DSCAM Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Down syndrome cell adhesion molecule|This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012] (NCBI Entrez Gene Database, 1826)
External Link https://ncbi.nlm.nih.gov/gene/1826
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Genes

500 genes differentially expressed following the DSCAM gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SEPP1 selenoprotein P, plasma, 1 0.0159576
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0152986
PRDX2 peroxiredoxin 2 0.0147441
OLFM1 olfactomedin 1 0.0144841
OLFM4 olfactomedin 4 0.0144749
HBB hemoglobin, beta 0.0137152
ZBTB18 zinc finger and BTB domain containing 18 0.013442
GET1 guided entry of tail-anchored proteins factor 1 0.0130351
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0126362
NTS neurotensin 0.0122411
TSPAN7 tetraspanin 7 0.0118406
MYO5C myosin VC 0.0109746
RAD23B RAD23 homolog B (S. cerevisiae) 0.010777
FBXO5 F-box protein 5 0.0105594
RPA3 replication protein A3, 14kDa 0.0105218
CXCL6 chemokine (C-X-C motif) ligand 6 0.0103794
PBK PDZ binding kinase 0.0103611
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.0102267
SAP30 Sin3A-associated protein, 30kDa 0.0102216
SPARCL1 SPARC-like 1 (hevin) 0.0101504
PBX1 pre-B-cell leukemia homeobox 1 0.0101312
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0100176
AGR2 anterior gradient 2 0.00979204
THYN1 thymocyte nuclear protein 1 0.00968867
FGFR3 fibroblast growth factor receptor 3 0.0096261
PPA2 pyrophosphatase (inorganic) 2 0.00955526
GLUL glutamate-ammonia ligase 0.00951118
SPC25 SPC25, NDC80 kinetochore complex component 0.00945844
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00944378
XPO7 exportin 7 0.00940307
DUT deoxyuridine triphosphatase 0.00935378
TFF3 trefoil factor 3 (intestinal) 0.00931962
COPS4 COP9 signalosome subunit 4 0.00927927
CDCA4 cell division cycle associated 4 0.00925692
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00922332
ACAT2 acetyl-CoA acetyltransferase 2 0.00921824
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.00919895
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00912764
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00907411
CP ceruloplasmin (ferroxidase) 0.00905392
TXNDC9 thioredoxin domain containing 9 0.00905313
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.0090503
SUB1 SUB1 homolog (S. cerevisiae) 0.00901154
AQP4 aquaporin 4 0.00898885
PLSCR4 phospholipid scramblase 4 0.00891788
TMSB15A thymosin beta 15a 0.0089035
PLAT plasminogen activator, tissue 0.00889683
TMEM231 transmembrane protein 231 0.00885257
CCND2 cyclin D2 0.0088446
FGF13 fibroblast growth factor 13 0.00882791
LMNB1 lamin B1 0.00880138
NLGN4X neuroligin 4, X-linked 0.00876602
ARL3 ADP-ribosylation factor-like 3 0.00873991
VBP1 von Hippel-Lindau binding protein 1 0.00873215
DPY19L4 dpy-19-like 4 (C. elegans) 0.00872888
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00869981
CLU clusterin 0.00869863
ABHD10 abhydrolase domain containing 10 0.00864783
FABP1 fatty acid binding protein 1, liver 0.00862202
BIRC5 baculoviral IAP repeat containing 5 0.00859314
GCA grancalcin, EF-hand calcium binding protein 0.00858713
CETN2 centrin, EF-hand protein, 2 0.00851397
MSMO1 methylsterol monooxygenase 1 0.00848689
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00847697
OIP5 Opa interacting protein 5 0.00847534
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00844574
CPVL carboxypeptidase, vitellogenic-like 0.00844356
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00841433
ETNK1 ethanolamine kinase 1 0.00839139
CXCL12 chemokine (C-X-C motif) ligand 12 0.00838518
COPS7A COP9 signalosome subunit 7A 0.00838004
METRN meteorin, glial cell differentiation regulator 0.00833361
ELOVL6 ELOVL fatty acid elongase 6 0.00831221
DCXR dicarbonyl/L-xylulose reductase 0.00829122
GSTM3 glutathione S-transferase mu 3 (brain) 0.00827826
PLPBP pyridoxal phosphate binding protein 0.00826898
CCNF cyclin F 0.00825609
CADPS2 Ca++-dependent secretion activator 2 0.00825562
TMX1 thioredoxin-related transmembrane protein 1 0.00819722
FBXO11 F-box protein 11 0.00815779
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00815625
