| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DT-061 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DT-061_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.176291 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.152268 |
| HMGA2 | high mobility group AT-hook 2 | 0.149174 |
| ASPH | aspartate beta-hydroxylase | 0.13552 |
| EXT1 | exostosin glycosyltransferase 1 | 0.134332 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.115104 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.10175 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.101616 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0996123 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0995397 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0865691 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0757559 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.074397 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0723007 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.069385 |
| EFNA5 | ephrin-A5 | 0.0677584 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0677355 |
| RASAL2 | RAS protein activator like 2 | 0.0660059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0659556 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0631519 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.063115 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0612962 |
| RAI14 | retinoic acid induced 14 | 0.0610269 |
| VCL | vinculin | 0.0583114 |
| INTS6 | integrator complex subunit 6 | 0.0570792 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0562845 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0556661 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.055196 |
| SQSTM1 | sequestosome 1 | 0.0534927 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0525297 |
| STC2 | stanniocalcin 2 | 0.0516239 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0515642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0501819 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0495086 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0468581 |
| GPATCH2L | G patch domain containing 2-like | 0.0461148 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0458309 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0457449 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0453521 |
| ATF6 | activating transcription factor 6 | 0.0452278 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0445141 |
| NTN4 | netrin 4 | 0.0439317 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0436731 |
| ENO1 | enolase 1, (alpha) | 0.0430356 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0427465 |
| LOXL2 | lysyl oxidase-like 2 | 0.0426435 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0425629 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0418607 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0416696 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0413831 |
| ITGA1 | integrin, alpha 1 | 0.0411582 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.04111 |
| PALLD | palladin, cytoskeletal associated protein | 0.0402386 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0397518 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0385583 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0384314 |
| DUSP6 | dual specificity phosphatase 6 | 0.0383506 |
| AHNAK | AHNAK nucleoprotein | 0.0378897 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0377103 |
| PRKCA | protein kinase C, alpha | 0.0371021 |
| MCL1 | myeloid cell leukemia 1 | 0.0369714 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0366868 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0366391 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0364646 |
| CTBP2 | C-terminal binding protein 2 | 0.0364088 |
| S100A10 | S100 calcium binding protein A10 | 0.0359633 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0353502 |
| ATXN1 | ataxin 1 | 0.034376 |
| GLIS3 | GLIS family zinc finger 3 | 0.0343334 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0343236 |
| AEBP2 | AE binding protein 2 | 0.0338975 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0335207 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0334697 |
| EGFR | epidermal growth factor receptor | 0.0332571 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0329151 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0329107 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0328838 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0325919 |
| MAP1B | microtubule-associated protein 1B | 0.0321953 |
| MYO1E | myosin IE | 0.0321381 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0320576 |
| SYT1 | synaptotagmin I | 0.0316147 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0307447 |
| MYOF | myoferlin | 0.0305652 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0304447 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0301875 |
| RND3 | Rho family GTPase 3 | 0.0300338 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0299019 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0298992 |
| FN1 | fibronectin 1 | 0.0297873 |
| PLIN2 | perilipin 2 | 0.029652 |
| GOLGB1 | golgin B1 | 0.0296455 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0296373 |
| SVIL | supervillin | 0.0295987 |
| GPC6 | glypican 6 | 0.0295704 |
| ACTG1 | actin gamma 1 | 0.0294915 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0294797 |
| UBAP2 | ubiquitin associated protein 2 | 0.029383 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0291116 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0289015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.158144 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.128101 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.115704 |
| CENPF | centromere protein F, 350/400kDa | -0.0785554 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0526514 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0523163 |
| RBM25 | RNA binding motif protein 25 | -0.0467889 |
| RBM39 | RNA binding motif protein 39 | -0.0448655 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.044066 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0429992 |
| MKI67 | marker of proliferation Ki-67 | -0.0422497 |
| OGA | O-GlcNAcase | -0.041239 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0401723 |
| RNF145 | ring finger protein 145 | -0.0398673 |
| NEK7 | NIMA-related kinase 7 | -0.0396483 |
| ZNF292 | zinc finger protein 292 | -0.0382159 |
| RPS6 | ribosomal protein S6 | -0.0365582 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.036403 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0355166 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0350097 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0340097 |
| TPR | translocated promoter region, nuclear basket protein | -0.0339026 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0331083 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0325352 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0319439 |
| ANLN | anillin, actin binding protein | -0.0315075 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.030402 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0302301 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0300389 |
| RPL26 | ribosomal protein L26 | -0.0295983 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0293286 |
| ETNK1 | ethanolamine kinase 1 | -0.0283041 |
| OSMR | oncostatin M receptor | -0.0280154 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.0277116 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0272142 |
| PELO | pelota homolog (Drosophila) | -0.0269771 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0267318 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0267203 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0264659 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0264272 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0257814 |
| FTL | ferritin, light polypeptide | -0.0257515 |
| DIAPH3 | diaphanous-related formin 3 | -0.0253031 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0252311 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0252101 |
| XPO1 | exportin 1 | -0.0249473 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0249446 |
| RTN4 | reticulon 4 | -0.0245745 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0244962 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0244752 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0243581 |
| FAM168B | family with sequence similarity 168, member B | -0.0240374 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0239425 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0237162 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0236767 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0236703 |
| NUP58 | nucleoporin 58 | -0.0236385 |
| ZFR | zinc finger RNA binding protein | -0.0234458 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0230821 |
| TNPO1 | transportin 1 | -0.022747 |
| RAB18 | RAB18, member RAS oncogene family | -0.0225933 |
| TPX2 | TPX2, microtubule-associated | -0.0225416 |
| FAF2 | Fas associated factor family member 2 | -0.0225254 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0224105 |
| RPS2 | ribosomal protein S2 | -0.0223203 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0221932 |
| HDGF | hepatoma-derived growth factor | -0.0218965 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.021699 |
| SMOX | spermine oxidase | -0.0215398 |
| ADD3 | adducin 3 (gamma) | -0.0213679 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0212873 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0211337 |
| HMGB3 | high mobility group box 3 | -0.0211077 |
| WDR43 | WD repeat domain 43 | -0.0210673 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0210208 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0209412 |
| TXNRD1 | thioredoxin reductase 1 | -0.0209277 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0206903 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0206902 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0206682 |
| CAB39 | calcium binding protein 39 | -0.0205818 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0205585 |
| AHR | aryl hydrocarbon receptor | -0.0205299 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0204334 |
| TNPO3 | transportin 3 | -0.0204269 |
| HOMER2 | homer scaffolding protein 2 | -0.0203677 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0203058 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0202985 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0201993 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0201604 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0201324 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0200189 |
| NEMF | nuclear export mediator factor | -0.0200176 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0196549 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0195058 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0195036 |
| CENPE | centromere protein E, 312kDa | -0.0194847 |
| ECT2 | epithelial cell transforming 2 | -0.0193742 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0192256 |
| RBM33 | RNA binding motif protein 33 | -0.0190684 |
