| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.155632 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.090998 |
| PYGB | phosphorylase, glycogen; brain | 0.0886105 |
| FLNB | filamin B, beta | 0.085231 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0841057 |
| AHNAK | AHNAK nucleoprotein | 0.0820046 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0816728 |
| EGFR | epidermal growth factor receptor | 0.0772264 |
| TXNRD1 | thioredoxin reductase 1 | 0.0677435 |
| RPL3 | ribosomal protein L3 | 0.0653773 |
| GLI2 | GLI family zinc finger 2 | 0.0618234 |
| EZR | ezrin | 0.0608185 |
| SMYD3 | SET and MYND domain containing 3 | 0.0602635 |
| VCL | vinculin | 0.0602082 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0542951 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0507001 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0504547 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0480955 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0475064 |
| DUSP4 | dual specificity phosphatase 4 | 0.0464548 |
| HDAC9 | histone deacetylase 9 | 0.0456286 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0433153 |
| TMEM65 | transmembrane protein 65 | 0.0432495 |
| SQSTM1 | sequestosome 1 | 0.0418443 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0417888 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0412915 |
| PLXNA1 | plexin A1 | 0.0412113 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0406191 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0403623 |
| NBEA | neurobeachin | 0.0399243 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0395627 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0389194 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0377865 |
| LOXL3 | lysyl oxidase-like 3 | 0.0362403 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.036172 |
| PRELID2 | PRELI domain containing 2 | 0.0359134 |
| ATP9B | ATPase, class II, type 9B | 0.0350965 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0327751 |
| TRERF1 | transcriptional regulating factor 1 | 0.0327674 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.032458 |
| EFNA5 | ephrin-A5 | 0.0324449 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0319896 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0318808 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.031758 |
| TJP1 | tight junction protein 1 | 0.0311162 |
| AMOTL2 | angiomotin like 2 | 0.0308716 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.030562 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0301687 |
| ANK2 | ankyrin 2, neuronal | 0.0301552 |
| PDGFC | platelet derived growth factor C | 0.0299611 |
| NBAS | neuroblastoma amplified sequence | 0.0299466 |
| TBC1D22A | TBC1 domain family, member 22A | 0.029786 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0295461 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0294418 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0291816 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0289475 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.028667 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0284383 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0281433 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0281212 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0280835 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.02797 |
| PKM | pyruvate kinase, muscle | 0.0269336 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0266764 |
| PGK1 | phosphoglycerate kinase 1 | 0.0266758 |
| HDLBP | high density lipoprotein binding protein | 0.0263838 |
| RBM39 | RNA binding motif protein 39 | 0.0256044 |
| NONO | non-POU domain containing, octamer-binding | 0.0255303 |
| FOXP1 | forkhead box P1 | 0.0254283 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0254018 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0253389 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0252284 |
| APP | amyloid beta (A4) precursor protein | 0.0248941 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0248753 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0248253 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0248162 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0242219 |
| YEATS2 | YEATS domain containing 2 | 0.0241756 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0239517 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0238409 |
| RTN4 | reticulon 4 | 0.023807 |
| NCKAP1 | NCK-associated protein 1 | 0.0237631 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.023723 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0235054 |
| GSE1 | Gse1 coiled-coil protein | 0.0234504 |
| DIDO1 | death inducer-obliterator 1 | 0.0233628 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0233137 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0232797 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.023224 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.022827 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0226476 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.0224795 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0223529 |
| CEP250 | centrosomal protein 250kDa | 0.0223157 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0222016 |
| BMP2K | BMP2 inducible kinase | 0.0219197 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0218861 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0211636 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0210885 |
