| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.23099 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.210419 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.180685 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.119104 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.101968 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0925204 |
| RRM2 | ribonucleotide reductase M2 | 0.0911903 |
| ADIPOR2 | adiponectin receptor 2 | 0.0798431 |
| VMP1 | vacuole membrane protein 1 | 0.0743239 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0690126 |
| TPI1 | triosephosphate isomerase 1 | 0.0685472 |
| RPS12 | ribosomal protein S12 | 0.0645546 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.057136 |
| HMGA2 | high mobility group AT-hook 2 | 0.0558223 |
| TPM3 | tropomyosin 3 | 0.053329 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0517393 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0515335 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0512975 |
| DST | dystonin | 0.0506164 |
| HDAC9 | histone deacetylase 9 | 0.0478241 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0477048 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0466475 |
| EXOC4 | exocyst complex component 4 | 0.0453748 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0451782 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0446418 |
| RAD51B | RAD51 paralog B | 0.0437698 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0434016 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0432822 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0419347 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.040932 |
| LDHA | lactate dehydrogenase A | 0.0390293 |
| FNIP1 | folliculin interacting protein 1 | 0.0389193 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0384653 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0383154 |
| TUBA1B | tubulin, alpha 1b | 0.0380896 |
| MED13L | mediator complex subunit 13-like | 0.0368547 |
| YAP1 | Yes-associated protein 1 | 0.0365648 |
| CCND1 | cyclin D1 | 0.0361924 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0361279 |
| BRD2 | bromodomain containing 2 | 0.0354063 |
| TENM3 | teneurin transmembrane protein 3 | 0.0353307 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0349989 |
| RPL3 | ribosomal protein L3 | 0.0347827 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.0347755 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0346837 |
| CDK6 | cyclin-dependent kinase 6 | 0.0339501 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0337304 |
| SETD5 | SET domain containing 5 | 0.0335447 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0333567 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0332539 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0330505 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0317927 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0317084 |
| EXOC6B | exocyst complex component 6B | 0.0315681 |
| FTL | ferritin, light polypeptide | 0.0308688 |
| PRDX1 | peroxiredoxin 1 | 0.0308031 |
| PCDH9 | protocadherin 9 | 0.0307078 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0306923 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0303108 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0303 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0300495 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0300214 |
| MKI67 | marker of proliferation Ki-67 | 0.028946 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0285626 |
| RLF | rearranged L-myc fusion | 0.0283923 |
| INTS4 | integrator complex subunit 4 | 0.0281137 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0278989 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0278899 |
| INTS6 | integrator complex subunit 6 | 0.0278442 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0276833 |
| SQSTM1 | sequestosome 1 | 0.0275973 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0272906 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0270167 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0269856 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0268484 |
| USP34 | ubiquitin specific peptidase 34 | 0.0267593 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266699 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0265841 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0263054 |
| EFNA5 | ephrin-A5 | 0.0260095 |
| RPL4 | ribosomal protein L4 | 0.0257888 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0257707 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0255954 |
| JMJD1C | jumonji domain containing 1C | 0.0254646 |
| CLTC | clathrin, heavy chain (Hc) | 0.0254003 |
| NOP58 | NOP58 ribonucleoprotein | 0.0253889 |
| YBX1 | Y box binding protein 1 | 0.0253246 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0251267 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0251039 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0249012 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0247538 |
| RTN4 | reticulon 4 | 0.0246299 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0245823 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0245057 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0241887 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0240227 |
| ERBIN | erbb2 interacting protein | 0.024013 |
| GOLGB1 | golgin B1 | 0.0239259 |
| RPS3 | ribosomal protein S3 | 0.0238646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.154667 |
| AREG | amphiregulin | -0.103799 |
| TMSB10 | thymosin beta 10 | -0.100042 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0982799 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.092921 |
| PTMA | prothymosin, alpha | -0.0792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0583272 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0562727 |
| CLDN1 | claudin 1 | -0.0544876 |
| MGAT4C | MGAT4 family, member C | -0.0514904 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0514749 |
| AHNAK | AHNAK nucleoprotein | -0.0499141 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0494022 |
| NHSL1 | NHS-like 1 | -0.0486501 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0476996 |
| RPL35A | ribosomal protein L35a | -0.0463554 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0435276 |
| ZNF217 | zinc finger protein 217 | -0.0429177 |
| TMEM123 | transmembrane protein 123 | -0.042293 |
| RPL23 | ribosomal protein L23 | -0.0396929 |
| CANX | calnexin | -0.0393109 |
| GNAS | GNAS complex locus | -0.0376632 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0375009 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0368675 |
| RPS27A | ribosomal protein S27a | -0.0367847 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0366256 |
| PCBP2 | poly(rC) binding protein 2 | -0.036372 |
| BCHE | butyrylcholinesterase | -0.0359375 |
| HMGA1 | high mobility group AT-hook 1 | -0.0356826 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0351829 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0329546 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0325755 |
| WDR45B | WD repeat domain 45B | -0.0321422 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0318445 |
| ZNF804A | zinc finger protein 804A | -0.0312493 |
| UBC | ubiquitin C | -0.0305967 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0297619 |
| GCG | glucagon | -0.0286767 |
| YBX3 | Y box binding protein 3 | -0.027728 |
| KLF6 | Kruppel-like factor 6 | -0.0273842 |
| FGF20 | fibroblast growth factor 20 | -0.0272441 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0264795 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0262768 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0260507 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0256992 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0252537 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0252348 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0251854 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0251646 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.024768 |
| VCL | vinculin | -0.0246683 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0244001 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0240291 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0239242 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.023076 |
| RPS24 | ribosomal protein S24 | -0.0229769 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0229683 |
| STAG2 | stromal antigen 2 | -0.0227626 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0227459 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0224144 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0222438 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.022221 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0220128 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0219543 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0215065 |
| HMGB1 | high mobility group box 1 | -0.0213367 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0210493 |
| CAVIN1 | caveolae associated protein 1 | -0.0209216 |
| BTG3 | BTG family, member 3 | -0.0208482 |
| CCNI | cyclin I | -0.0206051 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0203067 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0202961 |
| LDHB | lactate dehydrogenase B | -0.0202649 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0201142 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.020102 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0199367 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0197074 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.0196709 |
| FBXO11 | F-box protein 11 | -0.0194522 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.018949 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0183737 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0182719 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0180776 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0177679 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0177368 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.017553 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0173948 |
| RPLP1 | ribosomal protein, large, P1 | -0.0171005 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0169841 |
| RASA2 | RAS p21 protein activator 2 | -0.016885 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0167755 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0167213 |
| S100A6 | S100 calcium binding protein A6 | -0.0167162 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0166724 |
| RYK | receptor-like tyrosine kinase | -0.0166031 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0165476 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0165296 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0163852 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.016298 |
| KIF5B | kinesin family member 5B | -0.0160178 |
