DYRK1A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A|This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1859)
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Genes

451 genes differentially expressed following the DYRK1A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
AKR1D1 aldo-keto reductase family 1, member D1 2.55802
BST1 bone marrow stromal cell antigen 1 2.55802
HPD 4-hydroxyphenylpyruvate dioxygenase 2.55802
DRD1 dopamine receptor D1 2.55802
ZNF404 zinc finger protein 404 2.55802
C16ORF86 chromosome 16 open reading frame 86 2.55802
CDK20 cyclin-dependent kinase 20 2.55802
EBI3 Epstein-Barr virus induced 3 2.55802
ZNF273 zinc finger protein 273 2.55802
KLF1 Kruppel-like factor 1 (erythroid) 2.55802
SLA2 Src-like-adaptor 2 2.55802
C10ORF90 chromosome 10 open reading frame 90 2.55802
COL6A6 collagen, type VI, alpha 6 2.55802
NTSR1 neurotensin receptor 1 (high affinity) 2.55802
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.55802
ZNF214 zinc finger protein 214 2.55802
CD7 CD7 molecule 2.55802
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.55802
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.55802
DISP2 dispatched homolog 2 (Drosophila) 2.55802
CDNF cerebral dopamine neurotrophic factor 2.55802
SPHK1 sphingosine kinase 1 2.55802
PLCD4 phospholipase C, delta 4 2.55802
TENT5C terminal nucleotidyltransferase 5C 2.55802
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 2.55802
RIGI RNA sensor RIG-I 2.55802
C3ORF62 chromosome 3 open reading frame 62 2.55802
SPN sialophorin 2.55802
CA10 carbonic anhydrase X 2.5219
HCST hematopoietic cell signal transducer 2.48869
CA9 carbonic anhydrase IX 2.48869
NPHP3 nephronophthisis 3 (adolescent) 2.48869
ALK anaplastic lymphoma receptor tyrosine kinase 2.48869
RASL10A RAS-like, family 10, member A 2.48869
KCNRG potassium channel regulator 2.48869
NAPSA napsin A aspartic peptidase 2.48869
PCDHA1 protocadherin alpha 1 2.48869
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.48869
HLF hepatic leukemia factor 2.48869
PCDHA2 protocadherin alpha 2 2.48869
MPRIP myosin phosphatase Rho interacting protein 2.48869
ACTL10 actin-like 10 2.48869
FPR3 formyl peptide receptor 3 2.48869
RAET1G retinoic acid early transcript 1G 2.48869
YY2 YY2 transcription factor 2.48869
EGFL6 EGF-like-domain, multiple 6 2.48869
CRIP2 cysteine-rich protein 2 2.48869
SCARA5 scavenger receptor class A, member 5 2.48869
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.48869
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 2.48869
NRN1 neuritin 1 2.48869
ZNF852 zinc finger protein 852 2.48869
CEMP1 cementum protein 1 2.48869
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 2.48869
PCDHB1 protocadherin beta 1 2.48869
PCDHB8 protocadherin beta 8 2.48869
ASB12 ankyrin repeat and SOCS box containing 12 2.48869
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.48869
MYCT1 myc target 1 2.48869
SOX18 SRY (sex determining region Y)-box 18 2.48869
OSGIN1 oxidative stress induced growth inhibitor 1 2.48869
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 2.48869
MRPL53 mitochondrial ribosomal protein L53 2.48869
CXORF65 chromosome X open reading frame 65 2.48869
PROB1 proline-rich basic protein 1 2.48869
AADACL3 arylacetamide deacetylase-like 3 2.48869
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.48869
ATG9B autophagy related 9B 2.48869
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 2.48869
GYPB glycophorin B (MNS blood group) 2.48869
SSTR5 somatostatin receptor 5 2.48869
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.48869
GPR162 G protein-coupled receptor 162 2.48869
