| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.127127 |
| KRT8 | keratin 8, type II | 0.122539 |
| VEGFA | vascular endothelial growth factor A | 0.110744 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0942659 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0938255 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.090672 |
| LMO7 | LIM domain 7 | 0.0878839 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.072893 |
| RPL3 | ribosomal protein L3 | 0.0689188 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0551258 |
| PLEC | plectin | 0.0474885 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0467984 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0439282 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0434888 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0424175 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0424109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0421068 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0419706 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0402884 |
| TNS4 | tensin 4 | 0.0383247 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0378578 |
| MINK1 | misshapen-like kinase 1 | 0.037681 |
| ABHD2 | abhydrolase domain containing 2 | 0.0363719 |
| DSPP | dentin sialophosphoprotein | 0.0352699 |
| KRT18 | keratin 18, type I | 0.035187 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345047 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0339362 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0323039 |
| ANXA11 | annexin A11 | 0.0317274 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0301044 |
| TMSB4X | thymosin beta 4, X-linked | 0.0295692 |
| PCBP2 | poly(rC) binding protein 2 | 0.027761 |
| NONO | non-POU domain containing, octamer-binding | 0.0276743 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0275729 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0269383 |
| TPM3 | tropomyosin 3 | 0.0264476 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0261431 |
| ITGA6 | integrin, alpha 6 | 0.0261246 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.025935 |
| SET | SET nuclear proto-oncogene | 0.0256391 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0250983 |
| NDRG1 | N-myc downstream regulated 1 | 0.0250443 |
| EPHA2 | EPH receptor A2 | 0.0245611 |
| MYO5B | myosin VB | 0.0245179 |
| MLEC | malectin | 0.0242889 |
| DNM2 | dynamin 2 | 0.0235209 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234892 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0234688 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0233587 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0233382 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0232766 |
| POTEF | POTE ankyrin domain family, member F | 0.0231679 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0230292 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0224732 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0221901 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0221755 |
| RNF145 | ring finger protein 145 | 0.0217112 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0216963 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0215911 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0215561 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0207775 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0207377 |
| TXNIP | thioredoxin interacting protein | 0.0202548 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0200319 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0198677 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0198603 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0195671 |
| MED13 | mediator complex subunit 13 | 0.0194995 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.019425 |
| BRD4 | bromodomain containing 4 | 0.0194198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.019319 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0191864 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0191486 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0189332 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0187855 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0187794 |
| PCM1 | pericentriolar material 1 | 0.0187343 |
| PNN | pinin, desmosome associated protein | 0.0186858 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0184712 |
| ITGB4 | integrin, beta 4 | 0.0184412 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0183965 |
| HYOU1 | hypoxia up-regulated 1 | 0.0183571 |
| CPNE1 | copine I | 0.0182262 |
| SNX9 | sorting nexin 9 | 0.0180884 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0179547 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0177004 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0173564 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0172935 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0170217 |
| MUC13 | mucin 13, cell surface associated | 0.0167409 |
| SLK | STE20-like kinase | 0.0167168 |
| GAK | cyclin G associated kinase | 0.0166387 |
| RBM33 | RNA binding motif protein 33 | 0.0165737 |
| YAP1 | Yes-associated protein 1 | 0.0165105 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0164963 |
| YTHDC1 | YTH domain containing 1 | 0.0164353 |
| SVIL | supervillin | 0.0163752 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0161647 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0160543 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.016046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.286984 |
