| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the DTP3_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.123066 |
| DST | dystonin | 0.121466 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.115787 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.113438 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0992054 |
| ASPH | aspartate beta-hydroxylase | 0.0908513 |
| PDE10A | phosphodiesterase 10A | 0.0905015 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.072615 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0658981 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.064761 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0584104 |
| GRAMD1B | GRAM domain containing 1B | 0.057453 |
| CDH13 | cadherin 13 | 0.0558285 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0548763 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.053476 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0514692 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0512269 |
| KYNU | kynureninase | 0.0499822 |
| NONO | non-POU domain containing, octamer-binding | 0.0486594 |
| TBXT | T-box transcription factor T | 0.0485388 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0484869 |
| PDLIM5 | PDZ and LIM domain 5 | 0.048479 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0477971 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0462578 |
| RTN1 | reticulon 1 | 0.0460713 |
| HDAC4 | histone deacetylase 4 | 0.04503 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0449508 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0426201 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0423074 |
| RPL31 | ribosomal protein L31 | 0.0419556 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0402013 |
| RPL3 | ribosomal protein L3 | 0.0400785 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0397781 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0394321 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0393448 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.039007 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0379942 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0371739 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0365735 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0355943 |
| SMYD3 | SET and MYND domain containing 3 | 0.035523 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0346203 |
| RPL23 | ribosomal protein L23 | 0.0335329 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0332031 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0331573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0328319 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0326231 |
| AHNAK | AHNAK nucleoprotein | 0.0320518 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0319848 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.031969 |
| COL4A5 | collagen, type IV, alpha 5 | 0.031733 |
| RLIM | ring finger protein, LIM domain interacting | 0.0316111 |
| KIAA0825 | KIAA0825 | 0.0316084 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0312777 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.0304564 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0303072 |
| FLNA | filamin A, alpha | 0.0301447 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0300475 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0296647 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0295899 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0294333 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0291467 |
| COL5A2 | collagen, type V, alpha 2 | 0.0290726 |
| GDA | guanine deaminase | 0.0282689 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0280976 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0280923 |
| SMAD2 | SMAD family member 2 | 0.0278408 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0274294 |
| PLEC | plectin | 0.0273933 |
| PTEN | phosphatase and tensin homolog | 0.0272974 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0271469 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0261372 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0260166 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0259428 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0256324 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0254706 |
| ATXN1 | ataxin 1 | 0.0248612 |
| RPS12 | ribosomal protein S12 | 0.0248241 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0247228 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0246371 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0243052 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.024231 |
| PDE7B | phosphodiesterase 7B | 0.0240355 |
| PCBP3 | poly(rC) binding protein 3 | 0.0240208 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0237979 |
| RPS4X | ribosomal protein S4, X-linked | 0.0237403 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0234999 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0231827 |
| RPS17 | ribosomal protein S17 | 0.0230573 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0230329 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0229337 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0227252 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0226972 |
| INTS6 | integrator complex subunit 6 | 0.0225707 |
| EXOC4 | exocyst complex component 4 | 0.0224828 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0224397 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0223162 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0219842 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0219293 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0216858 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.288927 |
| FN1 | fibronectin 1 | -0.191451 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.154968 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.142905 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124505 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.111226 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0803181 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0735943 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0711646 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0692485 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0581214 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0565135 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0563865 |
| NBEAL1 | neurobeachin-like 1 | -0.0555801 |
| SPAG9 | sperm associated antigen 9 | -0.051448 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0511057 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0509392 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0499519 |
| GOLGA4 | golgin A4 | -0.049769 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0492142 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0488669 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0484745 |
| SRGN | serglycin | -0.0474639 |
| PTMA | prothymosin, alpha | -0.0468771 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0465367 |
| MCL1 | myeloid cell leukemia 1 | -0.0459077 |
| RGS2 | regulator of G-protein signaling 2 | -0.0459017 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0445809 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0441946 |
| RTN4 | reticulon 4 | -0.0425172 |
| UBC | ubiquitin C | -0.0424915 |
| RPS2 | ribosomal protein S2 | -0.0415147 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.040579 |
| NDRG1 | N-myc downstream regulated 1 | -0.0405619 |
| IL6 | interleukin 6 | -0.037155 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0362567 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0360467 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.036005 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0359428 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0358088 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0355139 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0346777 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0346584 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0345496 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0343803 |
| STC1 | stanniocalcin 1 | -0.0333889 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0317818 |
| FTL | ferritin, light polypeptide | -0.0317384 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0315785 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0308456 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0306721 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0300892 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0297428 |
| FAM13A | family with sequence similarity 13, member A | -0.0292233 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0292059 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0289115 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0284315 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0283651 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0279455 |
| SEC24A | SEC24 family member A | -0.0276225 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0275208 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.027337 |
| SBF2 | SET binding factor 2 | -0.0269587 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0267878 |
| CCDC88A | coiled-coil domain containing 88A | -0.0267792 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0267713 |
| GNAS | GNAS complex locus | -0.0265304 |
| RPL38 | ribosomal protein L38 | -0.0262167 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0261941 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0260944 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0260414 |
| SUCO | SUN domain containing ossification factor | -0.0260073 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0259462 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0258077 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0256446 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0255226 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0251428 |
| EGR1 | early growth response 1 | -0.0250684 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0250239 |
| CA12 | carbonic anhydrase XII | -0.0250209 |
| CEP350 | centrosomal protein 350kDa | -0.0249733 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0248123 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0248096 |
| CEP170 | centrosomal protein 170kDa | -0.0247387 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0240887 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0239377 |
| WDR45B | WD repeat domain 45B | -0.0239187 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0238908 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0237481 |
| ZNF292 | zinc finger protein 292 | -0.0237057 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0232782 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0229968 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0229744 |
| BMERB1 | bMERB domain containing 1 | -0.0229637 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0228651 |
| S100A6 | S100 calcium binding protein A6 | -0.0227654 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0226961 |
| RPL36A | ribosomal protein L36a | -0.0223884 |
| SEPTIN7 | septin 7 | -0.0223219 |
| S100A10 | S100 calcium binding protein A10 | -0.0222025 |
