| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.114354 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.095335 |
| SVIL | supervillin | 0.0898134 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0895998 |
| SMAD3 | SMAD family member 3 | 0.0850529 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0779834 |
| CD44 | CD44 molecule (Indian blood group) | 0.0735143 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0721454 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.067662 |
| JMJD1C | jumonji domain containing 1C | 0.0655109 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0632043 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0611446 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0606318 |
| PTK2 | protein tyrosine kinase 2 | 0.0591144 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0562968 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0552357 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0536421 |
| FNIP1 | folliculin interacting protein 1 | 0.0531988 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0530252 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0510363 |
| RNF145 | ring finger protein 145 | 0.0482396 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0477618 |
| RUNX1 | runt-related transcription factor 1 | 0.0475645 |
| BRD2 | bromodomain containing 2 | 0.0474062 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0472114 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.046179 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0458922 |
| ANO6 | anoctamin 6 | 0.0458895 |
| YAP1 | Yes-associated protein 1 | 0.0453827 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0444071 |
| ENO1 | enolase 1, (alpha) | 0.0435084 |
| RPL4 | ribosomal protein L4 | 0.0431301 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0430597 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0428155 |
| DTNA | dystrobrevin, alpha | 0.0423041 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0420832 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.041611 |
| DIAPH1 | diaphanous-related formin 1 | 0.0412496 |
| DENND4A | DENN/MADD domain containing 4A | 0.0404175 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0403975 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0403207 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0402577 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0399631 |
| E2F7 | E2F transcription factor 7 | 0.0399399 |
| PDE8A | phosphodiesterase 8A | 0.0397448 |
| RIGI | RNA sensor RIG-I | 0.039223 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0389632 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0386506 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0378879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0375839 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0375055 |
| H3-3B | H3.3 histone B | 0.0374714 |
| TXNRD1 | thioredoxin reductase 1 | 0.037262 |
| ANXA1 | annexin A1 | 0.0372299 |
| STK24 | serine/threonine kinase 24 | 0.036454 |
| FMNL2 | formin-like 2 | 0.036217 |
| SDC4 | syndecan 4 | 0.0360638 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0360219 |
| RPL3 | ribosomal protein L3 | 0.0360021 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0359786 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0355499 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0354858 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0352226 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0350892 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0348657 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0345967 |
| CDK6 | cyclin-dependent kinase 6 | 0.0345158 |
| RTN4 | reticulon 4 | 0.0343459 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0336924 |
| OXSR1 | oxidative stress responsive 1 | 0.0336036 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0335999 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0331004 |
| ASPH | aspartate beta-hydroxylase | 0.032871 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0326438 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0324459 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0323865 |
| RAB10 | RAB10, member RAS oncogene family | 0.0323731 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0323088 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0321731 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0321073 |
| ERBIN | erbb2 interacting protein | 0.0317683 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0316841 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0314237 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0313931 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0313641 |
| PRKCA | protein kinase C, alpha | 0.0311779 |
| RPL27A | ribosomal protein L27a | 0.0308143 |
| SP100 | SP100 nuclear antigen | 0.0307048 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0304345 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0304288 |
| OGA | O-GlcNAcase | 0.0303816 |
| HPCAL1 | hippocalcin-like 1 | 0.0303458 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0298151 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0297922 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0295413 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0291431 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0290605 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0289961 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.028965 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0287817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104388 |
| TMSB10 | thymosin beta 10 | -0.0736768 |
| LDHA | lactate dehydrogenase A | -0.0713514 |
| DNER | delta/notch-like EGF repeat containing | -0.0692673 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0645884 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0607114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0553104 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0547539 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0508728 |
| IGF2 | insulin-like growth factor 2 | -0.0505918 |
| NDRG1 | N-myc downstream regulated 1 | -0.050308 |
| PCNX4 | pecanex 4 | -0.0431104 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0423259 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0396405 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0394354 |
| UBB | ubiquitin B | -0.0386492 |
| AFDN | afadin, adherens junction formation factor | -0.0382728 |
| EGR1 | early growth response 1 | -0.0377122 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.036655 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0362485 |
| PHF3 | PHD finger protein 3 | -0.036037 |
| CENPF | centromere protein F, 350/400kDa | -0.0358795 |
| FMN1 | formin 1 | -0.035461 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0350542 |
| POTEF | POTE ankyrin domain family, member F | -0.0348726 |
| GPC6 | glypican 6 | -0.0342826 |
| VCL | vinculin | -0.0335343 |
| RPL35A | ribosomal protein L35a | -0.0334662 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0328528 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0327322 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0320391 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0320171 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0318871 |
| TPM4 | tropomyosin 4 | -0.031788 |
| DEK | DEK proto-oncogene | -0.0317761 |
| PRR16 | proline rich 16 | -0.0315245 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0313318 |
| DENND1A | DENN/MADD domain containing 1A | -0.0312833 |
| SGO2 | shugoshin 2 | -0.0312083 |
| GNAS | GNAS complex locus | -0.0312047 |
| ATM | ATM serine/threonine kinase | -0.0310417 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0308943 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0307487 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0306381 |
| THBS1 | thrombospondin 1 | -0.0305315 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0305068 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0304957 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0304054 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0301529 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0295003 |
| FLNA | filamin A, alpha | -0.0291217 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0285224 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0284336 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0284283 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278097 |
| RBM39 | RNA binding motif protein 39 | -0.0277115 |
| AURKA | aurora kinase A | -0.0273105 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0272862 |
| NKTR | natural killer cell triggering receptor | -0.0272284 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027209 |
| CAVIN1 | caveolae associated protein 1 | -0.0269635 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0268682 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0267944 |
| RPS15 | ribosomal protein S15 | -0.0266917 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0266808 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0265816 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0265134 |
| RPS27A | ribosomal protein S27a | -0.026486 |
| OLA1 | Obg-like ATPase 1 | -0.0259882 |
| MDC1 | mediator of DNA-damage checkpoint 1 | -0.0257831 |
| TPX2 | TPX2, microtubule-associated | -0.0256544 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0255355 |
| MKI67 | marker of proliferation Ki-67 | -0.025438 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0253312 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0253229 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.025309 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0252156 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0250696 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0249025 |
| HJURP | Holliday junction recognition protein | -0.0247195 |
| RNF216 | ring finger protein 216 | -0.0245824 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0243719 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0242669 |
| GPR107 | G protein-coupled receptor 107 | -0.0240623 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0240239 |
| GPATCH8 | G patch domain containing 8 | -0.0239728 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0238333 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0236947 |
| ATG7 | autophagy related 7 | -0.0236922 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0235177 |
| RFX7 | regulatory factor X, 7 | -0.0230992 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0230316 |
| RTN3 | reticulon 3 | -0.0230175 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0229344 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0226655 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0225393 |
| CGGBP1 | CGG triplet repeat binding protein 1 | -0.0225125 |
| RPL31 | ribosomal protein L31 | -0.0224759 |
| CCDC88A | coiled-coil domain containing 88A | -0.0221995 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0221958 |