| NPSR1 | neuropeptide S receptor 1 | -0.212415 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.197842 |
| PTMA | prothymosin, alpha | -0.139786 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.121196 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0924568 |
| ANXA2 | annexin A2 | -0.0888786 |
| TMSB10 | thymosin beta 10 | -0.0871524 |
| GPHN | gephyrin | -0.0829617 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0792675 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0732298 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0718277 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0716743 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0656717 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0596005 |
| RPS24 | ribosomal protein S24 | -0.0517044 |
| VCL | vinculin | -0.0516369 |
| RPL34 | ribosomal protein L34 | -0.0511496 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0504638 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0441421 |
| PRSS3 | protease, serine, 3 | -0.0394459 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0393387 |
| EPCAM | epithelial cell adhesion molecule | -0.0392538 |
| AGR2 | anterior gradient 2 | -0.0388106 |
| RPS8 | ribosomal protein S8 | -0.03753 |
| RPLP1 | ribosomal protein, large, P1 | -0.037207 |
| POF1B | premature ovarian failure, 1B | -0.0357725 |
| PCDHB16 | protocadherin beta 16 | -0.0352896 |
| GOLGA4 | golgin A4 | -0.0351959 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0351833 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0351827 |
| IER3 | immediate early response 3 | -0.0350449 |
| ONECUT3 | one cut homeobox 3 | -0.0350117 |
| EREG | epiregulin | -0.0345756 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.03364 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331402 |
| RPL35A | ribosomal protein L35a | -0.0327109 |
| RPL26 | ribosomal protein L26 | -0.0326654 |
| INSIG1 | insulin induced gene 1 | -0.0324965 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0320176 |
| AHNAK | AHNAK nucleoprotein | -0.0319042 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0317146 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0316186 |
| CADPS | Ca++-dependent secretion activator | -0.0309052 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0306421 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0305822 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0303412 |
| HMGB1 | high mobility group box 1 | -0.0298451 |
| NFIA | nuclear factor I/A | -0.0297248 |
| RPL12 | ribosomal protein L12 | -0.0296228 |
| CCND1 | cyclin D1 | -0.0294832 |
| SBF2 | SET binding factor 2 | -0.0291775 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0290847 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0286684 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0285684 |
| CD44 | CD44 molecule (Indian blood group) | -0.0283662 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0282467 |
| FHIT | fragile histidine triad | -0.028034 |
| HMGA1 | high mobility group AT-hook 1 | -0.0279708 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0278072 |
| GDF15 | growth differentiation factor 15 | -0.0277664 |
| RPLP2 | ribosomal protein, large, P2 | -0.0276087 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0274194 |
| CANX | calnexin | -0.0273806 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0272458 |
| ENO1 | enolase 1, (alpha) | -0.0270866 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0270208 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0268866 |
| GNAS | GNAS complex locus | -0.0264633 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0262204 |
| LDLR | low density lipoprotein receptor | -0.0260394 |
| ABLIM1 | actin binding LIM protein 1 | -0.026035 |
| RPS23 | ribosomal protein S23 | -0.0258539 |
| TRIM2 | tripartite motif containing 2 | -0.0256811 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0256538 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0255469 |
| S100A10 | S100 calcium binding protein A10 | -0.0252687 |
| PIGR | polymeric immunoglobulin receptor | -0.0252622 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0252434 |
| S100A6 | S100 calcium binding protein A6 | -0.025092 |
| RPL13A | ribosomal protein L13a | -0.0249483 |
| RPS6 | ribosomal protein S6 | -0.0249472 |
| TMEM135 | transmembrane protein 135 | -0.0249096 |
| LDHA | lactate dehydrogenase A | -0.0248664 |
| LAMA4 | laminin, alpha 4 | -0.0244862 |
| RRBP1 | ribosome binding protein 1 | -0.0244741 |
| ARF1 | ADP-ribosylation factor 1 | -0.0240122 |
| RPLP0 | ribosomal protein, large, P0 | -0.0239093 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0238771 |
| FTL | ferritin, light polypeptide | -0.02384 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0232614 |
| COG5 | component of oligomeric golgi complex 5 | -0.0230198 |
| MAP4 | microtubule-associated protein 4 | -0.0229581 |
| PGK1 | phosphoglycerate kinase 1 | -0.0229034 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0228126 |
| KIF5B | kinesin family member 5B | -0.0226791 |
| RPS27A | ribosomal protein S27a | -0.0225083 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0224938 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0224776 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0223447 |