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00815251
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0081439
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00812684
SPA17 sperm autoantigenic protein 17 0.00812188
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.00810844
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00809742
COMMD8 COMM domain containing 8 0.00809326
ERLIN2 ER lipid raft associated 2 0.00806564
NSL1 NSL1, MIS12 kinetochore complex component 0.00806282
FCGBP Fc fragment of IgG binding protein 0.00806226
MLF1 myeloid leukemia factor 1 0.0080586
CFH complement factor H 0.00804442
GEMIN2 gem (nuclear organelle) associated protein 2 0.0080291
SDC2 syndecan 2 0.00801279
B3GNT1 0.00800151
GPM6A glycoprotein M6A 0.00799836
RAD51AP1 RAD51 associated protein 1 0.00798707
NRN1 neuritin 1 0.00797729
PSRC1 proline/serine-rich coiled-coil 1 0.00797453
CCDC47 coiled-coil domain containing 47 0.00786141
INSIG1 insulin induced gene 1 0.00786072
TMEM100 transmembrane protein 100 0.00784966
ATF1 activating transcription factor 1 0.00781267
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00779985
LYZ lysozyme 0.00776142
CLCA1 chloride channel accessory 1 0.00775415
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00775007
TRMT5 tRNA methyltransferase 5 0.00774775
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00773908
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00773215
MOCS2 molybdenum cofactor synthesis 2 0.00772868
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00772183
COMMD10 COMM domain containing 10 0.00768739
CDC42 cell division cycle 42 0.00765048
CDKN3 cyclin-dependent kinase inhibitor 3 0.0076462
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00763905
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00763699
THAP12 THAP domain containing 12 0.00762333
PXMP2 peroxisomal membrane protein 2, 22kDa 0.00761503
ICMT isoprenylcysteine carboxyl methyltransferase 0.00760654
NEK2 NIMA-related kinase 2 0.00760067
DTWD1 DTW domain containing 1 0.00759837
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00759208
EFCAB11 EF-hand calcium binding domain 11 0.00759115
HMGB1 high mobility group box 1 0.00758357
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.0075742
KIF18B kinesin family member 18B 0.00753246
DEPDC1 DEP domain containing 1 0.00753028
PTCH1 patched 1 0.00752215
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00749502
LBR lamin B receptor 0.0074717
EPS8 epidermal growth factor receptor pathway substrate 8 0.00746504
CENPX centromere protein X 0.00745898
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00744858
KLHL23 kelch-like family member 23 0.00742298
RSL24D1 ribosomal L24 domain containing 1 0.0074195
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.00738479
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00737807
CHN2 chimerin 2 0.00736196
NRGN neurogranin (protein kinase C substrate, RC3) 0.00735884
ZNF443 zinc finger protein 443 0.00735762
DHCR7 7-dehydrocholesterol reductase 0.00731789
PRKD3 protein kinase D3 0.00731095
AZF1 azoospermia factor 1 0.00729607
PARPBP PARP1 binding protein 0.00728956
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00727604
ZNF226 zinc finger protein 226 0.00727482
EAPP E2F-associated phosphoprotein 0.00726658
FBXO3 F-box protein 3 0.00725636
COX7B cytochrome c oxidase subunit VIIb 0.00725549
IL17RB interleukin 17 receptor B 0.00725222
PCP4 Purkinje cell protein 4 0.00724296
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00724016
RAB40B RAB40B, member RAS oncogene family 0.00723659
RMI1 RecQ mediated genome instability 1 0.00721569
FOXG1 forkhead box G1 0.00720489
NIPSNAP2 nipsnap homolog 2 0.00720156
UGCG UDP-glucose ceramide glucosyltransferase 0.00717004
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00716532
LPAR1 lysophosphatidic acid receptor 1 0.00716473
HAT1 histone acetyltransferase 1 0.00714913
METTL7A methyltransferase like 7A 0.00714566
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00713345
ERH enhancer of rudimentary homolog (Drosophila) 0.00712842
CDCA3 cell division cycle associated 3 0.00712499
CST3 cystatin C 0.00711439
DAXX death-domain associated protein 0.00708581
