| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.112875 |
| CD44 | CD44 molecule (Indian blood group) | 0.112435 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106951 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.100876 |
| STC1 | stanniocalcin 1 | 0.0992725 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0912157 |
| HDAC9 | histone deacetylase 9 | 0.0696552 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0681101 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0645721 |
| JMJD1C | jumonji domain containing 1C | 0.0622146 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0592797 |
| KYNU | kynureninase | 0.0560458 |
| PGK1 | phosphoglycerate kinase 1 | 0.0516674 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0511469 |
| GPC6 | glypican 6 | 0.0500112 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0480298 |
| NAV2 | neuron navigator 2 | 0.047261 |
| ARRDC3 | arrestin domain containing 3 | 0.0462965 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0460694 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0445282 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0443024 |
| ANXA2 | annexin A2 | 0.0439751 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0438261 |
| SNX9 | sorting nexin 9 | 0.0435001 |
| RUNX1 | runt-related transcription factor 1 | 0.0432623 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0431907 |
| ZNF292 | zinc finger protein 292 | 0.042707 |
| TMSB4X | thymosin beta 4, X-linked | 0.0423396 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0419699 |
| UBC | ubiquitin C | 0.0418546 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0412854 |
| SFTPA2 | surfactant protein A2 | 0.0410313 |
| HLA-E | major histocompatibility complex, class I, E | 0.0402743 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.039677 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0393901 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0393445 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0392987 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0391676 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0390722 |
| AHNAK | AHNAK nucleoprotein | 0.0385161 |
| SMAD3 | SMAD family member 3 | 0.038157 |
| RND3 | Rho family GTPase 3 | 0.0376716 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0374984 |
| FNIP1 | folliculin interacting protein 1 | 0.0372462 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0364099 |
| VCAN | versican | 0.0362698 |
| CDCP1 | CUB domain containing protein 1 | 0.0357188 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0351553 |
| OGA | O-GlcNAcase | 0.0349776 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347863 |
| VIM | vimentin | 0.0347524 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.034691 |
| APP | amyloid beta (A4) precursor protein | 0.0344458 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0342118 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.03399 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0337322 |
| SPAG9 | sperm associated antigen 9 | 0.0337282 |
| LDHA | lactate dehydrogenase A | 0.0335147 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0329824 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0327603 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.032666 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0325104 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0324574 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0316584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0312977 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0312574 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0312223 |
| ARFGEF3 | ARFGEF family member 3 | 0.0310713 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0301005 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0291337 |
| TXNIP | thioredoxin interacting protein | 0.02897 |
| IL6ST | interleukin 6 signal transducer | 0.0281797 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0276316 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0273639 |
| PHF21A | PHD finger protein 21A | 0.0272977 |
| PTK2 | protein tyrosine kinase 2 | 0.0272341 |
| CTSB | cathepsin B | 0.0270736 |
| FMNL2 | formin-like 2 | 0.0270711 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0269701 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0269362 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0269199 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0268349 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0267435 |
| SQSTM1 | sequestosome 1 | 0.0265076 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0264229 |
| RNF24 | ring finger protein 24 | 0.0263823 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0261865 |
| CDK19 | cyclin-dependent kinase 19 | 0.0259468 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0259257 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258318 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0257518 |
| SDC4 | syndecan 4 | 0.02574 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0257001 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0254881 |
| CUL4B | cullin 4B | 0.0252034 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0248798 |
| FOXO3 | forkhead box O3 | 0.0248327 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0246959 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0245847 |
