| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.149278 |
| VIM | vimentin | 0.121672 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0856844 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0715248 |
| RPS12 | ribosomal protein S12 | 0.0694045 |
| RPL37A | ribosomal protein L37a | 0.068204 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0635077 |
| EHBP1 | EH domain binding protein 1 | 0.0580717 |
| PDGFC | platelet derived growth factor C | 0.0564315 |
| RPS3 | ribosomal protein S3 | 0.0551732 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0526494 |
| YAP1 | Yes-associated protein 1 | 0.0525625 |
| RPS6 | ribosomal protein S6 | 0.0464036 |
| RPL31 | ribosomal protein L31 | 0.0399371 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.038166 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0372819 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0371044 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0370024 |
| EGR1 | early growth response 1 | 0.0369999 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0367057 |
| ACTG1 | actin gamma 1 | 0.0355005 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0350609 |
| POTEF | POTE ankyrin domain family, member F | 0.0336826 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.032675 |
| CMIP | c-Maf inducing protein | 0.0304268 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0301838 |
| BCHE | butyrylcholinesterase | 0.0296473 |
| PCDH7 | protocadherin 7 | 0.0291361 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277368 |
| RPL37 | ribosomal protein L37 | 0.0275314 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274007 |
| ANXA1 | annexin A1 | 0.0268538 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0268164 |
| NLGN1 | neuroligin 1 | 0.0267865 |
| RACK1 | receptor for activated C kinase 1 | 0.0266917 |
| RPS8 | ribosomal protein S8 | 0.0263495 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0263094 |
| SETX | senataxin | 0.0262799 |
| RPL35A | ribosomal protein L35a | 0.0261734 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0260999 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0256416 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0253973 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0242439 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0242355 |
| RPL3 | ribosomal protein L3 | 0.0241871 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0240995 |
| RPS27 | ribosomal protein S27 | 0.0234927 |
| RPS17 | ribosomal protein S17 | 0.023432 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0229932 |
| FAT1 | FAT atypical cadherin 1 | 0.0225191 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0222315 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0221736 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0220598 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0220439 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0219956 |
| CALR | calreticulin | 0.0217351 |
| ZNF804A | zinc finger protein 804A | 0.0213978 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.021202 |
| EGFR | epidermal growth factor receptor | 0.0209647 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0207703 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0207502 |
| CUX1 | cut-like homeobox 1 | 0.0202823 |
| HMGA1 | high mobility group AT-hook 1 | 0.0194248 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.019339 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0189266 |
| PRDX1 | peroxiredoxin 1 | 0.0189199 |
| SKIL | SKI-like proto-oncogene | 0.0189104 |
| NAV3 | neuron navigator 3 | 0.0186544 |
| ASPH | aspartate beta-hydroxylase | 0.0186278 |
| ETV6 | ets variant 6 | 0.0186103 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0186004 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0185047 |
| INTS6 | integrator complex subunit 6 | 0.018437 |
| RPL26 | ribosomal protein L26 | 0.0183261 |
| PDCD6 | programmed cell death 6 | 0.0182902 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0182379 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0180566 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0180481 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0179717 |
| EXOC4 | exocyst complex component 4 | 0.0178531 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0178276 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0178195 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0177614 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0176854 |
| VCAN | versican | 0.0175797 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0175117 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0172915 |
| NHSL1 | NHS-like 1 | 0.0171932 |
| NONO | non-POU domain containing, octamer-binding | 0.0170786 |
| CD9 | CD9 molecule | 0.0170526 |
| RPL10A | ribosomal protein L10a | 0.0168501 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0168202 |
| PLEC | plectin | 0.0168115 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0166813 |
| RASAL2 | RAS protein activator like 2 | 0.0166719 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0166434 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.016625 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0165738 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.0161277 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0159308 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.265545 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261697 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.116422 |
