| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.319805 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.119568 |
| CDH13 | cadherin 13 | 0.105683 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0977536 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0833175 |
| NRXN3 | neurexin 3 | 0.0825236 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0815574 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0814264 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0789241 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0757927 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0755772 |
| COL5A1 | collagen, type V, alpha 1 | 0.0713741 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0692582 |
| NDRG1 | N-myc downstream regulated 1 | 0.0660941 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0588084 |
| ATP13A3 | ATPase type 13A3 | 0.0554367 |
| FAM20C | family with sequence similarity 20, member C | 0.0527169 |
| STC1 | stanniocalcin 1 | 0.0526476 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0525415 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0524268 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0521333 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0519233 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0518581 |
| MYO10 | myosin X | 0.0508928 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0497909 |
| MSN | moesin | 0.0493364 |
| VEGFA | vascular endothelial growth factor A | 0.0466695 |
| GRB10 | growth factor receptor-bound protein 10 | 0.046457 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0460318 |
| ANXA5 | annexin A5 | 0.0445408 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0440116 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0437169 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0436209 |
| COPA | coatomer protein complex, subunit alpha | 0.0431868 |
| AHNAK | AHNAK nucleoprotein | 0.0426618 |
| EGFR | epidermal growth factor receptor | 0.0425982 |
| PGK1 | phosphoglycerate kinase 1 | 0.0425935 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0424741 |
| CADM1 | cell adhesion molecule 1 | 0.0422849 |
| PLEC | plectin | 0.0421191 |
| IL6 | interleukin 6 | 0.0411023 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0402089 |
| KAZN | kazrin, periplakin interacting protein | 0.038811 |
| CALD1 | caldesmon 1 | 0.0383751 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0380133 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0379254 |
| TNS3 | tensin 3 | 0.0372606 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0370332 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0362745 |
| VEGFC | vascular endothelial growth factor C | 0.0359532 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0359016 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0357587 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0356947 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0353047 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0352664 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0343195 |
| SDC4 | syndecan 4 | 0.0342569 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.033736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0334393 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0332076 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0332033 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0330018 |
| HLA-B | major histocompatibility complex, class I, B | 0.0329727 |
| SMAD3 | SMAD family member 3 | 0.0317576 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0309678 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0308469 |
| MAP4 | microtubule-associated protein 4 | 0.0304033 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.030186 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0298187 |
| AUTS2 | autism susceptibility candidate 2 | 0.0295845 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0294533 |
| FNBP4 | formin binding protein 4 | 0.0293497 |
| APOL2 | apolipoprotein L, 2 | 0.0293099 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0292963 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0291334 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0288418 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0288318 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0284943 |
| SYNJ2 | synaptojanin 2 | 0.028439 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0283674 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.027989 |
| EXOC4 | exocyst complex component 4 | 0.0279271 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.027828 |
| RND3 | Rho family GTPase 3 | 0.0277004 |
| FAM13A | family with sequence similarity 13, member A | 0.0266927 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0265632 |
| ANO6 | anoctamin 6 | 0.0264662 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0264372 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0263951 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0261497 |
| VIM | vimentin | 0.0261449 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.026067 |
| WTAP | Wilms tumor 1 associated protein | 0.0253609 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0253531 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.025271 |
| SNX1 | sorting nexin 1 | 0.0252608 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.025203 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0251891 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0251678 |
| TPM1 | tropomyosin 1 (alpha) | 0.025095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.386056 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117552 |
| PTMA | prothymosin, alpha | -0.0754733 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.068043 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0612823 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.057072 |
| MT2A | metallothionein 2A | -0.0541763 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0509675 |
| COL1A1 | collagen, type I, alpha 1 | -0.0496295 |
| PKM | pyruvate kinase, muscle | -0.049467 |
| FTL | ferritin, light polypeptide | -0.0474907 |
| MYOF | myoferlin | -0.0434827 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0420064 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.041726 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0413915 |
| SEPTIN7 | septin 7 | -0.0398444 |
| CCNI | cyclin I | -0.0388741 |
| CANX | calnexin | -0.03859 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.037012 |
| FN1 | fibronectin 1 | -0.0369433 |
| MAP1B | microtubule-associated protein 1B | -0.0366592 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0363321 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0361136 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.03557 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034992 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0349513 |
| HMGB1 | high mobility group box 1 | -0.034923 |
| ANLN | anillin, actin binding protein | -0.0348269 |
| MEF2A | myocyte enhancer factor 2A | -0.0337442 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0335692 |
| COL1A2 | collagen, type I, alpha 2 | -0.0329718 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.031635 |
| PDE10A | phosphodiesterase 10A | -0.0315707 |
| ARF1 | ADP-ribosylation factor 1 | -0.0312151 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.030519 |
| HDLBP | high density lipoprotein binding protein | -0.0299209 |
| GOLGA4 | golgin A4 | -0.0292226 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0289947 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.028688 |
| XPO1 | exportin 1 | -0.0283048 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0273631 |
| TMEM263 | transmembrane protein 263 | -0.0271105 |
| ZNF292 | zinc finger protein 292 | -0.0271002 |
| TXNIP | thioredoxin interacting protein | -0.0264042 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0263653 |
| S100A10 | S100 calcium binding protein A10 | -0.0263463 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0258496 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0254218 |
| RPL11 | ribosomal protein L11 | -0.0253063 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0249826 |
| LOXL2 | lysyl oxidase-like 2 | -0.0249732 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0247182 |
| TMEM123 | transmembrane protein 123 | -0.0245294 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0244794 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0240778 |
| MT1X | metallothionein 1X | -0.0239347 |
| RPS2 | ribosomal protein S2 | -0.0234229 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0233716 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0231877 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0230981 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0230344 |
| TPX2 | TPX2, microtubule-associated | -0.0226719 |
| CCDC88A | coiled-coil domain containing 88A | -0.0226017 |
| GNAS | GNAS complex locus | -0.0225106 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0219034 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0218714 |
| ANXA2 | annexin A2 | -0.0215899 |
| NOP58 | NOP58 ribonucleoprotein | -0.0215069 |
| CDC25C | cell division cycle 25C | -0.0214535 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0214456 |
| RPL34 | ribosomal protein L34 | -0.021154 |
| H3-3B | H3.3 histone B | -0.0211331 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0210741 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0210395 |
| RNF24 | ring finger protein 24 | -0.0207378 |
| RPS5 | ribosomal protein S5 | -0.0207291 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.020431 |
| BSG | basigin (Ok blood group) | -0.0202956 |
| MYADM | myeloid-associated differentiation marker | -0.0200911 |
| MALT1 | MALT1 paracaspase | -0.0200769 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0199736 |
| RPS23 | ribosomal protein S23 | -0.0199596 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0198202 |
| RPL32 | ribosomal protein L32 | -0.0197937 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0196154 |
| LOX | lysyl oxidase | -0.0195702 |
| LDHA | lactate dehydrogenase A | -0.0195574 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0195085 |
| PHKB | phosphorylase kinase, beta | -0.0194687 |
| LMAN2 | lectin, mannose-binding 2 | -0.0193691 |
| NUP58 | nucleoporin 58 | -0.0193123 |
| ANKRD33B | ankyrin repeat domain 33B | -0.018985 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0189174 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0188719 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0187388 |
| SMYD3 | SET and MYND domain containing 3 | -0.018681 |
| CDC27 | cell division cycle 27 | -0.0185683 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0184157 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0183643 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0183548 |
