| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LPIN1 | lipin 1 | 0.118352 |
| FMN1 | formin 1 | 0.0935008 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0638917 |
| LSAMP | limbic system-associated membrane protein | 0.0615651 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0577249 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0558208 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0439849 |
| HSPA8 | heat shock 70kDa protein 8 | 0.043067 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0409044 |
| RNF213 | ring finger protein 213 | 0.0392311 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0383428 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0382936 |
| MSI2 | musashi RNA-binding protein 2 | 0.0376623 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0343832 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0338859 |
| RPL3 | ribosomal protein L3 | 0.0337667 |
| SMAD3 | SMAD family member 3 | 0.0333492 |
| TRIB2 | tribbles pseudokinase 2 | 0.0332 |
| NONO | non-POU domain containing, octamer-binding | 0.0307353 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0306775 |
| SET | SET nuclear proto-oncogene | 0.0297875 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0297309 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0286347 |
| AHNAK | AHNAK nucleoprotein | 0.0284462 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0277942 |
| AOPEP | aminopeptidase O (putative) | 0.0276281 |
| KLHL13 | kelch-like family member 13 | 0.0276256 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0275959 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0272576 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0266238 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0261809 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0261564 |
| FRMD4A | FERM domain containing 4A | 0.026093 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256248 |
| VEGFA | vascular endothelial growth factor A | 0.0252339 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0248939 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0242743 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0241567 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0240226 |
| PLEC | plectin | 0.0239721 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0237795 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0236018 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0232877 |
| TPM1 | tropomyosin 1 (alpha) | 0.0232144 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0230686 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0229677 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0229544 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0229126 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0226093 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0220414 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0217649 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0217164 |
| PDE10A | phosphodiesterase 10A | 0.0216698 |
| CYTH1 | cytohesin 1 | 0.0211862 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0208639 |
| DST | dystonin | 0.0205531 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0205038 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0203645 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0203353 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0203285 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0203092 |
| SON | SON DNA binding protein | 0.0202385 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0198339 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0196862 |
| RUNX1 | runt-related transcription factor 1 | 0.0195014 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0194998 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0192955 |
| GLI3 | GLI family zinc finger 3 | 0.0192153 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0191662 |
| TBX2 | T-box 2 | 0.0191094 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0190685 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0190213 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0189303 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0186172 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0185292 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0183648 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0183182 |
| RET | ret proto-oncogene | 0.0182803 |
| FOXO3 | forkhead box O3 | 0.0180876 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0178755 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0178718 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0178267 |
| NFIB | nuclear factor I/B | 0.0176888 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0175294 |
| TENM4 | teneurin transmembrane protein 4 | 0.0174683 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0171986 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0171961 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0171706 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0171121 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.0170843 |
| DLG5 | discs, large homolog 5 (Drosophila) | 0.0170268 |
| RLIM | ring finger protein, LIM domain interacting | 0.0168376 |
| TLE4 | transducin-like enhancer of split 4 | 0.0167596 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0167064 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0166423 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.016607 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0165925 |
| CCNY | cyclin Y | 0.0165319 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0165111 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.016408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.516021 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.269938 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.104245 |
| NRG1 | neuregulin 1 | -0.0904034 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0868043 |
| VIM | vimentin | -0.0619744 |
| COL1A1 | collagen, type I, alpha 1 | -0.0593985 |
| PTMA | prothymosin, alpha | -0.0569392 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0559513 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0488795 |
| GDF15 | growth differentiation factor 15 | -0.0486571 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0482278 |
| MEF2A | myocyte enhancer factor 2A | -0.0460475 |
| RPL34 | ribosomal protein L34 | -0.0427138 |
| RPL23 | ribosomal protein L23 | -0.0412512 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0395744 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390668 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0390133 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0382917 |
| GOLGA4 | golgin A4 | -0.0375015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0359657 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0353868 |
| NDRG1 | N-myc downstream regulated 1 | -0.0353814 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0343807 |
| STC1 | stanniocalcin 1 | -0.0341806 |
| RPS24 | ribosomal protein S24 | -0.0337177 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0333533 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0329402 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0325788 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0317014 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311113 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0308673 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0306174 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0301284 |
| GPC5 | glypican 5 | -0.0294823 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0292523 |
| IER3 | immediate early response 3 | -0.0286989 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0282449 |
| VDAC1 | voltage-dependent anion channel 1 | -0.02807 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0274457 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0273527 |
| RPL19 | ribosomal protein L19 | -0.027113 |
| COL3A1 | collagen, type III, alpha 1 | -0.0270483 |
| FNBP1 | formin binding protein 1 | -0.0268062 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0267718 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.026508 |
| S100A6 | S100 calcium binding protein A6 | -0.0263716 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0262709 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0250379 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0249309 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.024788 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.024155 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0238622 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0238317 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0232095 |
| ZNF292 | zinc finger protein 292 | -0.0230661 |
| S100A9 | S100 calcium binding protein A9 | -0.0224442 |
| GNAS | GNAS complex locus | -0.0224144 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.021784 |
| RPL35A | ribosomal protein L35a | -0.0213773 |
| RPL12 | ribosomal protein L12 | -0.0208639 |
| RPL38 | ribosomal protein L38 | -0.0205994 |
| CCNI | cyclin I | -0.020548 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0204749 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0204048 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0203823 |
| HMGA1 | high mobility group AT-hook 1 | -0.0201014 |
| TMSB10 | thymosin beta 10 | -0.0200705 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0199634 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0197939 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0197518 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0193761 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0191124 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0189956 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0188718 |
| RPS19 | ribosomal protein S19 | -0.018852 |
| DIAPH2 | diaphanous-related formin 2 | -0.0187138 |
| WDR45B | WD repeat domain 45B | -0.0186698 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0186514 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0186509 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.018497 |
| FAM162A | family with sequence similarity 162, member A | -0.018371 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0182349 |
| RTN4 | reticulon 4 | -0.0179248 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0178539 |
| CALD1 | caldesmon 1 | -0.0175723 |
| RPL27 | ribosomal protein L27 | -0.0175146 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0173762 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0170216 |
| SRP54 | signal recognition particle 54kDa | -0.0169605 |
| FTL | ferritin, light polypeptide | -0.0169371 |
| RPS11 | ribosomal protein S11 | -0.0169135 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0168138 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0167863 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0166863 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0165681 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0163569 |
| RBM25 | RNA binding motif protein 25 | -0.0163425 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0162861 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0162512 |
