| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.144632 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.098572 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0980539 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.08519 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0849523 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0814257 |
| KRT17 | keratin 17, type I | 0.0795467 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0766398 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0763295 |
| SRPK2 | SRSF protein kinase 2 | 0.0751966 |
| NDRG1 | N-myc downstream regulated 1 | 0.0751201 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0747931 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0733166 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0725958 |
| FAM13A | family with sequence similarity 13, member A | 0.070693 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0705312 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0701784 |
| SFTPA2 | surfactant protein A2 | 0.0699614 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0690447 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.066798 |
| COPA | coatomer protein complex, subunit alpha | 0.0638611 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.063114 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0629847 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0591433 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0564568 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.05602 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0557504 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0556619 |
| NPTN | neuroplastin | 0.0545867 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0544361 |
| MYOF | myoferlin | 0.0543403 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0537938 |
| PTGES2 | prostaglandin E synthase 2 | 0.0532673 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0530988 |
| RIGI | RNA sensor RIG-I | 0.0520444 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0506849 |
| FMNL2 | formin-like 2 | 0.0504566 |
| TOP1 | topoisomerase (DNA) I | 0.046618 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0460649 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0458479 |
| MYO5B | myosin VB | 0.0457417 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.045445 |
| MT2A | metallothionein 2A | 0.0448701 |
| SMAD3 | SMAD family member 3 | 0.0442784 |
| ZNF451 | zinc finger protein 451 | 0.0438309 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0423788 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0422758 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0421087 |
| SPAG9 | sperm associated antigen 9 | 0.0417379 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0410977 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0410247 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0394903 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0392913 |
| TPD52 | tumor protein D52 | 0.0392024 |
| RBM39 | RNA binding motif protein 39 | 0.038012 |
| SETD5 | SET domain containing 5 | 0.0376652 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0372942 |
| MXD1 | MAX dimerization protein 1 | 0.0370791 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0368253 |
| JAK2 | Janus kinase 2 | 0.0359345 |
| NAV2 | neuron navigator 2 | 0.0359287 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0359284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0356869 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0355655 |
| FLNB | filamin B, beta | 0.0354874 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0354706 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0354376 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0352492 |
| PCBP2 | poly(rC) binding protein 2 | 0.0352118 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0349714 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0349601 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0349064 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0348809 |
| WDR43 | WD repeat domain 43 | 0.0348794 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0347076 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0346031 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0342423 |
| PCM1 | pericentriolar material 1 | 0.0341503 |
| SON | SON DNA binding protein | 0.0338918 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.03364 |
| ENAH | enabled homolog (Drosophila) | 0.0335763 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0333705 |
| RAB10 | RAB10, member RAS oncogene family | 0.0332687 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0331232 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0331107 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330177 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0327712 |
| RNF24 | ring finger protein 24 | 0.0326207 |
| MYO10 | myosin X | 0.0324884 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.032239 |
| HMGA2 | high mobility group AT-hook 2 | 0.0320554 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0320234 |
| FRY | furry homolog (Drosophila) | 0.0319429 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0318781 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0318252 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0316709 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0315881 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0313906 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0306289 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0304977 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.192122 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.130041 |
| ATOSA | atos homolog A | -0.128016 |
| LAMC2 | laminin, gamma 2 | -0.114257 |
| LAMB3 | laminin, beta 3 | -0.109032 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0978271 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0910688 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0842127 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0795446 |
| OSMR | oncostatin M receptor | -0.0788228 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0782003 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0754062 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0753166 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0736939 |
| MUC16 | mucin 16, cell surface associated | -0.0729875 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0715895 |
| ABHD17C | abhydrolase domain containing 17C | -0.0695332 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0689582 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0674308 |
| RBM47 | RNA binding motif protein 47 | -0.0670309 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0663274 |
| S100A10 | S100 calcium binding protein A10 | -0.0631295 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0618855 |
| EFNA5 | ephrin-A5 | -0.0612186 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.061044 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0604671 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0592613 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0578478 |
| KYNU | kynureninase | -0.0573693 |
| TMSB10 | thymosin beta 10 | -0.054696 |
| MYO5C | myosin VC | -0.0532397 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0524717 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0518303 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0511919 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.049861 |
| PARD3 | par-3 family cell polarity regulator | -0.0497808 |
| ZNF217 | zinc finger protein 217 | -0.048941 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0467466 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0459535 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0458215 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0457873 |
| VCAN | versican | -0.0457153 |
| TXNIP | thioredoxin interacting protein | -0.0451066 |
| TXNRD1 | thioredoxin reductase 1 | -0.0433909 |
| MYO1E | myosin IE | -0.0432971 |
| FN1 | fibronectin 1 | -0.0428917 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0426991 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0426935 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0421898 |
| ERBIN | erbb2 interacting protein | -0.0418249 |
| ANXA2 | annexin A2 | -0.041761 |
| ACTG1 | actin gamma 1 | -0.0416499 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0416005 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0413203 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.041267 |
| AHNAK | AHNAK nucleoprotein | -0.041016 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0408642 |
| TPM4 | tropomyosin 4 | -0.0406853 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0404802 |
| JMJD1C | jumonji domain containing 1C | -0.0401935 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0398557 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0390347 |
| AK1 | adenylate kinase 1 | -0.0388248 |
| GNAS | GNAS complex locus | -0.0385514 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0384717 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0381389 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0379109 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0375753 |
| THRB | thyroid hormone receptor, beta | -0.0375371 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0373194 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0371972 |
| SVIL | supervillin | -0.0369029 |
| SLMAP | sarcolemma associated protein | -0.0367221 |
| CUX1 | cut-like homeobox 1 | -0.0366986 |
| TJP2 | tight junction protein 2 | -0.0363962 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0359781 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0357497 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0357092 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.035647 |
| SMYD3 | SET and MYND domain containing 3 | -0.0356436 |
| BCL2L1 | BCL2-like 1 | -0.0355827 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0354792 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0348953 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0348852 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.034829 |
| PRSS23 | protease, serine, 23 | -0.034753 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0345322 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0341874 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0341336 |
| RPS21 | ribosomal protein S21 | -0.0333712 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.0331856 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0330966 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0329903 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0327947 |
| DENND2C | DENN/MADD domain containing 2C | -0.0326355 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0323989 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0323375 |
| RAB31 | RAB31, member RAS oncogene family | -0.0322224 |
| TUSC3 | tumor suppressor candidate 3 | -0.0321811 |
| PBRM1 | polybromo 1 | -0.0319287 |
