| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.0966993 |
| LMO7 | LIM domain 7 | 0.0587693 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0575608 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0536881 |
| INTS6 | integrator complex subunit 6 | 0.0532242 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0530317 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0496091 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0463184 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.045383 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0447549 |
| RAI14 | retinoic acid induced 14 | 0.0440647 |
| NAV2 | neuron navigator 2 | 0.0392453 |
| PTK2 | protein tyrosine kinase 2 | 0.0371581 |
| SMAD3 | SMAD family member 3 | 0.0364433 |
| FNIP1 | folliculin interacting protein 1 | 0.0359409 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0352924 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0350784 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0345364 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.032057 |
| HMGA2 | high mobility group AT-hook 2 | 0.0311541 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0310901 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0295898 |
| ASPH | aspartate beta-hydroxylase | 0.0295622 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0262153 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0261918 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0254071 |
| EFNA5 | ephrin-A5 | 0.0252324 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0251086 |
| RNF217 | ring finger protein 217 | 0.0250575 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0230033 |
| FRMD6 | FERM domain containing 6 | 0.0226665 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0218951 |
| RAD51B | RAD51 paralog B | 0.021882 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0214987 |
| SIK3 | SIK family kinase 3 | 0.0212575 |
| ATXN1 | ataxin 1 | 0.021091 |
| BARX2 | BARX homeobox 2 | 0.0207244 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0202124 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0200625 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0200091 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0198415 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0191528 |
| JMJD1C | jumonji domain containing 1C | 0.0189622 |
| GOLGB1 | golgin B1 | 0.0187081 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0184447 |
| FAM107B | family with sequence similarity 107, member B | 0.018435 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0184032 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0183949 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0182998 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0180913 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.017942 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0178813 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0178532 |
| RASAL2 | RAS protein activator like 2 | 0.0174439 |
| CDK6 | cyclin-dependent kinase 6 | 0.0173565 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.017219 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0169003 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0168703 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0167599 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0165304 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0164093 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0163729 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0163208 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0157954 |
| PMM2 | phosphomannomutase 2 | 0.0157263 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0154318 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0154289 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0153681 |
| EXOC4 | exocyst complex component 4 | 0.0146731 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0146232 |
| ANO6 | anoctamin 6 | 0.0140694 |
| MYO9A | myosin IXA | 0.0136204 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0136176 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0135969 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.013595 |
| TPM3 | tropomyosin 3 | 0.0135798 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0135666 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0134947 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0134314 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0134144 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0131515 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0131234 |
| CNTNAP3 | contactin associated protein-like 3 | 0.013111 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0131083 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0129669 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0127846 |
| GPHN | gephyrin | 0.0127239 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.01268 |
| ATM | ATM serine/threonine kinase | 0.0126707 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0126478 |
| MT1E | metallothionein 1E | 0.0124608 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0124034 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0123159 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0122605 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0121474 |
| SETX | senataxin | 0.0120716 |
| USP34 | ubiquitin specific peptidase 34 | 0.0120328 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.01185 |
| FAM219A | family with sequence similarity 219, member A | 0.0118259 |
| SQSTM1 | sequestosome 1 | 0.0118134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.303597 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.184946 |
| NDRG1 | N-myc downstream regulated 1 | -0.146392 |
| FLNB | filamin B, beta | -0.139651 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128803 |
| SULF1 | sulfatase 1 | -0.1057 |
| PTMA | prothymosin, alpha | -0.104023 |
| B2M | beta-2-microglobulin | -0.0833036 |
| CLU | clusterin | -0.0818684 |
| TMSB10 | thymosin beta 10 | -0.0776433 |
| LMNA | lamin A/C | -0.0677879 |
| PODXL | podocalyxin-like | -0.0675639 |
| S100A10 | S100 calcium binding protein A10 | -0.0648952 |
| LDHA | lactate dehydrogenase A | -0.0646849 |
| ENO1 | enolase 1, (alpha) | -0.0635425 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0635156 |
| KRT17 | keratin 17, type I | -0.0630123 |
| POTEF | POTE ankyrin domain family, member F | -0.0628643 |
| RPS21 | ribosomal protein S21 | -0.059843 |
| PGK1 | phosphoglycerate kinase 1 | -0.0572085 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0571215 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0557471 |
| GNAS | GNAS complex locus | -0.0539095 |
| ITGA6 | integrin, alpha 6 | -0.0538454 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0506332 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0486181 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0483303 |
| RBM39 | RNA binding motif protein 39 | -0.0472948 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0464836 |
| ANXA2 | annexin A2 | -0.0446807 |
| PLAT | plasminogen activator, tissue | -0.0442463 |
| IGF2 | insulin-like growth factor 2 | -0.0437184 |
| PKM | pyruvate kinase, muscle | -0.0434924 |
| RPL11 | ribosomal protein L11 | -0.0422653 |
| RPLP2 | ribosomal protein, large, P2 | -0.0417648 |
| BCL2L1 | BCL2-like 1 | -0.0412044 |
| ANLN | anillin, actin binding protein | -0.0399198 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0393952 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0386275 |
| TMSB4X | thymosin beta 4, X-linked | -0.0379641 |
| EMP1 | epithelial membrane protein 1 | -0.0379126 |
| EZR | ezrin | -0.0376021 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0375742 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0375306 |
| S100A6 | S100 calcium binding protein A6 | -0.0374629 |
| MT2A | metallothionein 2A | -0.0366135 |
| S100A11 | S100 calcium binding protein A11 | -0.0356619 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0354489 |
| TAGLN2 | transgelin 2 | -0.0349347 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0340814 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0337978 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330429 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0329549 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0327406 |
| FTL | ferritin, light polypeptide | -0.0325693 |
| ACTN4 | actinin, alpha 4 | -0.0325689 |
| EFHD2 | EF-hand domain family, member D2 | -0.0323215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321906 |
| RPL35A | ribosomal protein L35a | -0.0320255 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0318641 |
| S100A2 | S100 calcium binding protein A2 | -0.0318319 |
| WASF2 | WAS protein family, member 2 | -0.0315692 |
| HLA-B | major histocompatibility complex, class I, B | -0.0310208 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0308902 |
| KRT6A | keratin 6A, type II | -0.0303424 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0300272 |
| AHNAK | AHNAK nucleoprotein | -0.0299513 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0295992 |
| H1-0 | H1.0 linker histone | -0.0295906 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0295321 |
| MECOM | MDS1 and EVI1 complex locus | -0.0295027 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0293698 |
| PFN1 | profilin 1 | -0.0292654 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0289709 |
| S100A9 | S100 calcium binding protein A9 | -0.0287529 |
| RPS19 | ribosomal protein S19 | -0.0285815 |
| GOLGA4 | golgin A4 | -0.0282454 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280202 |
| RPS6 | ribosomal protein S6 | -0.0279342 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0274275 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0271134 |
| CAVIN1 | caveolae associated protein 1 | -0.0269397 |
| FOXO1 | forkhead box O1 | -0.026659 |
| ANXA1 | annexin A1 | -0.0264636 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0264568 |
| CD99 | CD99 molecule | -0.0263714 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026334 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0261277 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0260286 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0260018 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0256646 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0255545 |
| RPL8 | ribosomal protein L8 | -0.0255443 |
| FLNA | filamin A, alpha | -0.0254032 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0248644 |
| PALLD | palladin, cytoskeletal associated protein | -0.024785 |
| NEK7 | NIMA-related kinase 7 | -0.0247359 |
| EGR1 | early growth response 1 | -0.0246334 |
| KRT14 | keratin 14, type I | -0.0242086 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0241804 |
