| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the DTP3_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0995921 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0949249 |
| CEP250 | centrosomal protein 250kDa | 0.0778028 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0766855 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.073274 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0634129 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0628175 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0604985 |
| SMAD3 | SMAD family member 3 | 0.0604491 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0603896 |
| DST | dystonin | 0.0602137 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0601798 |
| NONO | non-POU domain containing, octamer-binding | 0.0594096 |
| CPNE1 | copine I | 0.0591331 |
| SMYD3 | SET and MYND domain containing 3 | 0.0571949 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0549102 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.05342 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0533524 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0532936 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0496309 |
| SET | SET nuclear proto-oncogene | 0.049321 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0489146 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.047015 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0464127 |
| INTS6 | integrator complex subunit 6 | 0.0459649 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0458247 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0436798 |
| POTEF | POTE ankyrin domain family, member F | 0.0432027 |
| PKM | pyruvate kinase, muscle | 0.0418802 |
| MSN | moesin | 0.0413675 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0413671 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0412127 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0409093 |
| FLNA | filamin A, alpha | 0.040707 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.04069 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0404961 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.039334 |
| MED13L | mediator complex subunit 13-like | 0.0389268 |
| FMNL2 | formin-like 2 | 0.0384196 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0380928 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0374554 |
| ACTN1 | actinin, alpha 1 | 0.037335 |
| YBX3 | Y box binding protein 3 | 0.036581 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0365383 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364528 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0361083 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0358428 |
| NIBAN2 | niban apoptosis regulator 2 | 0.03582 |
| OGA | O-GlcNAcase | 0.0357184 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0356725 |
| RANBP2 | RAN binding protein 2 | 0.0354193 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.035201 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0349233 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0347951 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0343219 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.034301 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0340335 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0337806 |
| RPL3 | ribosomal protein L3 | 0.03346 |
| FUS | FUS RNA binding protein | 0.0333194 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0332302 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0329348 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0323271 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0320452 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0319871 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0315687 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0314265 |
| NDRG1 | N-myc downstream regulated 1 | 0.0311383 |
| SEPTIN9 | septin 9 | 0.0308968 |
| PRKCA | protein kinase C, alpha | 0.0307466 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0306948 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0305024 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0301277 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.02992 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0297948 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0296635 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0294493 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0294103 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0294017 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0293094 |
| LMO7 | LIM domain 7 | 0.0290336 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0287811 |
| ZNF638 | zinc finger protein 638 | 0.0285679 |
| SEPTIN2 | septin 2 | 0.0284488 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0282817 |
| VMP1 | vacuole membrane protein 1 | 0.0282229 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0282222 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0281491 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0281235 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.027828 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0277486 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0275121 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0274017 |
| FAM168A | family with sequence similarity 168, member A | 0.027331 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0271563 |
| CALR | calreticulin | 0.0268375 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0264821 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0262214 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0262115 |
| SIK3 | SIK family kinase 3 | 0.0258444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.397272 |
| VIM | vimentin | -0.0829545 |
| TMSB10 | thymosin beta 10 | -0.077911 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0641503 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0549536 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0484237 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0471882 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.047066 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0419389 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0378099 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0359457 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0354459 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0348194 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0348049 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0330178 |
| NALCN | sodium leak channel, non selective | -0.0316465 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0306292 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0303954 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0302994 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0298968 |
| GPC6 | glypican 6 | -0.0296891 |
| TPM4 | tropomyosin 4 | -0.0294054 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0293103 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.028966 |
| SEPTIN7 | septin 7 | -0.0287692 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0286886 |
| MAP1B | microtubule-associated protein 1B | -0.0284149 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0280305 |
| RPL34 | ribosomal protein L34 | -0.0277698 |
| S100A10 | S100 calcium binding protein A10 | -0.0277381 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.027579 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0275603 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.027106 |
| GLCCI1 | glucocorticoid induced 1 | -0.0269578 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0268931 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0267843 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0267811 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255618 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0253676 |
| NEMF | nuclear export mediator factor | -0.025213 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0250392 |
| TMEM123 | transmembrane protein 123 | -0.0248703 |
| UBB | ubiquitin B | -0.0246787 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0243456 |
| RPL12 | ribosomal protein L12 | -0.0243154 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0242608 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0241133 |
| EFNA5 | ephrin-A5 | -0.0237218 |
| ACTG1 | actin gamma 1 | -0.0231716 |
| IGF2 | insulin-like growth factor 2 | -0.0231053 |
| RIGI | RNA sensor RIG-I | -0.0230422 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0229218 |
| RPL30 | ribosomal protein L30 | -0.0227739 |
| TP53 | tumor protein p53 | -0.0227462 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0227074 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0226071 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0225963 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0223999 |
| ZNF721 | zinc finger protein 721 | -0.0222484 |
| ENOSF1 | enolase superfamily member 1 | -0.0222287 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0222256 |
| SLC35F3 | solute carrier family 35, member F3 | -0.022006 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0217074 |
| ZFR | zinc finger RNA binding protein | -0.0214991 |
| CCNI | cyclin I | -0.0214516 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0213804 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0207903 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0205943 |
| HMGB1 | high mobility group box 1 | -0.0203311 |
| MTDH | metadherin | -0.020312 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0201816 |
| LDLR | low density lipoprotein receptor | -0.0200204 |
| RAI14 | retinoic acid induced 14 | -0.0199867 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.019961 |
| PAPOLA | poly(A) polymerase alpha | -0.0197133 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0196781 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0196239 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0194993 |
| IER3 | immediate early response 3 | -0.019333 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.019325 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0192431 |
| OSMR | oncostatin M receptor | -0.0191651 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0191 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0190075 |
| FCHO2 | FCH domain only 2 | -0.0188264 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0188222 |
| TMEM263 | transmembrane protein 263 | -0.0187365 |
| HMGA2 | high mobility group AT-hook 2 | -0.0187182 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.018619 |
| ERBIN | erbb2 interacting protein | -0.0185389 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0185311 |
| RFX7 | regulatory factor X, 7 | -0.0181718 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0181603 |
| LDHA | lactate dehydrogenase A | -0.0181457 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0180836 |
| FAF2 | Fas associated factor family member 2 | -0.0179457 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.017912 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0177517 |
| ANKRD37 | ankyrin repeat domain 37 | -0.01769 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0174602 |