DYNLL1 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description dynein, light chain, LC8-type 1|Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8655)
External Link http://www.ncbi.nlm.nih.gov/gene/8655
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174 interacting proteins for hub protein DYNLL1 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ACTB actin, beta
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
AGGF1 angiogenic factor with G patch and FHA domains 1
ALDOA aldolase A, fructose-bisphosphate
AMBRA1 autophagy/beclin-1 regulator 1
AMOT angiomotin
ARHGAP4 Rho GTPase activating protein 4
ASF1B anti-silencing function 1B histone chaperone
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAS1 breast carcinoma amplified sequence 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMF Bcl2 modifying factor
C14ORF1 chromosome 14 open reading frame 1
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD5 CD5 molecule
CEP152 centrosomal protein 152kDa
CHD6 chromodomain helicase DNA binding protein 6
CISH cytokine inducible SH2-containing protein
CLIP2 CAP-GLY domain containing linker protein 2
COPS5 COP9 signalosome subunit 5
CREB3L2 cAMP responsive element binding protein 3-like 2
CS citrate synthase
CTTNBP2NL CTTNBP2 N-terminal like
DAZ1 deleted in azoospermia 1
DCAF7 DDB1 and CUL4 associated factor 7
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEFA1 defensin, alpha 1
DLG2 discs, large homolog 2 (Drosophila)
DLG3 discs, large homolog 3 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNM2 dynamin 2
DNM3 dynamin 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DYNLRB1 dynein, light chain, roadblock-type 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EML3 echinoderm microtubule associated protein like 3
EPB41 erythrocyte membrane protein band 4.1
FAM107B family with sequence similarity 107, member B
FAM172A family with sequence similarity 172, member A
FAM83D family with sequence similarity 83, member D
FBXO30 F-box protein 30
FBXO38 F-box protein 38
FYN FYN proto-oncogene, Src family tyrosine kinase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLCCI1 glucocorticoid induced 1
GLUD1 glutamate dehydrogenase 1
GLUL glutamate-ammonia ligase
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPHN gephyrin
GRB2 growth factor receptor-bound protein 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
HIP1R huntingtin interacting protein 1 related
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA8 heat shock 70kDa protein 8
IFFO2 intermediate filament family orphan 2
KANK1 KN motif and ankyrin repeat domains 1
KANK2 KN motif and ankyrin repeat domains 2
KDM1A lysine (K)-specific demethylase 1A
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
LDHA lactate dehydrogenase A
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MARK3 MAP/microtubule affinity-regulating kinase 3
MAST1 microtubule associated serine/threonine kinase 1
MAST2 microtubule associated serine/threonine kinase 2
MASTL microtubule associated serine/threonine kinase-like
MDH1 malate dehydrogenase 1, NAD (soluble)
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MOB4 MOB family member 4, phocein
MORC3 MORC family CW-type zinc finger 3
MPO myeloperoxidase
MTA1 metastasis associated 1
MTCL1 microtubule crosslinking factor 1
MTPAP mitochondrial poly(A) polymerase
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO10 myosin X
MYO5A myosin VA (heavy chain 12, myoxin)
NDE1 nudE neurodevelopment protein 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEK6 NIMA-related kinase 6
NEK9 NIMA-related kinase 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NRF1 nuclear respiratory factor 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PABPC1 poly(A) binding protein, cytoplasmic 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARD3 par-3 family cell polarity regulator
PAX6 paired box 6
PDCD10 programmed cell death 10
PFKM phosphofructokinase, muscle
PFKP phosphofructokinase, platelet
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIGR polymeric immunoglobulin receptor
PIP prolactin-induced protein
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
POLH polymerase (DNA directed), eta
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAB4A RAB4A, member RAS oncogene family
RBL1 retinoblastoma-like 1
RCOR1 REST corepressor 1
RCOR3 REST corepressor 3
RGS2 regulator of G-protein signaling 2
RHO rhodopsin
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHROOM1 shroom family member 1
SHROOM3 shroom family member 3
SKP1 S-phase kinase-associated protein 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOGA1 suppressor of glucose, autophagy associated 1
SPAG5 sperm associated antigen 5
STK25 serine/threonine kinase 25
STRIP1 striatin interacting protein 1
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
THAP8 THAP domain containing 8
TLK1 tousled-like kinase 1
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TP53BP1 tumor protein p53 binding protein 1
TRAF3IP3 TRAF3 interacting protein 3
TRIM24 tripartite motif containing 24
TRPS1 trichorhinophalangeal syndrome I
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA3C tubulin, alpha 3c
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TXNDC17 thioredoxin domain containing 17
UBE2K ubiquitin-conjugating enzyme E2K
VIM vimentin
WDR34 WD repeat domain 34
WDR60 WD repeat domain 60
ZHX1 zinc fingers and homeoboxes 1
ZMYM3 zinc finger, MYM-type 3
ZMYM4 zinc finger, MYM-type 4
ZMYND11 zinc finger, MYND-type containing 11
ZNF354A zinc finger protein 354A
ZNF609 zinc finger protein 609