LRRC8A leucine rich repeat containing 8 family, member A 2.48869
HPCAL4 hippocalcin like 4 2.48869
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.48869
CD1D CD1d molecule 2.48869
PLIN4 perilipin 4 2.48869
CABP4 calcium binding protein 4 2.48869
TMEM176B transmembrane protein 176B 2.48869
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.48869
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.48869
COXFA4L3 cytochrome c oxidase associated subunit FA4L3 2.48869
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.48869
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 2.48869
PCDHGA9 protocadherin gamma subfamily A, 9 2.48869
OR10H5 olfactory receptor, family 10, subfamily H, member 5 2.48869
ZAR1 zygote arrest 1 2.48869
MCHR1 melanin-concentrating hormone receptor 1 2.48869
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.48869
HBG2 hemoglobin, gamma G 2.48869
ALX4 ALX homeobox 4 2.48869
MGAT4D MGAT4 family, member D 2.48869
ACER1 alkaline ceramidase 1 2.48869
PLN phospholamban 2.48869
ACTA2 actin, alpha 2, smooth muscle, aorta 2.48869
STX11 syntaxin 11 2.48869
RTL8A retrotransposon Gag like 8A 2.48869
H3-5 H3.5 histone 2.48869
CIMIP7 ciliary microtubule inner protein 7 2.48869
TMT1B thiol methyltransferase 1B 2.48869
CFAP97D2 CFAP97 domain containing 2 2.48869
CTXND1 cortexin domain containing 1 2.48869
C20ORF204 chromosome 20 open reading frame 204 2.48869
H2BC26 H2B clustered histone 26 2.48869
GARIN4 golgi associated RAB2 interactor family member 4 2.48869
H4C13 H4 clustered histone 13 2.48869
CHCT1 CHD1 helical C-terminal domain containing 1 2.48869
LRATD1 LRAT domain containing 1 2.48869
SPACA9 sperm acrosome associated 9 2.48869
CCDC198 coiled-coil domain containing 198 2.48869
PLAAT4 phospholipase A and acyltransferase 4 2.48869
TMEM276-ZFTRAF1 TMEM276-ZFTRAF1 readthrough 2.48869
SPRR2D small proline-rich protein 2D 2.48869
SMLR1 small leucine-rich protein 1 2.48869
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.48869
C1QTNF2 C1q and tumor necrosis factor related protein 2 2.48869
CFAP43 cilia and flagella associated protein 43 2.48869
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.48869
MIA melanoma inhibitory activity 2.48869
GZMM granzyme M (lymphocyte met-ase 1) 2.48869
ZNF571 zinc finger protein 571 2.48869
ZIC1 Zic family member 1 2.48869
AMHR2 anti-Mullerian hormone receptor, type II 2.48869
PXDC1 PX domain containing 1 2.48869
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.48869
SCN10A sodium channel, voltage gated, type X alpha subunit 2.48869
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.48869
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 2.48869
ZBTB16 zinc finger and BTB domain containing 16 2.48869
PRR4 proline rich 4 (lacrimal) 2.48869
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.48869
LMNTD2 lamin tail domain containing 2 2.48869
USP49 ubiquitin specific peptidase 49 2.48869
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 2.48869
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.48869
NHLH1 nescient helix loop helix 1 2.48869
GC group-specific component (vitamin D binding protein) 2.48869
ACTL6B actin-like 6B 2.48869
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.48869
GATA3 GATA binding protein 3 2.48869
CNGA4 cyclic nucleotide gated channel alpha 4 2.48869
NPIPB7 nuclear pore complex interacting protein family, member B7 2.48869
FAM131C family with sequence similarity 131, member C 2.48869
VCX3B variable charge, X-linked 3B 2.48869
GTSF1 gametocyte specific factor 1 2.48869
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.48869