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00708249
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00706817
SLC35A5 solute carrier family 35, member A5 0.00706328
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00705453
TFDP1 transcription factor Dp-1 0.00705064
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00704694
SEPHS1 selenophosphate synthetase 1 0.00702627
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0070094
ASF1B anti-silencing function 1B histone chaperone 0.0069986
PMP2 peripheral myelin protein 2 0.00699728
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00698865
HMGN5 high mobility group nucleosome binding domain 5 0.00697834
RBBP8 retinoblastoma binding protein 8 0.00696983
RAPSN receptor-associated protein of the synapse 0.00696572
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00696334
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00696011
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00695622
GPM6B glycoprotein M6B 0.00694837
NFIB nuclear factor I/B 0.00693738
LGALS13 lectin, galactoside-binding, soluble, 13 0.00693394
CHN1 chimerin 1 0.00692628
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00691141
ACYP2 acylphosphatase 2, muscle type 0.00690536
C8ORF4 chromosome 8 open reading frame 4 0.0069021
PRPF4 pre-mRNA processing factor 4 0.00688912
SPTSSA serine palmitoyltransferase, small subunit A 0.00687909
NPM3 nucleophosmin/nucleoplasmin 3 0.00687628
SCRG1 stimulator of chondrogenesis 1 0.00687449
FAM169A family with sequence similarity 169, member A 0.00685907
CDC7 cell division cycle 7 0.00684744
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00681073
TMEM38B transmembrane protein 38B 0.00677086
KIF15 kinesin family member 15 0.00676899
ANOS1 anosmin 1 0.0067679
HP haptoglobin 0.00676627
ECT2 epithelial cell transforming 2 0.00676467
ECI2 enoyl-CoA delta isomerase 2 0.00674166
SELENBP1 selenium binding protein 1 0.00670133
SAC3D1 SAC3 domain containing 1 0.0066928
RBBP4 retinoblastoma binding protein 4 0.00668661
PLP1 proteolipid protein 1 0.00667437
LIG1 ligase I, DNA, ATP-dependent 0.00667399
ADGRL3 adhesion G protein-coupled receptor L3 0.00665846
CTSK cathepsin K 0.00665477
HPF1 histone PARylation factor 1 0.00664739
IFT52 intraflagellar transport 52 0.00664577
EFNB3 ephrin-B3 0.00664316
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.00664147
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00661742
TRAPPC2L trafficking protein particle complex 2-like 0.00661316
SEC23A Sec23 homolog A (S. cerevisiae) 0.00660258
ALDOC aldolase C, fructose-bisphosphate 0.00657415
HMGB3 high mobility group box 3 0.00657353
AMD1 adenosylmethionine decarboxylase 1 0.0065704
NUSAP1 nucleolar and spindle associated protein 1 0.00657011
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00656529
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) 0.00655823
SPON1 spondin 1, extracellular matrix protein 0.00655596
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00655277
CCNA2 cyclin A2 0.00654161
LZTFL1 leucine zipper transcription factor-like 1 0.00651721
TTC33 tetratricopeptide repeat domain 33 0.00651067
KIF20A kinesin family member 20A 0.00650677
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.00650276
CLIC2 chloride intracellular channel 2 0.00649237
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.0064796
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00647526
RAB20 RAB20, member RAS oncogene family 0.00647429
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.00646992
VRK1 vaccinia related kinase 1 0.00645956
VCAM1 vascular cell adhesion molecule 1 0.00645451
NME5 NME/NM23 family member 5 0.00644467
STMN1 stathmin 1 0.00641201
CLCA4 chloride channel accessory 4 0.00640367
LAGE3 L antigen family, member 3 0.00637418
ARHGAP19 Rho GTPase activating protein 19 0.00637315
SELENOW selenoprotein W 0.00636546
DCK deoxycytidine kinase 0.00636187
NCAPD3 non-SMC condensin II complex, subunit D3 0.00634919
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00633503
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00632865
MYT1L myelin transcription factor 1-like 0.00632496

decreased expression

Symbol Name Standardized Value
