilin 5 | -0.00429071 |
| MYO1B | myosin IB | -0.0042901 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00427961 |
| KLK5 | kallikrein-related peptidase 5 | -0.00427901 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0042633 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00426146 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.0042559 |
| GMFG | glia maturation factor, gamma | -0.004245 |
| DSC1 | desmocollin 1 | -0.00418378 |
| MOCS2 | molybdenum cofactor synthesis 2 | -0.00418348 |
| MX1 | MX dynamin-like GTPase 1 | -0.00416096 |
| XIC | X chromosome inactivation center | -0.00416031 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00415989 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00415981 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00415869 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0041437 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00412499 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00411566 |
| KRT7 | keratin 7, type II | -0.00411059 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.00410751 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.00410202 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00410181 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00409704 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | -0.00409279 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.0040913 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.00408757 |
| ZNF302 | zinc finger protein 302 | -0.00408235 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00408122 |
| TMEM204 | transmembrane protein 204 | -0.00407526 |
| ZNF160 | zinc finger protein 160 | -0.00407161 |
| PLIN2 | perilipin 2 | -0.00407125 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00406466 |
| LIMA1 | LIM domain and actin binding 1 | -0.00405683 |
| BFAR | bifunctional apoptosis regulator | -0.00403467 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00402065 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00401171 |
| MAP2 | microtubule-associated protein 2 | -0.00400861 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -0.00400088 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0039955 |
| TOX | thymocyte selection-associated high mobility group box | -0.00398924 |
| BTG3 | BTG family, member 3 | -0.00397718 |
| BANF1 | barrier to autointegration factor 1 | -0.00397316 |
| SMYD2 | SET and MYND domain containing 2 | -0.00397097 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00396694 |
| NKX2-1 | NK2 homeobox 1 | -0.0039608 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.00396044 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00395912 |
| ANXA10 | annexin A10 | -0.00395256 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0039467 |
| MPO | myeloperoxidase | -0.00394172 |
| CNN3 | calponin 3, acidic | -0.00393613 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | -0.00392671 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.00392427 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00392414 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.00391367 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.00390872 |
| TFRC | transferrin receptor | -0.00390231 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00390118 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00389963 |
| USP47 | ubiquitin specific peptidase 47 | -0.00388982 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.00388672 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.00387336 |
| IFI44L | interferon-induced protein 44-like | -0.00387128 |
| TRIB3 | tribbles pseudokinase 3 | -0.003867 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | -0.00386526 |
| PHIP | pleckstrin homology domain interacting protein | -0.00385963 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00385774 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.003855 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00385321 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.00384188 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00383479 |
| H2AFV | H2A histone family, member V | -0.00383328 |
| RNFT1 | ring finger protein, transmembrane 1 | -0.00383048 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | -0.00382349 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.00381842 |
| SNAP29 | synaptosomal-associated protein, 29kDa | -0.00381466 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.00381047 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | -0.00380898 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -0.0038089 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00380532 |
| RAB1A | RAB1A, member RAS oncogene family | -0.00380289 |
| IFI44 | interferon-induced protein 44 | -0.00380142 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00378146 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00377307 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | -0.00376453 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00375238 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.00373929 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00373599 |
| GGCX | gamma-glutamyl carboxylase | -0.00373564 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00373346 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00372977 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00372916 |
| NUCB2 | nucleobindin 2 | -0.00372846 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00372573 |
| GTF2I | general transcription factor IIi | -0.00372327 |
| TMEM258 | transmembrane protein 258 | -0.00372192 |
| CD151 | CD151 molecule (Raph blood group) | -0.00371945 |
| CEP57 | centrosomal protein 57kDa | -0.00371551 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | -0.00370755 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00370736 |
| ADK | adenosine kinase | -0.00370473 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.0037026 |
