| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.146308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.142537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.128408 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.109307 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104732 |
| HDAC9 | histone deacetylase 9 | 0.0940375 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0891097 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0840044 |
| CDH13 | cadherin 13 | 0.0836233 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0773597 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0732567 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0727746 |
| TPM3 | tropomyosin 3 | 0.0668414 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0658273 |
| CENPF | centromere protein F, 350/400kDa | 0.0642626 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0600303 |
| CALR | calreticulin | 0.0597829 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0585698 |
| SQSTM1 | sequestosome 1 | 0.0574452 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0560617 |
| ASPH | aspartate beta-hydroxylase | 0.052734 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0519994 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0514552 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.049869 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0462056 |
| RND3 | Rho family GTPase 3 | 0.0461697 |
| ANKRD11 | ankyrin repeat domain 11 | 0.046034 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0456325 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0446946 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0424024 |
| COPA | coatomer protein complex, subunit alpha | 0.0421194 |
| NAV2 | neuron navigator 2 | 0.0418421 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0417919 |
| MSN | moesin | 0.0400298 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0397107 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0391761 |
| S100A6 | S100 calcium binding protein A6 | 0.0389598 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0384371 |
| EFNA5 | ephrin-A5 | 0.037634 |
| DSPP | dentin sialophosphoprotein | 0.0374204 |
| FAM107B | family with sequence similarity 107, member B | 0.0370231 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0367661 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.035982 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0353986 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0353369 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0344468 |
| RTN4 | reticulon 4 | 0.0344467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342896 |
| EGFR | epidermal growth factor receptor | 0.0341451 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0340466 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0337654 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0330504 |
| FSTL1 | follistatin-like 1 | 0.0322579 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0319745 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0315153 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0313185 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0308523 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0307662 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0304648 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0302596 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0301205 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0300691 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.029763 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292415 |
| PTK2 | protein tyrosine kinase 2 | 0.0291083 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0289101 |
| AHNAK | AHNAK nucleoprotein | 0.0287849 |
| E2F7 | E2F transcription factor 7 | 0.0287095 |
| TAOK1 | TAO kinase 1 | 0.0284063 |
| CSTB | cystatin B (stefin B) | 0.0283898 |
| VIM | vimentin | 0.0279876 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0276471 |
| DSG2 | desmoglein 2 | 0.0275263 |
| PRKCE | protein kinase C, epsilon | 0.0274035 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.027255 |
| ENO1 | enolase 1, (alpha) | 0.0265386 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0263638 |
| ERBIN | erbb2 interacting protein | 0.0263591 |
| LDHA | lactate dehydrogenase A | 0.0263274 |
| BCL2L1 | BCL2-like 1 | 0.0260814 |
| JMJD1C | jumonji domain containing 1C | 0.0260351 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0258932 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0255295 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0254561 |
| SUCO | SUN domain containing ossification factor | 0.0253254 |
| DST | dystonin | 0.0252521 |
| GLRX | glutaredoxin (thioltransferase) | 0.0251831 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0249672 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0248401 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0247961 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0247341 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0244303 |
| MKI67 | marker of proliferation Ki-67 | 0.0242493 |
| PTMA | prothymosin, alpha | 0.0241939 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0240904 |
| MYADM | myeloid-associated differentiation marker | 0.0238939 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0238776 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0235174 |
| MAP1B | microtubule-associated protein 1B | 0.0234981 |
| RIOK3 | RIO kinase 3 | 0.0234363 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.225536 |
| FBN1 | fibrillin 1 | -0.159578 |
| LOX | lysyl oxidase | -0.13368 |
| THBS2 | thrombospondin 2 | -0.115165 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.109605 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.108756 |
| PODXL | podocalyxin-like | -0.104036 |
| LOXL2 | lysyl oxidase-like 2 | -0.0971209 |
| COL1A2 | collagen, type I, alpha 2 | -0.0956149 |
| TMSB10 | thymosin beta 10 | -0.0949597 |
| COL5A2 | collagen, type V, alpha 2 | -0.0881112 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0864753 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0860684 |
| COL5A1 | collagen, type V, alpha 1 | -0.0840788 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0774091 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.071879 |
| FN1 | fibronectin 1 | -0.0681161 |
| PRSS23 | protease, serine, 23 | -0.0648177 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0633344 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0631049 |
| MX2 | MX dynamin-like GTPase 2 | -0.0595246 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0590639 |
| RIGI | RNA sensor RIG-I | -0.0589844 |
| SUCNR1 | succinate receptor 1 | -0.0536843 |
| HLA-B | major histocompatibility complex, class I, B | -0.0512004 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.048394 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0470309 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0462724 |
| RNF213 | ring finger protein 213 | -0.0455516 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0447491 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0439012 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0433559 |
| NAV1 | neuron navigator 1 | -0.0430885 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0421044 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0419923 |
| COL3A1 | collagen, type III, alpha 1 | -0.0402817 |
| MEIS2 | Meis homeobox 2 | -0.039828 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0375943 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0370877 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0367885 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0364564 |
| HLA-C | major histocompatibility complex, class I, C | -0.0349657 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0345095 |
| AUTS2 | autism susceptibility candidate 2 | -0.0337199 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0334024 |
| TPM1 | tropomyosin 1 (alpha) | -0.0323717 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0322641 |
| GPC6 | glypican 6 | -0.0317427 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0308654 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0306564 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0303828 |
| TNS3 | tensin 3 | -0.0297177 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0297043 |
| JAZF1 | JAZF zinc finger 1 | -0.0296451 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0293969 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0292429 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.029158 |
| PLAT | plasminogen activator, tissue | -0.0289433 |
| CAVIN1 | caveolae associated protein 1 | -0.0288946 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0282133 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0281057 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0272441 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0272164 |
| GLIS3 | GLIS family zinc finger 3 | -0.0271429 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0266255 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0264626 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0260529 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.025982 |
| TAGLN2 | transgelin 2 | -0.0256555 |
| MT1X | metallothionein 1X | -0.0255233 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0251584 |
| IFI44 | interferon-induced protein 44 | -0.0250104 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0246708 |
| FRMD5 | FERM domain containing 5 | -0.0246334 |
| KIFAP3 | kinesin-associated protein 3 | -0.0245862 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0245107 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0242761 |
| WTAP | Wilms tumor 1 associated protein | -0.0242749 |
| SPAG9 | sperm associated antigen 9 | -0.0241841 |
| MT2A | metallothionein 2A | -0.0239789 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0236892 |
| PXDN | peroxidasin | -0.023374 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0232664 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0226808 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.022556 |
| AFAP1 | actin filament associated protein 1 | -0.022022 |
| MXRA5 | matrix-remodelling associated 5 | -0.0219466 |
| ATP13A3 | ATPase type 13A3 | -0.0216715 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0215156 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0215007 |
| ARF1 | ADP-ribosylation factor 1 | -0.0214678 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0213804 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.021044 |
| ZNF217 | zinc finger protein 217 | -0.0210225 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0208801 |
| COL6A2 | collagen, type VI, alpha 2 | -0.020819 |
| ACTN4 | actinin, alpha 4 | -0.0207501 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0207425 |
| TRIM22 | tripartite motif containing 22 | -0.0204959 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0203976 |
