| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.159704 |
| MT2A | metallothionein 2A | 0.130514 |
| PLAT | plasminogen activator, tissue | 0.130269 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.120622 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0994362 |
| NAV2 | neuron navigator 2 | 0.0929926 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0836937 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0807333 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0705868 |
| FLNB | filamin B, beta | 0.0647097 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0642296 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0602026 |
| APP | amyloid beta (A4) precursor protein | 0.0585952 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0577753 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0571168 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0561996 |
| PLEC | plectin | 0.0536372 |
| SEPTIN9 | septin 9 | 0.052785 |
| FLNA | filamin A, alpha | 0.0522875 |
| SQSTM1 | sequestosome 1 | 0.0514163 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0495318 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0472307 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0471787 |
| NAV1 | neuron navigator 1 | 0.0469643 |
| C1D | C1D nuclear receptor corepressor | 0.0454973 |
| AUTS2 | autism susceptibility candidate 2 | 0.0448053 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0434774 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0434236 |
| FBN1 | fibrillin 1 | 0.0433939 |
| STC1 | stanniocalcin 1 | 0.0427035 |
| OPTN | optineurin | 0.0426859 |
| NDRG1 | N-myc downstream regulated 1 | 0.0409598 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0408622 |
| PRELID2 | PRELI domain containing 2 | 0.0401364 |
| ATP13A3 | ATPase type 13A3 | 0.0394641 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0380821 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0378067 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0363584 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345684 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0344742 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0342771 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342548 |
| MSN | moesin | 0.0340865 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0339333 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0338052 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0334084 |
| SFTPA2 | surfactant protein A2 | 0.0332918 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.033243 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0331168 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0329477 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0319874 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0318816 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0318065 |
| SMYD3 | SET and MYND domain containing 3 | 0.0316624 |
| PFKP | phosphofructokinase, platelet | 0.0304517 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0304445 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0297099 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.029608 |
| AFDN | afadin, adherens junction formation factor | 0.0293209 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.029165 |
| DST | dystonin | 0.0290515 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0289803 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0288737 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0282545 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0281918 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0280312 |
| VEGFA | vascular endothelial growth factor A | 0.0280027 |
| LOXL2 | lysyl oxidase-like 2 | 0.0277455 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0276438 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0275506 |
| FAM219A | family with sequence similarity 219, member A | 0.0274761 |
| RPS3 | ribosomal protein S3 | 0.0273082 |
| SET | SET nuclear proto-oncogene | 0.0273031 |
| RPL37A | ribosomal protein L37a | 0.0272714 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0271333 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0268247 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0266268 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0264044 |
| PLXNA3 | plexin A3 | 0.026025 |
| SLC22A23 | solute carrier family 22, member 23 | 0.025529 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0254077 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.02538 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0252438 |
| NONO | non-POU domain containing, octamer-binding | 0.0251931 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.025108 |
| RPS12 | ribosomal protein S12 | 0.0250231 |
| GLIS3 | GLIS family zinc finger 3 | 0.0248306 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0248105 |
| YEATS2 | YEATS domain containing 2 | 0.0248017 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0246901 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0245821 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0243296 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0241617 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0240647 |
| TPM3 | tropomyosin 3 | 0.0238157 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0238147 |
| OGA | O-GlcNAcase | 0.0237921 |
| SMAD3 | SMAD family member 3 | 0.0236768 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.023379 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0232116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.283818 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.225096 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.190555 |
| VIM | vimentin | -0.16647 |
| TMSB10 | thymosin beta 10 | -0.124417 |
| S100A10 | S100 calcium binding protein A10 | -0.100921 |
| LOX | lysyl oxidase | -0.0999207 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0928357 |
| FN1 | fibronectin 1 | -0.0869889 |
| MAP1B | microtubule-associated protein 1B | -0.0803751 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0797035 |
| S100A6 | S100 calcium binding protein A6 | -0.075944 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0753091 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0707029 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0695561 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.06918 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0685762 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0666489 |
| LMNA | lamin A/C | -0.0617943 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0596905 |
| CSTB | cystatin B (stefin B) | -0.0593862 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0555296 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0551449 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0550722 |
| CANX | calnexin | -0.0512984 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.049059 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0479449 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0452573 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0437767 |
| DCLK2 | doublecortin-like kinase 2 | -0.0437126 |
| MEIS2 | Meis homeobox 2 | -0.040915 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0405154 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0403756 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0399916 |
| CALR | calreticulin | -0.0392829 |
| MX2 | MX dynamin-like GTPase 2 | -0.0384133 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0378934 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0372957 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0368195 |
| RIGI | RNA sensor RIG-I | -0.0363472 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.035582 |
| ANXA2 | annexin A2 | -0.0346037 |
| PRSS23 | protease, serine, 23 | -0.0336655 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0336555 |
| CAVIN1 | caveolae associated protein 1 | -0.032842 |
| PTMA | prothymosin, alpha | -0.0324795 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0324481 |
| CD99 | CD99 molecule | -0.0323463 |
| SUCNR1 | succinate receptor 1 | -0.0322146 |
| COL3A1 | collagen, type III, alpha 1 | -0.0320971 |
| GNAS | GNAS complex locus | -0.0316319 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.031359 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0310737 |
| IL7R | interleukin 7 receptor | -0.0309433 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0306396 |
| THBS2 | thrombospondin 2 | -0.029906 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0298214 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0295844 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0293479 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.029283 |
| RTN4 | reticulon 4 | -0.0290701 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0290252 |
| S100A4 | S100 calcium binding protein A4 | -0.0285594 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0284616 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0284067 |
| RRBP1 | ribosome binding protein 1 | -0.0278497 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0274998 |
| LRRC17 | leucine rich repeat containing 17 | -0.0268425 |
| FTL | ferritin, light polypeptide | -0.0265511 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0257534 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0255683 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0254221 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0250499 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0249063 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0244985 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0243294 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0242232 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0241511 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0238174 |
| ARF1 | ADP-ribosylation factor 1 | -0.0234133 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0232863 |
| PFN1 | profilin 1 | -0.0232488 |
| SEC61G | Sec61 gamma subunit | -0.0227763 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0227625 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0225334 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0220009 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.021727 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0214291 |
| THY1 | Thy-1 cell surface antigen | -0.0214184 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0208907 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0208747 |
| COL1A1 | collagen, type I, alpha 1 | -0.0207532 |
| MT1X | metallothionein 1X | -0.0207479 |
| TMEM263 | transmembrane protein 263 | -0.0206672 |
| IER3 | immediate early response 3 | -0.0206127 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0204805 |
| CUX1 | cut-like homeobox 1 | -0.0203734 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0202714 |
| TPM4 | tropomyosin 4 | -0.0200583 |
| FAM162A | family with sequence similarity 162, member A | -0.0197239 |
