| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.174425 |
| EXT1 | exostosin glycosyltransferase 1 | 0.116896 |
| LMO7 | LIM domain 7 | 0.0895787 |
| MYO1E | myosin IE | 0.0798074 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0687996 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0626139 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0547882 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0544257 |
| NEBL | nebulette | 0.0496773 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0463133 |
| FAT1 | FAT atypical cadherin 1 | 0.0456777 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0452604 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0449196 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0448277 |
| ASPH | aspartate beta-hydroxylase | 0.0446629 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0441154 |
| MED13 | mediator complex subunit 13 | 0.0427329 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0426086 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0420919 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0420579 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.039793 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0391039 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0378341 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.037822 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0377006 |
| PDZD8 | PDZ domain containing 8 | 0.0358785 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0358072 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0352905 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0341084 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0339179 |
| ATXN1 | ataxin 1 | 0.0333049 |
| SVIL | supervillin | 0.0327345 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0325967 |
| EGFR | epidermal growth factor receptor | 0.0321126 |
| SIK3 | SIK family kinase 3 | 0.0315659 |
| RPL3 | ribosomal protein L3 | 0.0311414 |
| MYO5B | myosin VB | 0.0306764 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0306461 |
| RPL4 | ribosomal protein L4 | 0.0303223 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0294285 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0292133 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0291882 |
| CUX1 | cut-like homeobox 1 | 0.0291496 |
| RIGI | RNA sensor RIG-I | 0.0290009 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0289237 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0283278 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0282902 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0279309 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0276337 |
| GOLGB1 | golgin B1 | 0.0275114 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0268621 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0267529 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0266771 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0265165 |
| INTS6 | integrator complex subunit 6 | 0.0263071 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0262585 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0260261 |
| SQSTM1 | sequestosome 1 | 0.0260076 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0250458 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0248869 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0247639 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0246708 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0243167 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0241482 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.024137 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0237266 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0236503 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.02363 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0236103 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0230071 |
| BRD2 | bromodomain containing 2 | 0.0228879 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.022785 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0227025 |
| KRT8 | keratin 8, type II | 0.0213825 |
| CRY1 | cryptochrome circadian clock 1 | 0.0211001 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0209991 |
| SMAD2 | SMAD family member 2 | 0.020917 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0208756 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0206807 |
| FNIP1 | folliculin interacting protein 1 | 0.020574 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0201468 |
| RPS12 | ribosomal protein S12 | 0.0201399 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0198708 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0198031 |
| DST | dystonin | 0.0195423 |
| USP53 | ubiquitin specific peptidase 53 | 0.019382 |
| TJP1 | tight junction protein 1 | 0.019221 |
| RND3 | Rho family GTPase 3 | 0.0191203 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0187979 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0187973 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0187531 |
| LDHA | lactate dehydrogenase A | 0.0186176 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0180536 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0179062 |
| FAM107B | family with sequence similarity 107, member B | 0.0178823 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0177315 |
| SGMS2 | sphingomyelin synthase 2 | 0.0177116 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.017682 |
| UBC | ubiquitin C | 0.0173592 |
| FBXO11 | F-box protein 11 | 0.0171736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.262666 |
| NPSR1 | neuropeptide S receptor 1 | -0.166736 |
| TMSB10 | thymosin beta 10 | -0.133084 |
| NDRG1 | N-myc downstream regulated 1 | -0.104535 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.103027 |
| ANXA2 | annexin A2 | -0.0944527 |
| TNS4 | tensin 4 | -0.0844284 |
| RPL35A | ribosomal protein L35a | -0.082847 |
| RPS6 | ribosomal protein S6 | -0.0820629 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0790737 |
| FLNB | filamin B, beta | -0.0753497 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0707958 |
| S100A6 | S100 calcium binding protein A6 | -0.0625631 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0603049 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.058047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0579604 |
| ONECUT3 | one cut homeobox 3 | -0.0570816 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0553538 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0538706 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0516919 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0494714 |
| FERMT1 | fermitin family member 1 | -0.0488224 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0486374 |
| ITGA6 | integrin, alpha 6 | -0.0484978 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0483092 |
| EPCAM | epithelial cell adhesion molecule | -0.0471726 |
| ITGB4 | integrin, beta 4 | -0.0462762 |
| TPM4 | tropomyosin 4 | -0.0458488 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0441576 |
| HMGA1 | high mobility group AT-hook 1 | -0.0440108 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436908 |
| PRSS3 | protease, serine, 3 | -0.0424855 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0424522 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0423881 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0422795 |
| FNBP1L | formin binding protein 1-like | -0.0419553 |
| KIF5B | kinesin family member 5B | -0.0400966 |
| MUC17 | mucin 17, cell surface associated | -0.0398497 |
| FAM13A | family with sequence similarity 13, member A | -0.0398319 |
| CALB1 | calbindin 1, 28kDa | -0.0397811 |
| RNF43 | ring finger protein 43 | -0.0395541 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0385898 |
| EZR | ezrin | -0.0385411 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0380799 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0378625 |
| CD46 | CD46 molecule, complement regulatory protein | -0.036373 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0355812 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0350796 |
| RPL34 | ribosomal protein L34 | -0.0346641 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0343009 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0335961 |
| EXOC1 | exocyst complex component 1 | -0.0334848 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0327274 |
| RPL23 | ribosomal protein L23 | -0.0324961 |
| GPHN | gephyrin | -0.03235 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0322831 |
| MLEC | malectin | -0.0320419 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0313064 |
| ACTN4 | actinin, alpha 4 | -0.0309905 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0308718 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0307556 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0306538 |
| GNAS | GNAS complex locus | -0.0305129 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0301824 |
| RPS19 | ribosomal protein S19 | -0.0300566 |
| PIGR | polymeric immunoglobulin receptor | -0.0299523 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0298135 |
| RBM39 | RNA binding motif protein 39 | -0.0293891 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0292926 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0289809 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.028434 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0271677 |
| GOLGA4 | golgin A4 | -0.027064 |
| ZNF292 | zinc finger protein 292 | -0.0262814 |
| WDR45B | WD repeat domain 45B | -0.026078 |
| RREB1 | ras responsive element binding protein 1 | -0.0257882 |
| USP3 | ubiquitin specific peptidase 3 | -0.0257813 |
| RPS24 | ribosomal protein S24 | -0.0257505 |
| INSIG1 | insulin induced gene 1 | -0.0256709 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0256664 |
| NEMF | nuclear export mediator factor | -0.0256412 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0255808 |
| NFIA | nuclear factor I/A | -0.0255327 |
| FOSL1 | FOS-like antigen 1 | -0.0253787 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0253592 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.025164 |
| POTEF | POTE ankyrin domain family, member F | -0.0248257 |
| CBX3 | chromobox homolog 3 | -0.0240949 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0240591 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0239217 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0238528 |
| PGK1 | phosphoglycerate kinase 1 | -0.0237414 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0235319 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0235134 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0232662 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.022646 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0225042 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.022465 |
| RPL9 | ribosomal protein L9 | -0.0223586 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0223326 |
