DYPHYLLINE Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs. (Chemical Entities of Biological Interest Ontology, CHEBI_4728)
External Link https://dgidb.org/results?searchType=drug&searchTerms=DYPHYLLINE
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Genes

7 interacting proteins for the DYPHYLLINE drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
PDE7B phosphodiesterase 7B 2.52057
PDE7A phosphodiesterase 7A 2.16049
PDE4C phosphodiesterase 4C, cAMP-specific 0.66721
PDE4A phosphodiesterase 4A, cAMP-specific 0.521497
PDE4B phosphodiesterase 4B, cAMP-specific 0.371888
PDE4D phosphodiesterase 4D, cAMP-specific 0.32877
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.270061