| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | DTP3 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the DTP3_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0709281 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0699643 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0699593 |
| SMAD3 | SMAD family member 3 | 0.0681399 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0619212 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0563668 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0555313 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.053887 |
| PELO | pelota homolog (Drosophila) | 0.0470139 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0459946 |
| SMOX | spermine oxidase | 0.0429963 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0421992 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0413 |
| AHR | aryl hydrocarbon receptor | 0.0408477 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0404347 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0404248 |
| FAT1 | FAT atypical cadherin 1 | 0.0373524 |
| RPS12 | ribosomal protein S12 | 0.0370096 |
| OGA | O-GlcNAcase | 0.0356704 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0342593 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0340628 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0337237 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.032841 |
| SQSTM1 | sequestosome 1 | 0.03264 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321436 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0319003 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0316118 |
| CAB39 | calcium binding protein 39 | 0.0313127 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0308772 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0302887 |
| TPR | translocated promoter region, nuclear basket protein | 0.0300795 |
| APP | amyloid beta (A4) precursor protein | 0.0299661 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.029668 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.029255 |
| RNF145 | ring finger protein 145 | 0.0287028 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.028657 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.028632 |
| ADD3 | adducin 3 (gamma) | 0.0285296 |
| NEK7 | NIMA-related kinase 7 | 0.0285177 |
| VEGFA | vascular endothelial growth factor A | 0.0284849 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0282971 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0275728 |
| MT2A | metallothionein 2A | 0.0269102 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0268425 |
| RUNX2 | runt-related transcription factor 2 | 0.02673 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0262753 |
| HELZ | helicase with zinc finger | 0.0259314 |
| RBM39 | RNA binding motif protein 39 | 0.0256534 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0252727 |
| RPL37A | ribosomal protein L37a | 0.0251242 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0250005 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0247232 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0246982 |
| ANKRD11 | ankyrin repeat domain 11 | 0.024537 |
| ETNK1 | ethanolamine kinase 1 | 0.0242715 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0241741 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0236534 |
| FNBP1 | formin binding protein 1 | 0.0233033 |
| DST | dystonin | 0.0232924 |
| RPL31 | ribosomal protein L31 | 0.0231857 |
| AFDN | afadin, adherens junction formation factor | 0.0230642 |
| RPS3 | ribosomal protein S3 | 0.0229482 |
| YBX3 | Y box binding protein 3 | 0.022782 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0227485 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0224732 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0224248 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0224159 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0224008 |
| RANBP2 | RAN binding protein 2 | 0.0223879 |
| PLEC | plectin | 0.0222364 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0217715 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0217575 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.021631 |
| FBXO32 | F-box protein 32 | 0.0216028 |
| RBM33 | RNA binding motif protein 33 | 0.021425 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0211922 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0211006 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0206566 |
| TPM3 | tropomyosin 3 | 0.020499 |
| CD109 | CD109 molecule | 0.0204953 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0202824 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0201778 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0197495 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0193889 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0193869 |
| CREBRF | CREB3 regulatory factor | 0.0192151 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0191245 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0189576 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0188384 |
| WAC | WW domain containing adaptor with coiled-coil | 0.018723 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0186563 |
| YTHDC1 | YTH domain containing 1 | 0.0186467 |
| NUP58 | nucleoporin 58 | 0.0185193 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0184486 |
| SEPTIN9 | septin 9 | 0.0182039 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0181404 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0181303 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0181181 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0181064 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0180736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.428962 |
| FN1 | fibronectin 1 | -0.268775 |
| NRG1 | neuregulin 1 | -0.188192 |
| PTMA | prothymosin, alpha | -0.133466 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0955656 |
| TMSB10 | thymosin beta 10 | -0.0953774 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.093914 |
| HMGA2 | high mobility group AT-hook 2 | -0.0896697 |
| S100A6 | S100 calcium binding protein A6 | -0.0876058 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.083596 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0806345 |
| FTL | ferritin, light polypeptide | -0.0658057 |
| VCL | vinculin | -0.0625916 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0608158 |
| PLIN2 | perilipin 2 | -0.0535333 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0532425 |
| S100A10 | S100 calcium binding protein A10 | -0.050692 |
| VIM | vimentin | -0.0493646 |
| HLA-B | major histocompatibility complex, class I, B | -0.0472458 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0469624 |
| MAP1B | microtubule-associated protein 1B | -0.0455861 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0443581 |
| SYT1 | synaptotagmin I | -0.0436057 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.042543 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0415164 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0406051 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0393762 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0382295 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0375445 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0371809 |
| S100A9 | S100 calcium binding protein A9 | -0.0366194 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0362923 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0350547 |
| PALLD | palladin, cytoskeletal associated protein | -0.0347024 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343969 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0342587 |
| ASPH | aspartate beta-hydroxylase | -0.0340671 |
| EGR1 | early growth response 1 | -0.0339119 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0333224 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0332055 |
| LMNA | lamin A/C | -0.0326664 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0324662 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0322505 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0317909 |
| RAI14 | retinoic acid induced 14 | -0.0316227 |
| ACTG1 | actin gamma 1 | -0.0307433 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0303785 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0299353 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0297967 |
| TMSB4X | thymosin beta 4, X-linked | -0.0293886 |
| CANX | calnexin | -0.0293733 |
| GNAS | GNAS complex locus | -0.0292637 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0292053 |
| TMEM165 | transmembrane protein 165 | -0.0291895 |
| RPS21 | ribosomal protein S21 | -0.0289853 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0287871 |
| CTSD | cathepsin D | -0.0287384 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.028367 |
| RASAL2 | RAS protein activator like 2 | -0.0280975 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.027054 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0266457 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.026536 |
| TENM4 | teneurin transmembrane protein 4 | -0.0264049 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0261964 |
| TMEM263 | transmembrane protein 263 | -0.025951 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0258035 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.025797 |
| IER3 | immediate early response 3 | -0.0257835 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025348 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.024735 |
| LOX | lysyl oxidase | -0.0246221 |
| TPM4 | tropomyosin 4 | -0.0244769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0241822 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0239309 |
| H1-0 | H1.0 linker histone | -0.0234714 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0233626 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.02295 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.022943 |
| MCL1 | myeloid cell leukemia 1 | -0.0227684 |
| ENO1 | enolase 1, (alpha) | -0.0226841 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0226385 |
| NDRG1 | N-myc downstream regulated 1 | -0.0216471 |
| OXR1 | oxidation resistance 1 | -0.0216169 |
| RPS24 | ribosomal protein S24 | -0.021414 |
| KRT81 | keratin 81, type II | -0.0211382 |
| POTEF | POTE ankyrin domain family, member F | -0.0204673 |
| PRKCA | protein kinase C, alpha | -0.0204554 |
| HMGA1 | high mobility group AT-hook 1 | -0.0201164 |
| GPC6 | glypican 6 | -0.0200361 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0200348 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.020005 |
| TGFA | transforming growth factor, alpha | -0.019803 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0196961 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0196068 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0192998 |
| PFN1 | profilin 1 | -0.0192644 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0189746 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0189739 |
| TUBA1B | tubulin, alpha 1b | -0.0188316 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0187964 |