S100A2 S100 calcium binding protein A2 2.48869
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.48869
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.48869
LYG1 lysozyme G-like 1 2.48869
VNN2 vanin 2 2.48869
DPRX divergent-paired related homeobox 2.48869
ANKRD65 ankyrin repeat domain 65 2.48869
ANKRD63 ankyrin repeat domain 63 2.48869
LCN2 lipocalin 2 2.48869
TIGD3 tigger transposable element derived 3 2.48869
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.48869
TBC1D10C TBC1 domain family, member 10C 2.48869
GOLGA6A golgin A6 family, member A 2.48869
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.48869
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 2.48869
HKDC1 hexokinase domain containing 1 2.48869
RAD51AP2 RAD51 associated protein 2 2.48869
CST7 cystatin F (leukocystatin) 2.48869
TSPAN32 tetraspanin 32 2.48869
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.48869
ZMYND12 zinc finger, MYND-type containing 12 2.48869
TMEM150B transmembrane protein 150B 2.48869
SH2D1B SH2 domain containing 1B 2.48869
GNG8 guanine nucleotide binding protein (G protein), gamma 8 2.48869
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.48869
NGB neuroglobin 2.48869
FBXO39 F-box protein 39 2.48869
RSAD2 radical S-adenosyl methionine domain containing 2 2.48869
VILL villin-like 2.48869
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 2.48869
CH25H cholesterol 25-hydroxylase 2.48869
NOG noggin 2.48869
PSKH2 protein serine kinase H2 2.48869
EMP1 epithelial membrane protein 1 2.48869
DRD4 dopamine receptor D4 2.48869
CTSF cathepsin F 2.48869
SLC22A31 solute carrier family 22, member 31 2.48869
MOG myelin oligodendrocyte glycoprotein 2.48869
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 2.48869
RAB27B RAB27B, member RAS oncogene family 2.48869
MEIS2 Meis homeobox 2 2.48869
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.48869
CASQ2 calsequestrin 2 (cardiac muscle) 2.48869
HLA-DMB major histocompatibility complex, class II, DM beta 2.48869
LMX1A LIM homeobox transcription factor 1, alpha 2.48869
CXORF58 chromosome X open reading frame 58 2.48869
GOLGA8H golgin A8 family, member H 2.48869
LRRC24 leucine rich repeat containing 24 2.48869
ART1 ADP-ribosyltransferase 1 2.48869
SIGLEC15 sialic acid binding Ig-like lectin 15 2.48869
SIGLEC11 sialic acid binding Ig-like lectin 11 2.48869
PCDHGA1 protocadherin gamma subfamily A, 1 2.48869
FOXE3 forkhead box E3 2.48869
TMEM134 transmembrane protein 134 2.48869
C17ORF99 chromosome 17 open reading frame 99 2.48869
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.48869
CHI3L2 chitinase 3-like 2 2.48869
COL17A1 collagen, type XVII, alpha 1 2.48869
ZCCHC12 zinc finger, CCHC domain containing 12 2.48869
PCDHA11 protocadherin alpha 11 2.48869
MAOB monoamine oxidase B 2.48869
CFAP61 cilia and flagella associated protein 61 2.48869
EPHA3 EPH receptor A3 2.48869
FCRLB Fc receptor-like B 2.48869
DMRT2 doublesex and mab-3 related transcription factor 2 2.48869
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.48869
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.48869
LHX1 LIM homeobox 1 2.48869
PANO1 proapoptotic nucleolar protein 1 2.48869
TWIST2 twist family bHLH transcription factor 2 2.48869
TPH1 tryptophan hydroxylase 1 2.48869
CD38 CD38 molecule 2.48869
IGFBP6 insulin-like growth factor binding protein 6 2.48869
IRX3 iroquois homeobox 3 2.48869
SGK2 serum/glucocorticoid regulated kinase 2 2.48869
VWC2L von Willebrand factor C domain containing protein 2-like 2.48869
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.48869
IFITM10 interferon induced transmembrane protein 10 2.48869
