| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.190422 |
| DST | dystonin | 0.119176 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0938484 |
| HDAC9 | histone deacetylase 9 | 0.0572493 |
| RUNX1 | runt-related transcription factor 1 | 0.0524351 |
| SQSTM1 | sequestosome 1 | 0.0517371 |
| RPS12 | ribosomal protein S12 | 0.0475089 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0459318 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0423438 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0384461 |
| SPAG9 | sperm associated antigen 9 | 0.0382532 |
| FMNL2 | formin-like 2 | 0.0361769 |
| MYOF | myoferlin | 0.0361343 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0360905 |
| FNIP1 | folliculin interacting protein 1 | 0.0355933 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0345691 |
| CAPRIN2 | caprin family member 2 | 0.0345187 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0331008 |
| TXNIP | thioredoxin interacting protein | 0.0318787 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0314317 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0312553 |
| INTS6 | integrator complex subunit 6 | 0.0304825 |
| RPL4 | ribosomal protein L4 | 0.0299305 |
| JMJD1C | jumonji domain containing 1C | 0.0289927 |
| SP100 | SP100 nuclear antigen | 0.0279743 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0276381 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0275607 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0273161 |
| CD44 | CD44 molecule (Indian blood group) | 0.0262909 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0261532 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.025744 |
| LDHA | lactate dehydrogenase A | 0.0254699 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.024831 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0236681 |
| LYST | lysosomal trafficking regulator | 0.0233889 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0233346 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0232586 |
| TP63 | tumor protein p63 | 0.0232274 |
| UBC | ubiquitin C | 0.0231828 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.02272 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0224675 |
| SIK3 | SIK family kinase 3 | 0.0222582 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.021883 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.021415 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0207885 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0205696 |
| BRD2 | bromodomain containing 2 | 0.0204144 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.020398 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0202275 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0199658 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0196575 |
| PRELID2 | PRELI domain containing 2 | 0.019628 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0195434 |
| B2M | beta-2-microglobulin | 0.0193992 |
| AHNAK | AHNAK nucleoprotein | 0.0192842 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0191473 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0191055 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0189684 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0185574 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0184726 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0182625 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0182338 |
| GOLGB1 | golgin B1 | 0.0182022 |
| TPM3 | tropomyosin 3 | 0.0181978 |
| CRY1 | cryptochrome circadian clock 1 | 0.0181619 |
| PTK2 | protein tyrosine kinase 2 | 0.0179215 |
| RAD51B | RAD51 paralog B | 0.0178175 |
| COPA | coatomer protein complex, subunit alpha | 0.0177174 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0176729 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0176127 |
| H1-0 | H1.0 linker histone | 0.0175534 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0175138 |
| CDK13 | cyclin-dependent kinase 13 | 0.0174773 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0174394 |
| EXOC4 | exocyst complex component 4 | 0.0171887 |
| ATM | ATM serine/threonine kinase | 0.017185 |
| HOMER1 | homer scaffolding protein 1 | 0.0169823 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0168943 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0168129 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0166455 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0164434 |
| SFTPA2 | surfactant protein A2 | 0.0162401 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0162251 |
| RPS18 | ribosomal protein S18 | 0.0162155 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0161882 |
| ANKRD36 | ankyrin repeat domain 36 | 0.016087 |
| CTBP2 | C-terminal binding protein 2 | 0.0160814 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.016031 |
| RPS27A | ribosomal protein S27a | 0.0158313 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0157625 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0157186 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0156229 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0154934 |
| ZNF292 | zinc finger protein 292 | 0.0153233 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0152924 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0152448 |
| VEGFC | vascular endothelial growth factor C | 0.0151765 |
| SEC24A | SEC24 family member A | 0.0151653 |
| HLA-E | major histocompatibility complex, class I, E | 0.0147107 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0146872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.217172 |
| MT2A | metallothionein 2A | -0.201779 |
| PTMA | prothymosin, alpha | -0.127757 |
| TMSB10 | thymosin beta 10 | -0.122245 |
| RPL35A | ribosomal protein L35a | -0.0905193 |
| POTEF | POTE ankyrin domain family, member F | -0.0762312 |
| RAI1 | retinoic acid induced 1 | -0.0680321 |
| MT1X | metallothionein 1X | -0.066037 |
| HMGA1 | high mobility group AT-hook 1 | -0.0585519 |
| RPS6 | ribosomal protein S6 | -0.05451 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0517975 |
| ACTG1 | actin gamma 1 | -0.0496437 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0494841 |
| FTL | ferritin, light polypeptide | -0.0487046 |
| TXNRD1 | thioredoxin reductase 1 | -0.0455274 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0417171 |
| EGR1 | early growth response 1 | -0.041299 |
| SRGN | serglycin | -0.0412957 |
| RPL23 | ribosomal protein L23 | -0.0410394 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0402354 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0399999 |
| RBM25 | RNA binding motif protein 25 | -0.0367992 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0367589 |
| RPS19 | ribosomal protein S19 | -0.0364741 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0360491 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0352065 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0343626 |
| CENPF | centromere protein F, 350/400kDa | -0.0339282 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0330243 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0326565 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0325878 |
| MKI67 | marker of proliferation Ki-67 | -0.0322798 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0322788 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0315321 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0306219 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0303108 |
| RPL5 | ribosomal protein L5 | -0.0297825 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0297187 |
| FERMT1 | fermitin family member 1 | -0.0294536 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0290072 |
| CADM2 | cell adhesion molecule 2 | -0.0288572 |
| RPLP1 | ribosomal protein, large, P1 | -0.0277782 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0277337 |
| FOSL1 | FOS-like antigen 1 | -0.0275477 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0271708 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0270225 |
| UPP1 | uridine phosphorylase 1 | -0.0269925 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0269767 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0266061 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0264772 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0264117 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0260635 |
| PFN1 | profilin 1 | -0.0259188 |
| RPL34 | ribosomal protein L34 | -0.0255265 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0246848 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0245927 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0245109 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0241491 |
| FBXO11 | F-box protein 11 | -0.0239415 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0239165 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0237221 |
| YBX3 | Y box binding protein 3 | -0.0237 |
| FLNB | filamin B, beta | -0.0235665 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0232688 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0229534 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0229181 |
| ANXA1 | annexin A1 | -0.022789 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0226588 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0222388 |
| S100A6 | S100 calcium binding protein A6 | -0.0221548 |
| RPS8 | ribosomal protein S8 | -0.0220707 |
| COL5A2 | collagen, type V, alpha 2 | -0.021886 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.021818 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0217369 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0210425 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0207149 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.020645 |
| RPS14 | ribosomal protein S14 | -0.0205106 |
| TMEM41B | transmembrane protein 41B | -0.0204107 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0202222 |
| PODXL | podocalyxin-like | -0.0201599 |
| TPM4 | tropomyosin 4 | -0.0201549 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0200064 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0199824 |
| S100A10 | S100 calcium binding protein A10 | -0.019943 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0196275 |
| S100A11 | S100 calcium binding protein A11 | -0.0194642 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.019183 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0191541 |
| RPS24 | ribosomal protein S24 | -0.0189427 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0188797 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0187918 |
| PGK1 | phosphoglycerate kinase 1 | -0.0186897 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0185528 |
| MT1E | metallothionein 1E | -0.0185176 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0184291 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0180364 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0179655 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0178306 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0177249 |
