| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CAPRIN2 | caprin family member 2 | 0.0825787 |
| MT2A | metallothionein 2A | 0.0801409 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0701918 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0639039 |
| RPS12 | ribosomal protein S12 | 0.0637726 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0584598 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0573445 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.055185 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0531592 |
| DST | dystonin | 0.0512924 |
| SQSTM1 | sequestosome 1 | 0.0481483 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0473673 |
| RPL37A | ribosomal protein L37a | 0.0469787 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0465501 |
| SMAD3 | SMAD family member 3 | 0.0415993 |
| HSPA8 | heat shock 70kDa protein 8 | 0.041045 |
| NONO | non-POU domain containing, octamer-binding | 0.039612 |
| RPL31 | ribosomal protein L31 | 0.0392369 |
| RPL3 | ribosomal protein L3 | 0.0388975 |
| TXNRD1 | thioredoxin reductase 1 | 0.0378824 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0375959 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.037531 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0371931 |
| PLEC | plectin | 0.0363535 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0349703 |
| RPS3 | ribosomal protein S3 | 0.0348253 |
| RPL36 | ribosomal protein L36 | 0.0329342 |
| EZR | ezrin | 0.0319223 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0305103 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0304475 |
| RPS17 | ribosomal protein S17 | 0.0299277 |
| RPL26 | ribosomal protein L26 | 0.0298854 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0298689 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0297796 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.029472 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0292174 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0289821 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0285464 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0280105 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0277952 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0276713 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0272945 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0270655 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0265719 |
| ANKRD11 | ankyrin repeat domain 11 | 0.026473 |
| ACTN1 | actinin, alpha 1 | 0.0263741 |
| CMIP | c-Maf inducing protein | 0.0263597 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0260603 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0250329 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0249904 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0248399 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0248197 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0247351 |
| PYGB | phosphorylase, glycogen; brain | 0.0241443 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0232807 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0232424 |
| SET | SET nuclear proto-oncogene | 0.0231505 |
| MLPH | melanophilin | 0.0230179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0229724 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0227529 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225131 |
| CEP250 | centrosomal protein 250kDa | 0.0222957 |
| ANGPTL4 | angiopoietin-like 4 | 0.0222501 |
| RPS6 | ribosomal protein S6 | 0.0221844 |
| SON | SON DNA binding protein | 0.0219529 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0216931 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0216637 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0215452 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.021484 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0211238 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0211059 |
| MCL1 | myeloid cell leukemia 1 | 0.0207625 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.020628 |
| KRT8 | keratin 8, type II | 0.0204791 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0203865 |
| HPCAL1 | hippocalcin-like 1 | 0.0203215 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0202464 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0198582 |
| RLIM | ring finger protein, LIM domain interacting | 0.0196452 |
| PCNT | pericentrin | 0.0196217 |
| RACK1 | receptor for activated C kinase 1 | 0.0196053 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.019594 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0195359 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0193608 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0189866 |
| MINK1 | misshapen-like kinase 1 | 0.0188091 |
| MOK | MOK protein kinase | 0.0186706 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0185162 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0184382 |
| STX1A | syntaxin 1A (brain) | 0.01814 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0179661 |
| EMP1 | epithelial membrane protein 1 | 0.0179571 |
| KLC1 | kinesin light chain 1 | 0.01782 |
| AREG | amphiregulin | 0.017722 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0176308 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0175702 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0175532 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0175425 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0174665 |
| RPL23 | ribosomal protein L23 | 0.0173751 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.320274 |
| PTMA | prothymosin, alpha | -0.116858 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0991148 |
| VIM | vimentin | -0.0927304 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0814465 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0795243 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0792938 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0733429 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0730414 |
| TP63 | tumor protein p63 | -0.0670487 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0642479 |
| CD44 | CD44 molecule (Indian blood group) | -0.0558642 |
| EHBP1 | EH domain binding protein 1 | -0.0516483 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0478653 |
| CANX | calnexin | -0.0473474 |
| TXNIP | thioredoxin interacting protein | -0.0441 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0428589 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0427752 |
| TMEM123 | transmembrane protein 123 | -0.0411873 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0404292 |
| TMSB10 | thymosin beta 10 | -0.0398471 |
| EPHA4 | EPH receptor A4 | -0.0396308 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0373126 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0370703 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0363983 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0362992 |
| CFAP299 | cilia and flagella associated protein 299 | -0.035281 |
| WASF2 | WAS protein family, member 2 | -0.035147 |
| MAP4 | microtubule-associated protein 4 | -0.0343459 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0336751 |
| COL5A2 | collagen, type V, alpha 2 | -0.0331531 |
| RAB7A | RAB7A, member RAS oncogene family | -0.03221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0319362 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0314598 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0308167 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.030755 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0297764 |
| SRGN | serglycin | -0.029617 |
| GLG1 | golgi glycoprotein 1 | -0.0294331 |
| CADM2 | cell adhesion molecule 2 | -0.0281757 |
| EFNA5 | ephrin-A5 | -0.0278803 |
| FTL | ferritin, light polypeptide | -0.0277021 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0272454 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0272217 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.026428 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0260118 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0258162 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249129 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0248918 |
| GNAS | GNAS complex locus | -0.0246855 |
| GOLGA4 | golgin A4 | -0.0244862 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0244635 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0242201 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0240377 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0239482 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0232572 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0231078 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0231049 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0227833 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0227642 |
| RAI1 | retinoic acid induced 1 | -0.0226384 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0225211 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0223535 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0216188 |
| MYADM | myeloid-associated differentiation marker | -0.0215563 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0214513 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0214324 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0214295 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0212636 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0211997 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211672 |
| HMGA1 | high mobility group AT-hook 1 | -0.0205794 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0205246 |
| KLF6 | Kruppel-like factor 6 | -0.0203889 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0203654 |
| JMJD1C | jumonji domain containing 1C | -0.0200526 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0200036 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0199942 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0199825 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0195571 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0195079 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0194816 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0191551 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0190344 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0187951 |
| NF1 | neurofibromin 1 | -0.0185196 |
| RBM25 | RNA binding motif protein 25 | -0.0184711 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0184228 |
| TAPBP | TAP binding protein (tapasin) | -0.0182843 |
| NBEAL1 | neurobeachin-like 1 | -0.0181185 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0179235 |
| ZNF292 | zinc finger protein 292 | -0.0179109 |
| FNIP1 | folliculin interacting protein 1 | -0.0177978 |
| SRP54 | signal recognition particle 54kDa | -0.0177969 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0177094 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0176867 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0176664 |
| RIGI | RNA sensor RIG-I | -0.0174393 |
| MYOF | myoferlin | -0.0173931 |
| PLIN2 | perilipin 2 | -0.0173096 |