TAS2R46 taste receptor, type 2, member 46 2.48869
DNAH2 dynein, axonemal, heavy chain 2 2.48869
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.48869
STEAP4 STEAP family member 4 2.48869
BFSP2 beaded filament structural protein 2, phakinin 2.48869
MPL MPL proto-oncogene, thrombopoietin receptor 2.48869
LGALS4 lectin, galactoside-binding, soluble, 4 2.48869
LGALS2 lectin, galactoside-binding, soluble, 2 2.48869
PGBD4 piggyBac transposable element derived 4 2.48869
KISS1R KISS1 receptor 2.48869
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.48869
KLLN killin, p53-regulated DNA replication inhibitor 2.48869
ETV2 ets variant 2 2.48869
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.48869
SPACA5 sperm acrosome associated 5 2.48869
SPTB spectrin, beta, erythrocytic 2.48869
CASR calcium-sensing receptor 2.48869
THEM5 thioesterase superfamily member 5 2.48869
TMEM45B transmembrane protein 45B 2.48869
UBC ubiquitin C 2.48869
LDLRAD4 low density lipoprotein receptor class A domain containing 4 2.48869
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 2.48869
NELL1 NEL-like 1 (chicken) 2.48869
FRMPD2 FERM and PDZ domain containing 2 2.48869
PLGLB1 plasminogen-like B1 2.48869
TMEM86A transmembrane protein 86A 2.48869
CD8A CD8a molecule 2.48869
TCF21 transcription factor 21 2.48869
C11ORF96 chromosome 11 open reading frame 96 2.48869
GREM1 gremlin 1, DAN family BMP antagonist 2.48869
CORIN corin, serine peptidase 2.48529
UPK2 uroplakin 2 2.48529
RIOK2 RIO kinase 2 2.46889
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 2.44533
LYRM2 LYR motif containing 2 2.4255
ELOVL6 ELOVL fatty acid elongase 6 2.40817
TCF19 transcription factor 19 2.40201
DDB1 damage-specific DNA binding protein 1, 127kDa 2.40201
CFAP74 cilia and flagella associated protein 74 2.3939
CCR5AS CCR5 antisense RNA 2.38311
TNS3 tensin 3 2.35895
COL12A1 collagen, type XII, alpha 1 2.3576
THOC5 THO complex 5 2.33278
LRRC49 leucine rich repeat containing 49 2.26086
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.25312
CRYL1 crystallin, lambda 1 2.24635
WRN Werner syndrome, RecQ helicase-like 2.23206
TUBB2B tubulin, beta 2B class IIb 2.22244
ABI1 abl-interactor 1 2.21516
SLC30A3 solute carrier family 30 (zinc transporter), member 3 2.19967
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.1799
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 2.1716
HMG20B high mobility group 20B 2.15482
EIF2A eukaryotic translation initiation factor 2A, 65kDa 2.14558
NDC80 NDC80 kinetochore complex component 2.12914
PPP5C protein phosphatase 5, catalytic subunit 2.10917
TRDMT1 tRNA aspartic acid methyltransferase 1 2.10572
STAMBP STAM binding protein 2.0875
C12ORF75 chromosome 12 open reading frame 75 2.08474
PNMA3 paraneoplastic Ma antigen 3 2.06353
OCEL1 occludin/ELL domain containing 1 2.06353
KIAA0232 KIAA0232 2.06169
DHCR24 24-dehydrocholesterol reductase 2.04571
ATP13A1 ATPase type 13A1 2.04571
DHODH dihydroorotate dehydrogenase (quinone) 2.02777
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2.02659
CADPS Ca++-dependent secretion activator 2.02024
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.02024
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.01525
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 2.01297
HELZ helicase with zinc finger 2.01297
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.01236
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.01113
IMPACT impact RWD domain protein 2.00003

decreased expression

Symbol Name Standardized Value
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -2.55802