| MKI67 | marker of proliferation Ki-67 | 0.0244907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.111015 |
| RPL37A | ribosomal protein L37a | -0.0738318 |
| TMSB10 | thymosin beta 10 | -0.069997 |
| HLA-B | major histocompatibility complex, class I, B | -0.0688451 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0592913 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0588749 |
| RPS12 | ribosomal protein S12 | -0.0583507 |
| FTL | ferritin, light polypeptide | -0.0528374 |
| RPLP2 | ribosomal protein, large, P2 | -0.0430136 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413397 |
| RPS23 | ribosomal protein S23 | -0.0402559 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0394632 |
| RPS3 | ribosomal protein S3 | -0.0389471 |
| VCL | vinculin | -0.0371574 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0365105 |
| RPS29 | ribosomal protein S29 | -0.0340581 |
| RPL9 | ribosomal protein L9 | -0.033852 |
| ACTG1 | actin gamma 1 | -0.0329977 |
| RPS13 | ribosomal protein S13 | -0.0326185 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0295507 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0294848 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0278677 |
| COL1A1 | collagen, type I, alpha 1 | -0.0269859 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0262211 |
| RPS10 | ribosomal protein S10 | -0.0249214 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0247609 |
| RPL31 | ribosomal protein L31 | -0.0239762 |
| FLNA | filamin A, alpha | -0.0238022 |
| NABP1 | nucleic acid binding protein 1 | -0.0237485 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0237246 |
| CTSD | cathepsin D | -0.0233775 |
| RPS19 | ribosomal protein S19 | -0.0232218 |
| RPS8 | ribosomal protein S8 | -0.0227102 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.022073 |
| RPS27A | ribosomal protein S27a | -0.0220016 |
| BICC1 | BicC family RNA binding protein 1 | -0.020861 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0200709 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0198227 |
| TPM1 | tropomyosin 1 (alpha) | -0.0196905 |
| COL5A1 | collagen, type V, alpha 1 | -0.0195071 |
| RPL11 | ribosomal protein L11 | -0.0191361 |
| RPS17 | ribosomal protein S17 | -0.019007 |
| RPL36 | ribosomal protein L36 | -0.0189322 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0188832 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0188391 |
| RPL7A | ribosomal protein L7a | -0.0186355 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0182527 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0181229 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0180977 |
| PALLD | palladin, cytoskeletal associated protein | -0.0179215 |
| RPS24 | ribosomal protein S24 | -0.0175796 |
| RPL38 | ribosomal protein L38 | -0.0174355 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0172025 |
| TENM2 | teneurin transmembrane protein 2 | -0.0169191 |
| CALR | calreticulin | -0.0168565 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0166113 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0163916 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0161767 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0161721 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0156764 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0155405 |
| RPS25 | ribosomal protein S25 | -0.0153691 |
| DHFR | dihydrofolate reductase | -0.0152879 |
| ARF4 | ADP-ribosylation factor 4 | -0.0152249 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0150872 |
| RPL26 | ribosomal protein L26 | -0.014962 |
| INTS6 | integrator complex subunit 6 | -0.014723 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0147129 |
| RPL28 | ribosomal protein L28 | -0.0143678 |
| RAD51B | RAD51 paralog B | -0.0143343 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0142764 |
| TMEM132D | transmembrane protein 132D | -0.0141639 |
| NCKAP5 | NCK-associated protein 5 | -0.0140105 |
| RNF213 | ring finger protein 213 | -0.0138039 |
| RPS11 | ribosomal protein S11 | -0.0137604 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.01352 |
| HMGA1 | high mobility group AT-hook 1 | -0.0135034 |
| CADM1 | cell adhesion molecule 1 | -0.0134944 |
| PCBP2 | poly(rC) binding protein 2 | -0.0134666 |
| RPL36A | ribosomal protein L36a | -0.0133392 |
| RPL19 | ribosomal protein L19 | -0.0133221 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0131151 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0130555 |
| PLXNA3 | plexin A3 | -0.0128056 |
| TENM3 | teneurin transmembrane protein 3 | -0.0127539 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0126637 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0121786 |
| IER3 | immediate early response 3 | -0.0120561 |
| RPL27 | ribosomal protein L27 | -0.0120511 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0120165 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0119621 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0119211 |
| WDR27 | WD repeat domain 27 | -0.0118742 |
| STC2 | stanniocalcin 2 | -0.0118069 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.011798 |
| EXOC4 | exocyst complex component 4 | -0.0116965 |
| PFKP | phosphofructokinase, platelet | -0.0116754 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0116674 |
| WDR1 | WD repeat domain 1 | -0.0113966 |
| RBM39 | RNA binding motif protein 39 | -0.0113926 |