| TMSB10 | thymosin beta 10 | -0.0774593 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0628611 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0585049 |
| UBC | ubiquitin C | -0.0541678 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0471487 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0437046 |
| XPO1 | exportin 1 | -0.0432583 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0429764 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.041081 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0409822 |
| KIF5B | kinesin family member 5B | -0.0405854 |
| RPS27A | ribosomal protein S27a | -0.0403726 |
| RTN4 | reticulon 4 | -0.0391987 |
| RPS21 | ribosomal protein S21 | -0.037478 |
| RPL8 | ribosomal protein L8 | -0.0372582 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0362823 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0360033 |
| H1-0 | H1.0 linker histone | -0.0358844 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0354886 |
| EDN1 | endothelin 1 | -0.0347204 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0342984 |
| PCBP2 | poly(rC) binding protein 2 | -0.0332874 |
| RBM25 | RNA binding motif protein 25 | -0.0332391 |
| ZNF292 | zinc finger protein 292 | -0.032873 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0327925 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.030878 |
| TMEM41B | transmembrane protein 41B | -0.0306624 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0306503 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0306405 |
| RPLP2 | ribosomal protein, large, P2 | -0.0306376 |
| FTL | ferritin, light polypeptide | -0.0306319 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0300505 |
| YBX3 | Y box binding protein 3 | -0.0295331 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0292803 |
| GOLGA4 | golgin A4 | -0.0286413 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0280861 |
| RPL34 | ribosomal protein L34 | -0.027871 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0277211 |
| ECT2 | epithelial cell transforming 2 | -0.0276936 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0275644 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0274089 |
| CLDN1 | claudin 1 | -0.0270802 |
| CCND1 | cyclin D1 | -0.0266172 |
| IL6ST | interleukin 6 signal transducer | -0.0265819 |
| RPL23 | ribosomal protein L23 | -0.0262261 |
| RBM27 | RNA binding motif protein 27 | -0.0261881 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0261268 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0260778 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0260092 |
| RPS13 | ribosomal protein S13 | -0.0255824 |
| CEP95 | centrosomal protein 95kDa | -0.0254089 |
| ZNF207 | zinc finger protein 207 | -0.0253802 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0252611 |
| RPS24 | ribosomal protein S24 | -0.0251376 |
| RRM2 | ribonucleotide reductase M2 | -0.0250378 |
| TUBA1B | tubulin, alpha 1b | -0.0249784 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0249515 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0248974 |
| PREPL | prolyl endopeptidase-like | -0.0236295 |
| LMAN1 | lectin, mannose-binding, 1 | -0.023458 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0234099 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0233116 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0231509 |
| TMEM123 | transmembrane protein 123 | -0.0229736 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0229489 |
| OGA | O-GlcNAcase | -0.0228882 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0228427 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.022821 |
| RPLP0 | ribosomal protein, large, P0 | -0.0226917 |
| TNPO1 | transportin 1 | -0.0222881 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0220578 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0220297 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0218651 |
| CPOX | coproporphyrinogen oxidase | -0.0215081 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.021431 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0213849 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0213643 |
| USP34 | ubiquitin specific peptidase 34 | -0.0213311 |
| SEPTIN7 | septin 7 | -0.0211496 |
| S100A9 | S100 calcium binding protein A9 | -0.0211104 |
| R3HDM1 | R3H domain containing 1 | -0.0210837 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0205834 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0205672 |
| RPL38 | ribosomal protein L38 | -0.0203968 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0203138 |
| USP53 | ubiquitin specific peptidase 53 | -0.0201255 |
| BTG3 | BTG family, member 3 | -0.0198361 |
| TPX2 | TPX2, microtubule-associated | -0.0198329 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0198261 |
| CCNI | cyclin I | -0.0196963 |
| ZNF217 | zinc finger protein 217 | -0.0196887 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0196745 |
| MKI67 | marker of proliferation Ki-67 | -0.0194966 |
| PTMA | prothymosin, alpha | -0.0193899 |
| EPHA6 | EPH receptor A6 | -0.0192864 |
| CBX3 | chromobox homolog 3 | -0.0192806 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0192219 |
