| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the DTP3_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.111786 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0804519 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0731232 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0690645 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0640156 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0639369 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0626423 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0569729 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0541583 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0506575 |
| APP | amyloid beta (A4) precursor protein | 0.0502528 |
| TPM3 | tropomyosin 3 | 0.0493577 |
| FAM107B | family with sequence similarity 107, member B | 0.0490692 |
| FMNL2 | formin-like 2 | 0.0490296 |
| SMAD3 | SMAD family member 3 | 0.0481358 |
| DST | dystonin | 0.0463482 |
| CMIP | c-Maf inducing protein | 0.0459993 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0450847 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0449311 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0447973 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0442381 |
| RPL3 | ribosomal protein L3 | 0.0429812 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0428982 |
| RPS12 | ribosomal protein S12 | 0.0420705 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0415628 |
| NDRG1 | N-myc downstream regulated 1 | 0.0413254 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0403452 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0393915 |
| RPL37A | ribosomal protein L37a | 0.0385771 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038518 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.038047 |
| EGFR | epidermal growth factor receptor | 0.0373206 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0372688 |
| PLEC | plectin | 0.0372533 |
| ASPH | aspartate beta-hydroxylase | 0.0369673 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0368772 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0368296 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.036567 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0359117 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0356479 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.035647 |
| ACTN1 | actinin, alpha 1 | 0.0343089 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0335022 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0332066 |
| AHNAK | AHNAK nucleoprotein | 0.0328104 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0327473 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0321847 |
| MYOF | myoferlin | 0.0317853 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.031057 |
| RPL31 | ribosomal protein L31 | 0.0304988 |
| YBX3 | Y box binding protein 3 | 0.0301103 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0300465 |
| HLA-B | major histocompatibility complex, class I, B | 0.0299665 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0295872 |
| PFKP | phosphofructokinase, platelet | 0.0291969 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0288334 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0283674 |
| RPS3 | ribosomal protein S3 | 0.0279114 |
| SVIL | supervillin | 0.0264315 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0263631 |
| MSN | moesin | 0.0262106 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0260025 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0258136 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0256072 |
| FLNB | filamin B, beta | 0.0254363 |
| ATXN1 | ataxin 1 | 0.0252568 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.025188 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0247371 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0241714 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0239994 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0238755 |
| CTBP2 | C-terminal binding protein 2 | 0.0238649 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0238286 |
| SFTPA2 | surfactant protein A2 | 0.0237886 |
| CYTH1 | cytohesin 1 | 0.0236499 |
| ZFHX3 | zinc finger homeobox 3 | 0.0234795 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0234773 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0234271 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0234134 |
| FLNA | filamin A, alpha | 0.0230129 |
| KLC1 | kinesin light chain 1 | 0.0229531 |
| SQSTM1 | sequestosome 1 | 0.0228982 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0227673 |
| NRG1 | neuregulin 1 | 0.0227048 |
| HLA-A | major histocompatibility complex, class I, A | 0.0226523 |
| HYOU1 | hypoxia up-regulated 1 | 0.022488 |
| LDHA | lactate dehydrogenase A | 0.0222396 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0220993 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.022005 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0218817 |
| RPL37 | ribosomal protein L37 | 0.0217585 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0217465 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0216436 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0215551 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.021525 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0214032 |
| PCBP2 | poly(rC) binding protein 2 | 0.0213994 |
| RPS17 | ribosomal protein S17 | 0.0213144 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0210637 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0204769 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.401802 |
| FTL | ferritin, light polypeptide | -0.236001 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.146807 |
| TMSB10 | thymosin beta 10 | -0.125762 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.115239 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.111267 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0980773 |
| IGF2 | insulin-like growth factor 2 | -0.0648029 |
| RPS21 | ribosomal protein S21 | -0.0558259 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0527335 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0521934 |
| PFN1 | profilin 1 | -0.0469279 |
| FGB | fibrinogen beta chain | -0.0451871 |
| RPL19 | ribosomal protein L19 | -0.0405717 |
| RPL8 | ribosomal protein L8 | -0.0375353 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0361862 |
| S100A10 | S100 calcium binding protein A10 | -0.0359612 |
| S100A6 | S100 calcium binding protein A6 | -0.0355929 |
| IER3 | immediate early response 3 | -0.0351516 |
| GNAS | GNAS complex locus | -0.0349041 |
| PTMA | prothymosin, alpha | -0.0346834 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.033737 |
| RPS5 | ribosomal protein S5 | -0.0331963 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0314657 |
| S100A9 | S100 calcium binding protein A9 | -0.03105 |
| EGR1 | early growth response 1 | -0.0307015 |
| RHOA | ras homolog family member A | -0.0301014 |
| RPLP0 | ribosomal protein, large, P0 | -0.0297272 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293297 |
| SERF2 | small EDRK-rich factor 2 | -0.0288822 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0270235 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0269621 |
| HMGB1 | high mobility group box 1 | -0.0264538 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0257 |
| HMGA1 | high mobility group AT-hook 1 | -0.0254946 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.024693 |
| SRGN | serglycin | -0.0237682 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0237093 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0234877 |
| FGG | fibrinogen gamma chain | -0.0232269 |
| RPL34 | ribosomal protein L34 | -0.0228753 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0228593 |
| DENND4A | DENN/MADD domain containing 4A | -0.0223977 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0219906 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0217571 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0213634 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0213446 |
| RPS16 | ribosomal protein S16 | -0.0213354 |
| RPS25 | ribosomal protein S25 | -0.021224 |
| POTEF | POTE ankyrin domain family, member F | -0.0211251 |
| ASTN2 | astrotactin 2 | -0.0210198 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0209214 |
| ACTG1 | actin gamma 1 | -0.0205446 |
| ECT2 | epithelial cell transforming 2 | -0.0201239 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0198321 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0198125 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0196846 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0195985 |
| TUBB | tubulin, beta class I | -0.0195844 |
| RPS24 | ribosomal protein S24 | -0.0194162 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0193278 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0191889 |
| RPL23A | ribosomal protein L23a | -0.0188638 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0183491 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0183124 |
| TUBA1B | tubulin, alpha 1b | -0.0180872 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0177044 |
| MYL12B | myosin, light chain 12B, regulatory | -0.017632 |
| CENPF | centromere protein F, 350/400kDa | -0.0175547 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0172949 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.01714 |
| UBC | ubiquitin C | -0.0171081 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0169839 |
| RPS15 | ribosomal protein S15 | -0.0169 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.016886 |
| RPS20 | ribosomal protein S20 | -0.0168499 |
| TPX2 | TPX2, microtubule-associated | -0.0167244 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0166212 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0166 |
| RAB1A | RAB1A, member RAS oncogene family | -0.016597 |
| RBM25 | RNA binding motif protein 25 | -0.0164946 |
| CENPE | centromere protein E, 312kDa | -0.0163832 |
| RPS23 | ribosomal protein S23 | -0.0163056 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0162804 |
| RPL32 | ribosomal protein L32 | -0.0160719 |
| NOP58 | NOP58 ribonucleoprotein | -0.0159515 |
| TAGLN2 | transgelin 2 | -0.0158203 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0155933 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0155885 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0154964 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0154775 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0154701 |
| RPL28 | ribosomal protein L28 | -0.0153192 |
| RAN | RAN, member RAS oncogene family | -0.015237 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0152168 |
| USP15 | ubiquitin specific peptidase 15 | -0.015138 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0146949 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0146626 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0146117 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0146106 |
