| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.107446 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.107211 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0744007 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0736964 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0724079 |
| RPL3 | ribosomal protein L3 | 0.0654801 |
| RPS12 | ribosomal protein S12 | 0.0611591 |
| VEGFA | vascular endothelial growth factor A | 0.0599912 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0588412 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0535563 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.053448 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0508129 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.050203 |
| ASPH | aspartate beta-hydroxylase | 0.0499102 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0482958 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0474288 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0463031 |
| KRT8 | keratin 8, type II | 0.0460886 |
| TNS1 | tensin 1 | 0.0441722 |
| RPL37A | ribosomal protein L37a | 0.0438798 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0426165 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0408185 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0400634 |
| RPL11 | ribosomal protein L11 | 0.0365038 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0354212 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0349185 |
| PLEC | plectin | 0.0349068 |
| NDRG1 | N-myc downstream regulated 1 | 0.0348752 |
| RPS6 | ribosomal protein S6 | 0.0346846 |
| SET | SET nuclear proto-oncogene | 0.0336982 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0331797 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0315395 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0311188 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0309036 |
| EFNA1 | ephrin-A1 | 0.0307325 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0305745 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0294444 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0294152 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.028999 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0282001 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0281952 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0279492 |
| TMSB10 | thymosin beta 10 | 0.0278785 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0277666 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.027625 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0274947 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0269087 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0267617 |
| RPS3 | ribosomal protein S3 | 0.0267427 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0262921 |
| B2M | beta-2-microglobulin | 0.0258893 |
| RPL37 | ribosomal protein L37 | 0.0255124 |
| PEG3 | paternally expressed 3 | 0.0254857 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0248532 |
| TF | transferrin | 0.0244847 |
| BRD4 | bromodomain containing 4 | 0.0244819 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0244801 |
| CCNY | cyclin Y | 0.0244796 |
| LDHA | lactate dehydrogenase A | 0.0244672 |
| RPL9 | ribosomal protein L9 | 0.0244499 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0244322 |
| NONO | non-POU domain containing, octamer-binding | 0.0242132 |
| FMNL2 | formin-like 2 | 0.0240354 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0236283 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0235106 |
| CEP250 | centrosomal protein 250kDa | 0.0232696 |
| INSIG2 | insulin induced gene 2 | 0.0231671 |
| AHSG | alpha-2-HS-glycoprotein | 0.0228363 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.022734 |
| RPL31 | ribosomal protein L31 | 0.022599 |
| RPS17 | ribosomal protein S17 | 0.0224567 |
| FAT1 | FAT atypical cadherin 1 | 0.0224035 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0223906 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0223116 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0222332 |
| GSE1 | Gse1 coiled-coil protein | 0.0217095 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0214462 |
| OPTN | optineurin | 0.0210991 |
| SFTPA2 | surfactant protein A2 | 0.0208842 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0208674 |
| INTS6 | integrator complex subunit 6 | 0.0206433 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0206033 |
| FOXN3 | forkhead box N3 | 0.0199323 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0198966 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0197834 |
| ENO1 | enolase 1, (alpha) | 0.0197208 |
| AFDN | afadin, adherens junction formation factor | 0.0195154 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0194698 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0194576 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0194339 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0193384 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0192498 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0192478 |
| JAG1 | jagged 1 | 0.0188946 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0187584 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.018753 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0186776 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0185547 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 0.0185417 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0183485 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.30907 |
| FN1 | fibronectin 1 | -0.268621 |
| APOB | apolipoprotein B | -0.225437 |
| IGF2 | insulin-like growth factor 2 | -0.154222 |
| EHBP1 | EH domain binding protein 1 | -0.128164 |
| GPC6 | glypican 6 | -0.119842 |
| C3 | complement component 3 | -0.117002 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109795 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.103253 |
| ITGAV | integrin, alpha V | -0.097527 |
| VCL | vinculin | -0.0974643 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0828945 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0816684 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0813632 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0811671 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0751142 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0712892 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0681737 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.062985 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0612854 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0594126 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0587921 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0585029 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0582708 |
| TRIM26 | tripartite motif containing 26 | -0.0577891 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0563176 |
| PTCHD4 | patched domain containing 4 | -0.0550742 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0532207 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0517058 |
| JMJD1C | jumonji domain containing 1C | -0.051056 |
| EGR1 | early growth response 1 | -0.0503737 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0495941 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0493037 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0492167 |
| TMEM123 | transmembrane protein 123 | -0.0466531 |
| GPC3 | glypican 3 | -0.043694 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0436887 |
| GK | glycerol kinase | -0.0425238 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0423491 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0412588 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0403013 |
| RUNX1 | runt-related transcription factor 1 | -0.0399009 |
| A2M | alpha-2-macroglobulin | -0.0389937 |
| GDF15 | growth differentiation factor 15 | -0.0386795 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0372576 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0367059 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0366444 |
| ZNF644 | zinc finger protein 644 | -0.036528 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.036387 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0360748 |
| FAM135A | family with sequence similarity 135, member A | -0.0360038 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0357434 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0346952 |
| MRTFA | myocardin related transcription factor A | -0.0346734 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0344698 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0344442 |
| DOK6 | docking protein 6 | -0.0342948 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0329948 |
| MYO1E | myosin IE | -0.0326221 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0325427 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0324204 |
| FRMD5 | FERM domain containing 5 | -0.0323823 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0321424 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0307133 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | -0.0300932 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0300753 |
| PLAC8 | placenta-specific 8 | -0.0300568 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0295389 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0294877 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0287972 |
| OSMR | oncostatin M receptor | -0.0284352 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0279205 |
| BCL2L1 | BCL2-like 1 | -0.0279037 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0278555 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0277333 |
| GLG1 | golgi glycoprotein 1 | -0.027715 |
| STK17A | serine/threonine kinase 17a | -0.0275181 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0274422 |
| GNAS | GNAS complex locus | -0.0270306 |
| DST | dystonin | -0.0270195 |
| BPTF | bromodomain PHD finger transcription factor | -0.0269204 |
| LYZ | lysozyme | -0.0262756 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0257394 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0254661 |
| RAI14 | retinoic acid induced 14 | -0.0251273 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | -0.0249166 |
| DENND4A | DENN/MADD domain containing 4A | -0.0245372 |
| FILIP1L | filamin A interacting protein 1-like | -0.0242806 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0241075 |
| IER3 | immediate early response 3 | -0.0240484 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0238557 |
| LOX | lysyl oxidase | -0.0236468 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0235134 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0235067 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0232667 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.023221 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0229674 |
| RNF213 | ring finger protein 213 | -0.0228743 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0227266 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0227117 |
