| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.137824 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.126327 |
| ANXA1 | annexin A1 | 0.0793818 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0751789 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0657454 |
| GDA | guanine deaminase | 0.0621336 |
| ASPH | aspartate beta-hydroxylase | 0.060884 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0607814 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0593144 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.057581 |
| MYOF | myoferlin | 0.0566352 |
| ATXN1 | ataxin 1 | 0.0563133 |
| DSTN | destrin (actin depolymerizing factor) | 0.0561284 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0557484 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0546195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0541817 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0533099 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0530133 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0528999 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0518743 |
| FTL | ferritin, light polypeptide | 0.0493842 |
| EMP1 | epithelial membrane protein 1 | 0.0455476 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0451759 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0449845 |
| TXNRD1 | thioredoxin reductase 1 | 0.0444182 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0437372 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0434896 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0434759 |
| EZR | ezrin | 0.0434706 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0427025 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0414057 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0412185 |
| JMJD1C | jumonji domain containing 1C | 0.0410814 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0410535 |
| FNIP1 | folliculin interacting protein 1 | 0.0403786 |
| VMP1 | vacuole membrane protein 1 | 0.0395804 |
| DSPP | dentin sialophosphoprotein | 0.0395208 |
| TMC5 | transmembrane channel-like 5 | 0.039401 |
| GOLGB1 | golgin B1 | 0.0389777 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0386011 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0385833 |
| SMAD3 | SMAD family member 3 | 0.0385678 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0383883 |
| ENO1 | enolase 1, (alpha) | 0.0367596 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0367133 |
| SNX9 | sorting nexin 9 | 0.0363194 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.036134 |
| SEPTIN9 | septin 9 | 0.0355832 |
| LCN2 | lipocalin 2 | 0.0354333 |
| MCU | mitochondrial calcium uniporter | 0.0353794 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0352828 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336197 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0332514 |
| EFNA5 | ephrin-A5 | 0.0330338 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0328392 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0325676 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0322009 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0321382 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0320103 |
| INTS6 | integrator complex subunit 6 | 0.0317657 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.031661 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.031637 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.031177 |
| KLHL29 | kelch-like family member 29 | 0.0307085 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0302497 |
| BCL2L1 | BCL2-like 1 | 0.0293075 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0291188 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0289817 |
| DST | dystonin | 0.0289507 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0284971 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0284059 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0281016 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0276596 |
| HKDC1 | hexokinase domain containing 1 | 0.0276395 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0275259 |
| HM13 | histocompatibility (minor) 13 | 0.0272148 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0271925 |
| SLMAP | sarcolemma associated protein | 0.0266765 |
| TJP1 | tight junction protein 1 | 0.0263942 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0261819 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0249562 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0249476 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0248973 |
| AHNAK | AHNAK nucleoprotein | 0.0248129 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0247516 |
| LIMA1 | LIM domain and actin binding 1 | 0.0246078 |
| TMF1 | TATA element modulatory factor 1 | 0.0245572 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0244137 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0241433 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0238749 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0237228 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0236037 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0235972 |
| CDK6 | cyclin-dependent kinase 6 | 0.0235864 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0235101 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0233301 |
| RPL4 | ribosomal protein L4 | 0.0230725 |
| SIK3 | SIK family kinase 3 | 0.0229865 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0229494 |
| MYO1E | myosin IE | 0.0228092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.19318 |
| NPSR1 | neuropeptide S receptor 1 | -0.174205 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.154146 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.116414 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0988813 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0893781 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0749847 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0702508 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0573435 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0531781 |
| PTMA | prothymosin, alpha | -0.0499197 |
| RNF213 | ring finger protein 213 | -0.0478326 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0437504 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0430402 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0409781 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0409271 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0371286 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0367488 |
| MUC17 | mucin 17, cell surface associated | -0.0360977 |
| RRBP1 | ribosome binding protein 1 | -0.0354559 |
| S100A10 | S100 calcium binding protein A10 | -0.0351817 |
| INSIG1 | insulin induced gene 1 | -0.0348088 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0341933 |
| GPX2 | glutathione peroxidase 2 | -0.0340668 |
| RPL35A | ribosomal protein L35a | -0.0338779 |
| TFRC | transferrin receptor | -0.033865 |
| LYZ | lysozyme | -0.032753 |
| ITGB4 | integrin, beta 4 | -0.032337 |
| FASN | fatty acid synthase | -0.0316031 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0315437 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0314505 |
| LOC112694756 | uncharaterized LOC112694756 | -0.03117 |
| HLA-C | major histocompatibility complex, class I, C | -0.0309377 |
| MECOM | MDS1 and EVI1 complex locus | -0.029553 |
| ACTG1 | actin gamma 1 | -0.0285779 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0277407 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0276611 |
| CALR | calreticulin | -0.0271968 |
| POTEF | POTE ankyrin domain family, member F | -0.0268097 |
| MSI2 | musashi RNA-binding protein 2 | -0.0266683 |
| EPCAM | epithelial cell adhesion molecule | -0.026596 |
| S100A11 | S100 calcium binding protein A11 | -0.0265699 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0264159 |
| FAT1 | FAT atypical cadherin 1 | -0.0262464 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0260301 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0257473 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0257379 |
| ANLN | anillin, actin binding protein | -0.0250169 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0242394 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0238537 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0237928 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0235918 |
| RBM39 | RNA binding motif protein 39 | -0.0234672 |
| TMSB10 | thymosin beta 10 | -0.0233449 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0231869 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0231837 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0231704 |
| PRSS3 | protease, serine, 3 | -0.0230639 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0228811 |
| GNAS | GNAS complex locus | -0.0224769 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0224069 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0223147 |
| TRIM31 | tripartite motif containing 31 | -0.0220764 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0219856 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0218227 |
| HLA-E | major histocompatibility complex, class I, E | -0.0216815 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0213408 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0212724 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0211009 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0210354 |
| XPO1 | exportin 1 | -0.020974 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0208238 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0207217 |
| RNF43 | ring finger protein 43 | -0.020678 |
| MKI67 | marker of proliferation Ki-67 | -0.0206217 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0206119 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.020327 |
| MUC1 | mucin 1, cell surface associated | -0.020207 |
| S100A6 | S100 calcium binding protein A6 | -0.0201991 |
| PRKCA | protein kinase C, alpha | -0.0201401 |
| ETV6 | ets variant 6 | -0.0199872 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0199182 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0194804 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0194186 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0193156 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0192403 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0191255 |
| GAK | cyclin G associated kinase | -0.0190561 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.0187154 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0187071 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0185251 |
| CCNL1 | cyclin L1 | -0.0184718 |
| RPS24 | ribosomal protein S24 | -0.0183427 |
| SULF2 | sulfatase 2 | -0.018253 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0182523 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0181203 |
| ECT2 | epithelial cell transforming 2 | -0.0181066 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0180405 |
| UNC93A | unc-93 homolog A (C. elegans) | -0.0180214 |
| CBX3 | chromobox homolog 3 | -0.0180131 |