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0204091
HSPB1 heat shock 27kDa protein 1 -0.0177944
HSPA1A heat shock 70kDa protein 1A -0.0171652
IFI6 interferon, alpha-inducible protein 6 -0.0169248
MVP major vault protein -0.0168233
KRT14 keratin 14, type I -0.0165693
DSP desmoplakin -0.0156931
IFI27 interferon, alpha-inducible protein 27 -0.0155571
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.0154215
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0154078
AQP3 aquaporin 3 (Gill blood group) -0.0145134
CCN2 cellular communication network factor 2 -0.0144856
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0144194
COG7 component of oligomeric golgi complex 7 -0.0142994
IFI44L interferon-induced protein 44-like -0.0142261
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0139253
MX1 MX dynamin-like GTPase 1 -0.013925
PERP PERP, TP53 apoptosis effector -0.0139056
CRYAB crystallin, alpha B -0.0133281
ECM1 extracellular matrix protein 1 -0.0131661
HMOX1 heme oxygenase 1 -0.0130075
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.0128868
ISG15 ISG15 ubiquitin-like modifier -0.0126687
GADD45A growth arrest and DNA-damage-inducible, alpha -0.012458
ADM adrenomedullin -0.0123682
KRT16 keratin 16, type I -0.0120787
HIST1H2BD histone cluster 1, H2bd -0.0120334
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0119922
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0119467
TUFT1 tuftelin 1 -0.011863
SLC38A1 solute carrier family 38, member 1 -0.0117765
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.0115577
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0114778
PDZK1IP1 PDZK1 interacting protein 1 -0.0113539
IRF7 interferon regulatory factor 7 -0.0113064
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.0113036
IL32 interleukin 32 -0.0112152
TUBA4A tubulin, alpha 4a -0.0110851
NDRG1 N-myc downstream regulated 1 -0.0110816
INHBA inhibin, beta A -0.0110109
KRT7 keratin 7, type II -0.0109395
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.0108737
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.0107539
LAMB3 laminin, beta 3 -0.0105476
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.01052
IFI44 interferon-induced protein 44 -0.0104536
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.010452
EPS8L2 EPS8-like 2 -0.0104498
IER5 immediate early response 5 -0.0104021
STXBP2 syntaxin binding protein 2 -0.0102948
TYMP thymidine phosphorylase -0.0102033
HSPB8 heat shock 22kDa protein 8 -0.0101437
FN1 fibronectin 1 -0.0101049
COL9A2 collagen, type IX, alpha 2 -0.0100188
INAVA innate immunity activator -0.00973781
SIK1 salt-inducible kinase 1 -0.0097139
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00971323
KANK1 KN motif and ankyrin repeat domains 1 -0.0096562
AKAP12 A kinase (PRKA) anchor protein 12 -0.00964736
RFTN1 raftlin, lipid raft linker 1 -0.00962137
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00958312
ZNF91 zinc finger protein 91 -0.00955694
USP18 ubiquitin specific peptidase 18 -0.00949282
ATF3 activating transcription factor 3 -0.00947637
KLF6 Kruppel-like factor 6 -0.00945833
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00932818
AOC1 amine oxidase, copper containing 1 -0.00932669
GPNMB glycoprotein (transmembrane) nmb -0.00924266
CCN3 cellular communication network factor 3 -0.00919729
S100A11 S100 calcium binding protein A11 -0.00917545
IGF2R insulin-like growth factor 2 receptor -0.00912031
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00910694
CTSA cathepsin A -0.00910109
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00905627
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00904568
CTSD cathepsin D -0.00903813
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.00902594
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00902194
TM4SF1 transmembrane 4 L six family member 1 -0.00901605
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00896034
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00892659
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00891569
MYOF myoferlin -0.00889222
CCL5 chemokine (C-C motif) ligand 5 -0.00887701
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00886026
LAMC2 laminin, gamma 2 -0.00884719