| ADAR | adenosine deaminase, RNA-specific | 0.02104 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.298707 |
| PTMA | prothymosin, alpha | -0.0839648 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0657912 |
| RPS6 | ribosomal protein S6 | -0.0640872 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0638606 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0546261 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0487371 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0482021 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0476063 |
| RPS8 | ribosomal protein S8 | -0.0451955 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0420974 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0376662 |
| BMP10 | bone morphogenetic protein 10 | -0.0358247 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0358037 |
| RPLP1 | ribosomal protein, large, P1 | -0.0326008 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0309065 |
| HMGA1 | high mobility group AT-hook 1 | -0.0301554 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0279974 |
| CCND1 | cyclin D1 | -0.0274359 |
| RPL34 | ribosomal protein L34 | -0.0272909 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0269726 |
| GNAS | GNAS complex locus | -0.0269297 |
| FTL | ferritin, light polypeptide | -0.0263564 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0256965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0254975 |
| RPL31 | ribosomal protein L31 | -0.0254373 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0253521 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0248047 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0244855 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0241992 |
| DIAPH3 | diaphanous-related formin 3 | -0.0239121 |
| RPS19 | ribosomal protein S19 | -0.0234144 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0227421 |
| RPL19 | ribosomal protein L19 | -0.022701 |
| RPL32 | ribosomal protein L32 | -0.0227 |
| RPL36 | ribosomal protein L36 | -0.0224965 |
| PFN1 | profilin 1 | -0.0223762 |
| MT2A | metallothionein 2A | -0.0220886 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0219988 |
| RPLP0 | ribosomal protein, large, P0 | -0.0218833 |
| RPLP2 | ribosomal protein, large, P2 | -0.0218533 |
| RPL8 | ribosomal protein L8 | -0.0217819 |
| RPL35A | ribosomal protein L35a | -0.0215536 |
| MKI67 | marker of proliferation Ki-67 | -0.0215043 |
| RPS3 | ribosomal protein S3 | -0.0212079 |
| CENPE | centromere protein E, 312kDa | -0.0208947 |
| RPS5 | ribosomal protein S5 | -0.0208795 |
| RPS2 | ribosomal protein S2 | -0.0205398 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0205285 |
| RPS23 | ribosomal protein S23 | -0.0202391 |
| POTEF | POTE ankyrin domain family, member F | -0.0202229 |
| RPS11 | ribosomal protein S11 | -0.0200595 |
| RPL28 | ribosomal protein L28 | -0.0183897 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0183894 |
| RPL12 | ribosomal protein L12 | -0.0183309 |
| QKI | QKI, KH domain containing, RNA binding | -0.018316 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0182596 |
| RPS16 | ribosomal protein S16 | -0.018213 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0180965 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0180782 |
| S100A9 | S100 calcium binding protein A9 | -0.0180152 |
| RPS25 | ribosomal protein S25 | -0.0179149 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0178936 |
| RPL9 | ribosomal protein L9 | -0.0177813 |
| ECT2 | epithelial cell transforming 2 | -0.0170176 |
| NOP58 | NOP58 ribonucleoprotein | -0.0166166 |
| HMGB1 | high mobility group box 1 | -0.0164513 |
| TMSB10 | thymosin beta 10 | -0.0164167 |
| CENPF | centromere protein F, 350/400kDa | -0.0164096 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0163134 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0162838 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0162738 |
| RPL37A | ribosomal protein L37a | -0.0156778 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0154215 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0151035 |
| SEPTIN7 | septin 7 | -0.0149727 |
| RPS27A | ribosomal protein S27a | -0.0149172 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0146982 |
| RPL26 | ribosomal protein L26 | -0.0146384 |
| PRDX2 | peroxiredoxin 2 | -0.0144817 |
| S100A10 | S100 calcium binding protein A10 | -0.0143681 |
| VIM | vimentin | -0.0142046 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0140713 |
| ZNF207 | zinc finger protein 207 | -0.0138985 |
| RPL5 | ribosomal protein L5 | -0.0138922 |
| RPS13 | ribosomal protein S13 | -0.0138842 |
| TUBB4B | tubulin, beta 4B class IVb | -0.013623 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.013578 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0134737 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0132463 |
| RPS14 | ribosomal protein S14 | -0.0131179 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.013018 |
| FAM162A | family with sequence similarity 162, member A | -0.0129638 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0128044 |
| RPS10 | ribosomal protein S10 | -0.0127903 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0127565 |
| RPS29 | ribosomal protein S29 | -0.0125311 |
| TUBA1B | tubulin, alpha 1b | -0.0123924 |
| HELZ | helicase with zinc finger | -0.0123291 |
| MEIS2 | Meis homeobox 2 | -0.0122107 |
