| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.255293 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.186075 |
| VEGFA | vascular endothelial growth factor A | 0.130063 |
| PLEC | plectin | 0.104838 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.103234 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.102732 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0910265 |
| CALR | calreticulin | 0.0730264 |
| ATP13A3 | ATPase type 13A3 | 0.0630019 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0610412 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0599152 |
| STC1 | stanniocalcin 1 | 0.057612 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0547406 |
| SMAD3 | SMAD family member 3 | 0.0514188 |
| MT1X | metallothionein 1X | 0.0496874 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.049595 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0481188 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0460278 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0436867 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0434793 |
| NAV2 | neuron navigator 2 | 0.0433181 |
| SPAG9 | sperm associated antigen 9 | 0.0428946 |
| RPL3 | ribosomal protein L3 | 0.0426546 |
| PTK2 | protein tyrosine kinase 2 | 0.0419712 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0419089 |
| ARRDC3 | arrestin domain containing 3 | 0.0418803 |
| APP | amyloid beta (A4) precursor protein | 0.0416219 |
| TMSB4X | thymosin beta 4, X-linked | 0.0411919 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0410874 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0408073 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0390467 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0380604 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0373611 |
| LDHA | lactate dehydrogenase A | 0.0371322 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0367605 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0366364 |
| RASA2 | RAS p21 protein activator 2 | 0.0365397 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.036428 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0363168 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0361474 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0359502 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0357835 |
| OGA | O-GlcNAcase | 0.0348585 |
| MYO9B | myosin IXB | 0.0335393 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0329634 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.032027 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0315011 |
| FMNL2 | formin-like 2 | 0.031237 |
| GOLGA4 | golgin A4 | 0.0310489 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0309547 |
| YBX1 | Y box binding protein 1 | 0.0304732 |
| DENND5A | DENN/MADD domain containing 5A | 0.0294161 |
| PTMA | prothymosin, alpha | 0.0285344 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0284041 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0282802 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0282198 |
| MRTFA | myocardin related transcription factor A | 0.0282035 |
| HLA-B | major histocompatibility complex, class I, B | 0.0278801 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0274602 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0273874 |
| RLF | rearranged L-myc fusion | 0.0272021 |
| MED15 | mediator complex subunit 15 | 0.026947 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0266347 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0265742 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264569 |
| SEPTIN9 | septin 9 | 0.0257979 |
| SEPTIN2 | septin 2 | 0.0255809 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0255569 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.025188 |
| CCNY | cyclin Y | 0.0250972 |
| MSN | moesin | 0.0250066 |
| RBM39 | RNA binding motif protein 39 | 0.0249212 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0248188 |
| SDC4 | syndecan 4 | 0.0246622 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0246055 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0243936 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0243177 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0242921 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0240704 |
| UBC | ubiquitin C | 0.0240495 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.023895 |
| MLF1 | myeloid leukemia factor 1 | 0.0233897 |
| COL1A2 | collagen, type I, alpha 2 | 0.0233505 |
| FLNA | filamin A, alpha | 0.023195 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.023084 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0228033 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0225567 |
| KIF1B | kinesin family member 1B | 0.0224472 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0223502 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0222854 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0219843 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0219714 |
| OPTN | optineurin | 0.0218331 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0218267 |
| TNS1 | tensin 1 | 0.0216852 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0216555 |
| ICAM1 | intercellular adhesion molecule 1 | 0.021555 |
| RND3 | Rho family GTPase 3 | 0.0215293 |
| CADM1 | cell adhesion molecule 1 | 0.0215215 |
| HLA-C | major histocompatibility complex, class I, C | 0.0214614 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.180199 |
| CDH13 | cadherin 13 | -0.129471 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.125637 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118575 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0972377 |
| NDRG1 | N-myc downstream regulated 1 | -0.0922676 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0850637 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0849962 |
| COL1A1 | collagen, type I, alpha 1 | -0.0842745 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0767738 |
| MT2A | metallothionein 2A | -0.0742044 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0679607 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0671277 |
| COL5A1 | collagen, type V, alpha 1 | -0.0583586 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0557445 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0553968 |
| VCAN | versican | -0.0508215 |
| EGFR | epidermal growth factor receptor | -0.0490335 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0460803 |
| FBN1 | fibrillin 1 | -0.0460485 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0460409 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0440322 |
| CNTN5 | contactin 5 | -0.0434718 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.043335 |
| GLIS3 | GLIS family zinc finger 3 | -0.0433067 |
| CALD1 | caldesmon 1 | -0.0431223 |
| LOX | lysyl oxidase | -0.0430195 |
| IER3 | immediate early response 3 | -0.0410045 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0394012 |
| PRELID2 | PRELI domain containing 2 | -0.0392347 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0389061 |
| DPYD | dihydropyrimidine dehydrogenase | -0.03815 |
| HMGA1 | high mobility group AT-hook 1 | -0.0378408 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0377616 |
| RUNX1 | runt-related transcription factor 1 | -0.037652 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0376214 |
| ASPH | aspartate beta-hydroxylase | -0.0374297 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0372732 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0365894 |
| HDAC9 | histone deacetylase 9 | -0.0355912 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.035562 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0327753 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321576 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0320723 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0317989 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0314364 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0313979 |
| VCL | vinculin | -0.0311364 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.031007 |
| MAP1B | microtubule-associated protein 1B | -0.0305982 |
| SLC38A2 | solute carrier family 38, member 2 | -0.029773 |
| PRSS23 | protease, serine, 23 | -0.0297619 |
| FRMD4A | FERM domain containing 4A | -0.0288182 |
| HMGA2 | high mobility group AT-hook 2 | -0.0287753 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0286852 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0286409 |
| NABP1 | nucleic acid binding protein 1 | -0.0284489 |
| EPHB1 | EPH receptor B1 | -0.0277648 |
| OXR1 | oxidation resistance 1 | -0.0268915 |
| NEK10 | NIMA-related kinase 10 | -0.0265961 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0263546 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0262976 |
| NAV1 | neuron navigator 1 | -0.0259265 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0253267 |
| DGKI | diacylglycerol kinase, iota | -0.0252715 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0252659 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0247596 |
| ENO1 | enolase 1, (alpha) | -0.0246383 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0245365 |
| NREP | neuronal regeneration related protein | -0.0244508 |
| PALLD | palladin, cytoskeletal associated protein | -0.0244133 |
| EGR1 | early growth response 1 | -0.0242621 |
| BNC2 | basonuclin 2 | -0.0232944 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0232822 |
| TENM3 | teneurin transmembrane protein 3 | -0.023154 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0226869 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.022615 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0222104 |
| FOXP1 | forkhead box P1 | -0.0221582 |
| PDE10A | phosphodiesterase 10A | -0.0215201 |
| DST | dystonin | -0.0214952 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0213928 |
| ATXN1 | ataxin 1 | -0.0213047 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0213018 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0213005 |
| EXOC4 | exocyst complex component 4 | -0.0208264 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0207032 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0206392 |
| PRR16 | proline rich 16 | -0.0204501 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0204476 |
| CUX1 | cut-like homeobox 1 | -0.0200852 |
| RAI14 | retinoic acid induced 14 | -0.0195896 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0195048 |
| CNKSR3 | CNKSR family member 3 | -0.0194317 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0192512 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0186314 |
| GOLGB1 | golgin B1 | -0.0185873 |
| TMEM263 | transmembrane protein 263 | -0.0185729 |
| INTS6 | integrator complex subunit 6 | -0.0183561 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0182854 |
