| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.203446 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.117474 |
| VEGFA | vascular endothelial growth factor A | 0.106138 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.103909 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0968856 |
| SMAD3 | SMAD family member 3 | 0.0814001 |
| NONO | non-POU domain containing, octamer-binding | 0.0807237 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0707586 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0682995 |
| HLA-B | major histocompatibility complex, class I, B | 0.0652364 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0613962 |
| CEP250 | centrosomal protein 250kDa | 0.0501855 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0480209 |
| MLPH | melanophilin | 0.0479681 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0479565 |
| FN1 | fibronectin 1 | 0.0458601 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0442115 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0438545 |
| SFTPA2 | surfactant protein A2 | 0.0427823 |
| FAM20C | family with sequence similarity 20, member C | 0.0422504 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0405011 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0404415 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0391187 |
| RPL3 | ribosomal protein L3 | 0.0389312 |
| FLNA | filamin A, alpha | 0.0386207 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0377443 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0366527 |
| HLA-C | major histocompatibility complex, class I, C | 0.0359655 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0355694 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.035448 |
| RPS12 | ribosomal protein S12 | 0.0347458 |
| NAV2 | neuron navigator 2 | 0.0328092 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0320993 |
| RPS4X | ribosomal protein S4, X-linked | 0.0318666 |
| RPL23 | ribosomal protein L23 | 0.0309542 |
| MT2A | metallothionein 2A | 0.0307843 |
| APP | amyloid beta (A4) precursor protein | 0.0305074 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0302297 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0297337 |
| B2M | beta-2-microglobulin | 0.0285611 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.02833 |
| RLIM | ring finger protein, LIM domain interacting | 0.0282244 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0281951 |
| ACTN1 | actinin, alpha 1 | 0.0276681 |
| MSN | moesin | 0.0273857 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0272467 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0264035 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0253285 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.024661 |
| PLEC | plectin | 0.0245781 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.024419 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0236121 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0232198 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0231362 |
| APOL2 | apolipoprotein L, 2 | 0.0228728 |
| CPNE1 | copine I | 0.0226788 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0226747 |
| MYO10 | myosin X | 0.0221503 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0220853 |
| FAT1 | FAT atypical cadherin 1 | 0.0216742 |
| YBX1 | Y box binding protein 1 | 0.0216136 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0212909 |
| HMGA2 | high mobility group AT-hook 2 | 0.0212175 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0211478 |
| AHR | aryl hydrocarbon receptor | 0.0210322 |
| SERINC1 | serine incorporator 1 | 0.0209774 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0208539 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0208132 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0207864 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0205695 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0204912 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0204407 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0202249 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.020124 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0198995 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0197099 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0196964 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0196843 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0193625 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0189788 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0186861 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0186297 |
| RPL37 | ribosomal protein L37 | 0.0185338 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0185251 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0184969 |
| DIDO1 | death inducer-obliterator 1 | 0.018479 |
| OGA | O-GlcNAcase | 0.0184332 |
| RPS3 | ribosomal protein S3 | 0.0183258 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0181421 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.018037 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0178632 |
| SON | SON DNA binding protein | 0.0177174 |
| PGK1 | phosphoglycerate kinase 1 | 0.0171382 |
| TMSB4X | thymosin beta 4, X-linked | 0.016907 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0168913 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0168365 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.016731 |
| KRT8 | keratin 8, type II | 0.0165975 |
| DENND5A | DENN/MADD domain containing 5A | 0.0165924 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0165227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.268031 |
| FRMD4A | FERM domain containing 4A | -0.135026 |
| PDE10A | phosphodiesterase 10A | -0.11059 |
| VIM | vimentin | -0.0902504 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.075296 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0736066 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0727075 |
| IER3 | immediate early response 3 | -0.0666352 |
| GOLGA4 | golgin A4 | -0.0617289 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0612891 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.059644 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0569535 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0560222 |
| FTL | ferritin, light polypeptide | -0.0549865 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0532778 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0519993 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0512023 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0510534 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0501996 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0486108 |
| PTMA | prothymosin, alpha | -0.0423336 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0420675 |
| VCL | vinculin | -0.0415421 |
| DIAPH2 | diaphanous-related formin 2 | -0.0414251 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0413424 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0408653 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0401834 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0401406 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0394844 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.039227 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0391704 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0384788 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0381333 |
| ZNF292 | zinc finger protein 292 | -0.0377949 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0371444 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.037086 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0369777 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0369731 |
| MAP4 | microtubule-associated protein 4 | -0.0369019 |
| ARFGEF3 | ARFGEF family member 3 | -0.0364071 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0362687 |
| LOX | lysyl oxidase | -0.0359508 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0351881 |
| GNAS | GNAS complex locus | -0.0348139 |
| MYOF | myoferlin | -0.0347758 |
| CTSD | cathepsin D | -0.0345153 |
| SEC24A | SEC24 family member A | -0.0343398 |
| CADM1 | cell adhesion molecule 1 | -0.0341505 |
| SPAG9 | sperm associated antigen 9 | -0.0338611 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0337356 |
| RPS2 | ribosomal protein S2 | -0.0331516 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0329543 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0311362 |
| CANX | calnexin | -0.0309503 |
| ADM | adrenomedullin | -0.0309496 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0309296 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0304452 |
| GPC6 | glypican 6 | -0.0304052 |
| TMEM263 | transmembrane protein 263 | -0.0301474 |
| UBC | ubiquitin C | -0.0296964 |
| CALD1 | caldesmon 1 | -0.0294517 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0294371 |
| RPS24 | ribosomal protein S24 | -0.0293321 |
| PLIN2 | perilipin 2 | -0.0289771 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.028913 |
| MKI67 | marker of proliferation Ki-67 | -0.0286456 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0278957 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0278924 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.027438 |
| TMSB10 | thymosin beta 10 | -0.0273128 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0267994 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0266053 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0265162 |
| RPLP2 | ribosomal protein, large, P2 | -0.0261522 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0261519 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0258983 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0257544 |
| RTN4 | reticulon 4 | -0.0255762 |
| FNIP1 | folliculin interacting protein 1 | -0.0255499 |
| HLA-E | major histocompatibility complex, class I, E | -0.0255446 |
| LRRC7 | leucine rich repeat containing 7 | -0.0253874 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0253621 |
| RAI14 | retinoic acid induced 14 | -0.025073 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0249314 |
| GOLGB1 | golgin B1 | -0.0248122 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0247809 |
| FBXO11 | F-box protein 11 | -0.0245226 |
| CDH13 | cadherin 13 | -0.0245074 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0244913 |
| PALLD | palladin, cytoskeletal associated protein | -0.0244829 |
| DST | dystonin | -0.0243889 |
| TAPBP | TAP binding protein (tapasin) | -0.0243547 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0243034 |
| CD109 | CD109 molecule | -0.0242803 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0241516 |
| WASF2 | WAS protein family, member 2 | -0.023797 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0236825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0236466 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0235924 |
| SBF2 | SET binding factor 2 | -0.0233912 |
