| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.301664 |
| PLEC | plectin | 0.102317 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0973915 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0810754 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0704025 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0695296 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0623576 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0613882 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0556833 |
| AHNAK | AHNAK nucleoprotein | 0.0553541 |
| RNF213 | ring finger protein 213 | 0.0519136 |
| SMAD3 | SMAD family member 3 | 0.0500995 |
| INTS6 | integrator complex subunit 6 | 0.0497475 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0460636 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0434504 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0412476 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0412231 |
| GRAMD1B | GRAM domain containing 1B | 0.0399292 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0394913 |
| ASPH | aspartate beta-hydroxylase | 0.0380685 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0376689 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0375916 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0367802 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0366298 |
| LAMB3 | laminin, beta 3 | 0.0352642 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0335142 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0332848 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0322432 |
| SLTM | SAFB-like, transcription modulator | 0.0320393 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0317093 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0301399 |
| MYOF | myoferlin | 0.0300309 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.029916 |
| GRB10 | growth factor receptor-bound protein 10 | 0.029691 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0296281 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0293673 |
| KRT7 | keratin 7, type II | 0.0292861 |
| KRT8 | keratin 8, type II | 0.0286015 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0279962 |
| HYOU1 | hypoxia up-regulated 1 | 0.0278004 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0275432 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0273081 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0270906 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0268002 |
| TNS3 | tensin 3 | 0.0259014 |
| HDLBP | high density lipoprotein binding protein | 0.0254774 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0253316 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0252473 |
| RPL3 | ribosomal protein L3 | 0.0250642 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0250146 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0249108 |
| SVIL | supervillin | 0.0248887 |
| SCEL | sciellin | 0.0245332 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0242871 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0241341 |
| EFNA5 | ephrin-A5 | 0.024041 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0239163 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0236616 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0233103 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0226647 |
| SMYD3 | SET and MYND domain containing 3 | 0.0225802 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0225474 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0223406 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0222632 |
| KRT18 | keratin 18, type I | 0.0221527 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0218048 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0217507 |
| AEBP2 | AE binding protein 2 | 0.0216515 |
| CTBP2 | C-terminal binding protein 2 | 0.0214906 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0214114 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0213816 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0212996 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0212909 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0211296 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0210465 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0209641 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0198595 |
| RPS3 | ribosomal protein S3 | 0.0197924 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0195205 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.019508 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0195061 |
| FOXP1 | forkhead box P1 | 0.0194336 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0192356 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.018754 |
| STC1 | stanniocalcin 1 | 0.018728 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0187176 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0186354 |
| CMIP | c-Maf inducing protein | 0.0185876 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.018565 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0185457 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0184073 |
| SQSTM1 | sequestosome 1 | 0.0182659 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.018255 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.018226 |
| GOLGA3 | golgin A3 | 0.0182057 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0180256 |
| HOMER1 | homer scaffolding protein 1 | 0.0180205 |
| HLA-B | major histocompatibility complex, class I, B | 0.0179717 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0177768 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0176306 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.403021 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.347058 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.105795 |
| TXNRD1 | thioredoxin reductase 1 | -0.105229 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0925599 |
| FTL | ferritin, light polypeptide | -0.0605578 |
| JMJD1C | jumonji domain containing 1C | -0.0597047 |
| TMEM165 | transmembrane protein 165 | -0.0562975 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0525363 |
| ANKRD12 | ankyrin repeat domain 12 | -0.048275 |
| CCNL1 | cyclin L1 | -0.0465816 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0459777 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0441265 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0411228 |
| SPAG9 | sperm associated antigen 9 | -0.0403793 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0388896 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0387236 |
| MKI67 | marker of proliferation Ki-67 | -0.0382085 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0368061 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0367356 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0353718 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0353599 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0350988 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0349371 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0346104 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0344697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0342101 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0341014 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0339268 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0333307 |
| RTN4 | reticulon 4 | -0.0330227 |
| NGLY1 | N-glycanase 1 | -0.0326973 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0313232 |
| DTNA | dystrobrevin, alpha | -0.0312589 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0303912 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0299867 |
| PDE8A | phosphodiesterase 8A | -0.029582 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0291365 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0291052 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.028915 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0286185 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0274208 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0274077 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0270207 |
| TMSB10 | thymosin beta 10 | -0.0269075 |
| SETD5 | SET domain containing 5 | -0.0268872 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0265433 |
| USP53 | ubiquitin specific peptidase 53 | -0.0265223 |
| SUCO | SUN domain containing ossification factor | -0.0263217 |
| OSMR | oncostatin M receptor | -0.0261762 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0259623 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0257357 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0257255 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0257191 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0256302 |
| CDCP1 | CUB domain containing protein 1 | -0.0255815 |
| TPD52 | tumor protein D52 | -0.0254628 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0250723 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0249856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0248597 |
| ARRDC3 | arrestin domain containing 3 | -0.0247941 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0247544 |
| UBC | ubiquitin C | -0.0247253 |
| GPHN | gephyrin | -0.0245284 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0242852 |
| RAB1A | RAB1A, member RAS oncogene family | -0.024108 |
| SEC61G | Sec61 gamma subunit | -0.0234246 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0232595 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.022944 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0226103 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0225786 |
| RPS2 | ribosomal protein S2 | -0.0224114 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0223606 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.022285 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0222186 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0221207 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0220698 |
| CCDC186 | coiled-coil domain containing 186 | -0.0220532 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0218888 |
| GOLGA4 | golgin A4 | -0.0218657 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.021742 |
| H1-0 | H1.0 linker histone | -0.0216984 |
| TFG | TRK-fused gene | -0.0214257 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0213838 |
| WASF2 | WAS protein family, member 2 | -0.0213496 |
| ZNF292 | zinc finger protein 292 | -0.021344 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0213311 |
| PAPOLA | poly(A) polymerase alpha | -0.0212784 |
| PRRC2C | proline-rich coiled-coil 2C | -0.021144 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0210798 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | -0.0208882 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0208176 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0207942 |
| ATP11B | ATPase, class VI, type 11B | -0.02075 |
| CES1 | carboxylesterase 1 | -0.0207054 |
| FNIP1 | folliculin interacting protein 1 | -0.020694 |
| RUNX1 | runt-related transcription factor 1 | -0.0205045 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0201504 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0200379 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0198666 |
