DROPERIDOL Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. (Chemical Entities of Biological Interest Ontology, CHEBI_4717)
External Link https://dgidb.org/results?searchType=drug&searchTerms=DROPERIDOL
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Genes

5 interacting proteins for the DROPERIDOL drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
DRD2 dopamine receptor D2 0.190746
DRD4 dopamine receptor D4 0.134005
DRD3 dopamine receptor D3 0.090482
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.0485615
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.0173263