GDF15 growth differentiation factor 15 -0.00884312
AHNAK2 AHNAK nucleoprotein 2 -0.00884049
ITSN2 intersectin 2 -0.00883343
SGK1 serum/glucocorticoid regulated kinase 1 -0.00881394
GGT1 gamma-glutamyltransferase 1 -0.00874524
ISG20 interferon stimulated exonuclease gene 20kDa -0.00873887
TACSTD2 tumor-associated calcium signal transducer 2 -0.00873089
LYPD3 LY6/PLAUR domain containing 3 -0.0087216
TFPI2 tissue factor pathway inhibitor 2 -0.0087137
GSDME gasdermin E -0.00868618
WARS1 tryptophanyl-tRNA synthetase 1 -0.00864826
TGFB1 transforming growth factor, beta 1 -0.00864255
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00862715
AMOTL2 angiomotin like 2 -0.00862523
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00861414
ZMAT3 zinc finger, matrin-type 3 -0.00860014
JUNB jun B proto-oncogene -0.00858514
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00855651
FOSL1 FOS-like antigen 1 -0.00855478
PLXNB2 plexin B2 -0.00853286
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00849152
PEG10 paternally expressed 10 -0.00845158
AKAP9 A kinase (PRKA) anchor protein 9 -0.00844
SP100 SP100 nuclear antigen -0.00843048
STK38 serine/threonine kinase 38 -0.00840067
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0083965
MYH9 myosin, heavy chain 9, non-muscle -0.00833724
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00831946
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00831825
SAMD9 sterile alpha motif domain containing 9 -0.0083154
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00831196
BMP2 bone morphogenetic protein 2 -0.0083105
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00829146
AMDHD2 amidohydrolase domain containing 2 -0.00826605
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.00824338
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00822716
OASL 2'-5'-oligoadenylate synthetase-like -0.00821239
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.00819538
IFIH1 interferon induced with helicase C domain 1 -0.00816814
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00815758
LRRC8D leucine rich repeat containing 8 family, member D -0.00814227
SQSTM1 sequestosome 1 -0.00808421
PFKP phosphofructokinase, platelet -0.00804769
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00799455
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -0.0079859
NAV2 neuron navigator 2 -0.00796851
TNIP1 TNFAIP3 interacting protein 1 -0.00796794
RRAGD Ras-related GTP binding D -0.00796456
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00794159
COL7A1 collagen, type VII, alpha 1 -0.00791823
RBM34 RNA binding motif protein 34 -0.00791494
TAGLN transgelin -0.00790877
STK10 serine/threonine kinase 10 -0.00789746
DUSP1 dual specificity phosphatase 1 -0.00787483
ZFP36 ZFP36 ring finger protein -0.00787147
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00785888
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00784406
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00782689
JPT2 Jupiter microtubule associated homolog 2 -0.00780796
FYN FYN proto-oncogene, Src family tyrosine kinase -0.00778186
PTK2B protein tyrosine kinase 2 beta -0.00776462
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00773147
ZNF394 zinc finger protein 394 -0.00771598
IGFBP6 insulin-like growth factor binding protein 6 -0.00769088
CRCT1 cysteine-rich C-terminal 1 -0.00768919
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00768681
CAPG capping protein (actin filament), gelsolin-like -0.0076672
UPP1 uridine phosphorylase 1 -0.00763736
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00763691
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00763465
HOMER3 homer scaffolding protein 3 -0.00763434
GLS glutaminase -0.00762666
CD37 CD37 molecule -0.0076227
PXDC1 PX domain containing 1 -0.00762078
MX2 MX dynamin-like GTPase 2 -0.0076105
FNDC3B fibronectin type III domain containing 3B -0.00760192
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -0.00757639
SPATA20 spermatogenesis associated 20 -0.00756839
IFI35 interferon-induced protein 35 -0.0075405
HTRA1 HtrA serine peptidase 1 -0.00752462
KRT17 keratin 17, type I -0.00752229
USP47 ubiquitin specific peptidase 47 -0.00750335
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00749675
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00749651
DOCK9 dedicator of cytokinesis 9 -0.00748163
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00746751
BTG2 BTG family, member 2 -0.00744792
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00741247
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00741162
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00740481
NPC1 Niemann-Pick disease, type C1 -0.00735229
SIRPA signal-regulatory protein alpha -0.00734515
CTSL cathepsin L -0.00733257
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00732731
TRIM22 tripartite motif containing 22 -0.0073162
IFRD1 interferon-related developmental regulator 1 -0.00731176
JMJD6 jumonji domain containing 6 -0.00730964
CLTB clathrin, light chain B -0.00730332
DGKA diacylglycerol kinase, alpha 80kDa -0.00729996
FGFR1 fibroblast growth factor receptor 1 -0.00729937
AEBP1 AE binding protein 1 -0.00729095
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00728521
TGFA transforming growth factor, alpha -0.00727752
SNAI2 snail family zinc finger 2 -0.00725718
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00725429
CRYBG1 crystallin beta-gamma domain containing 1 -0.00724229
ADRB2 adrenoceptor beta 2, surface -0.00723166
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00721567
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00720737
TENT5A terminal nucleotidyltransferase 5A -0.00718642
RRAD Ras-related associated with diabetes -0.00714929
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00714624
TRIB1 tribbles pseudokinase 1 -0.00711409
FOSL2 FOS-like antigen 2 -0.0071137
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00710109
C10ORF10 chromosome 10 open reading frame 10 -0.00706984
FXYD5 FXYD domain containing ion transport regulator 5 -0.00706593
HGD homogentisate 1,2-dioxygenase -0.0070359
P3H2 prolyl 3-hydroxylase 2 -0.00702788
VNN1 vanin 1 -0.00700287
PLK3 polo-like kinase 3 -0.00697614
CPM carboxypeptidase M -0.00696595
LBH limb bud and heart development -0.00694711
ADAM10 ADAM metallopeptidase domain 10 -0.00694398
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00693875
KDM6B lysine (K)-specific demethylase 6B -0.00693498
TPM1 tropomyosin 1 (alpha) -0.00692602
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.0069193
CDA cytidine deaminase -0.00691641
TRIP6 thyroid hormone receptor interactor 6 -0.00691389
ABHD4 abhydrolase domain containing 4 -0.00687997
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -0.00687693
TDRD7 tudor domain containing 7 -0.00685984
HECA headcase homolog (Drosophila) -0.00685897
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00684339
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -0.00683275
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -0.00681681
MYO6 myosin VI -0.00680466
CKM creatine kinase, muscle -0.00680143
SMAD7 SMAD family member 7 -0.00679247
LAMA3 laminin, alpha 3 -0.00679023
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00678812
ALAS1 5'-aminolevulinate synthase 1 -0.00678482
PVR poliovirus receptor -0.00678181
LAMP1 lysosomal-associated membrane protein 1 -0.00677594
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.00677243
TMEM45A transmembrane protein 45A -0.00676583
DAPK1 death-associated protein kinase 1 -0.00674685
NEU1 sialidase 1 (lysosomal sialidase) -0.00674474
JAG1 jagged 1 -0.00673012
CTNND1 catenin (cadherin-associated protein), delta 1 -0.00672778
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0067251
FHL2 four and a half LIM domains 2 -0.00671212
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00667001
POSTN periostin, osteoblast specific factor -0.00666074
NAGK N-acetylglucosamine kinase -0.00665177
AKR1C2 aldo-keto reductase family 1, member C2 -0.00664957
ABLIM1 actin binding LIM protein 1 -0.00662197
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00662134
NT5E 5'-nucleotidase, ecto (CD73) -0.00658859
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.00658554
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00656202
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00654778
DUSP10 dual specificity phosphatase 10 -0.00654367