RBM34 RNA binding motif protein 34 -2.55802
ANGPT1 angiopoietin 1 -2.55802
ALOX5 arachidonate 5-lipoxygenase -2.55802
DYDC2 DPY30 domain containing 2 -2.55802
RPL35 ribosomal protein L35 -2.55802
GMPPB GDP-mannose pyrophosphorylase B -2.55802
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type -2.55802
DPYS dihydropyrimidinase -2.55802
WNT5B wingless-type MMTV integration site family, member 5B -2.55802
PLAAT5 phospholipase A and acyltransferase 5 -2.52671
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 -2.52671
KNOP1 lysine-rich nucleolar protein 1 -2.52377
SHISA7 shisa family member 7 -2.48869
TDRD6 tudor domain containing 6 -2.48869
ARSD arylsulfatase D -2.48869
LIN37 lin-37 DREAM MuvB core complex component -2.48869
RSPO2 R-spondin 2 -2.48869
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.48869
TTPA tocopherol (alpha) transfer protein -2.48869
FOXL2NB FOXL2 neighbor -2.48869
SLC35E3 solute carrier family 35, member E3 -2.48869
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 -2.48869
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -2.48869
HIGD1B HIG1 hypoxia inducible domain family, member 1B -2.48869
FBXL16 F-box and leucine-rich repeat protein 16 -2.48869
BEGAIN brain-enriched guanylate kinase-associated -2.48869
NOP9 NOP9 nucleolar protein -2.48869
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.48869
MYO10 myosin X -2.48869
DNAH6 dynein, axonemal, heavy chain 6 -2.48869
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) -2.48869
ADAM33 ADAM metallopeptidase domain 33 -2.48869
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -2.48869
AKAP5 A kinase (PRKA) anchor protein 5 -2.48869
LEKR1 leucine, glutamate and lysine rich 1 -2.48869
TMEM263 transmembrane protein 263 -2.48869
SDCBP2 syndecan binding protein (syntenin) 2 -2.48869
RPS2 ribosomal protein S2 -2.48869
TRIM34 tripartite motif containing 34 -2.48869
H3C1 H3 clustered histone 1 -2.48869
PLPPR5 phospholipid phosphatase related 5 -2.48869
CFAP100 cilia and flagella associated protein 100 -2.48869
DUSP29 dual specificity phosphatase 29 -2.48869
HSH2D hematopoietic SH2 domain containing -2.48869
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -2.48869
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) -2.48869
TMEM191C transmembrane protein 191C -2.48869
GLCE glucuronic acid epimerase -2.48869
MYBPC2 myosin binding protein C, fast type -2.48869
PLXDC1 plexin domain containing 1 -2.48869
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.48869
RENBP renin binding protein -2.48869
NCAN neurocan -2.48869
TM6SF2 transmembrane 6 superfamily member 2 -2.48869
RHOBTB2 Rho-related BTB domain containing 2 -2.48869
CLGN calmegin -2.48869
SHISAL2A shisa like 2A -2.48869
NTNG1 netrin G1 -2.48869
DCLK3 doublecortin-like kinase 3 -2.48869
TMEM169 transmembrane protein 169 -2.48869
ZNF546 zinc finger protein 546 -2.48869
MUC19 mucin 19, oligomeric -2.48869
CCDC73 coiled-coil domain containing 73 -2.48869
RRH retinal pigment epithelium-derived rhodopsin homolog -2.48869
C22ORF15 chromosome 22 open reading frame 15 -2.48869
ZNF813 zinc finger protein 813 -2.48869
OSCAR osteoclast associated, immunoglobulin-like receptor -2.48869
AMIGO2 adhesion molecule with Ig-like domain 2 -2.48869
MAMLD1 mastermind-like domain containing 1 -2.48869
GPR18 G protein-coupled receptor 18 -2.48869
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -2.48869
CRYBB1 crystallin, beta B1 -2.48869
CPQ carboxypeptidase Q -2.48869
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.48869
ABI3 ABI family, member 3 -2.48869
ASAH2B N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B -2.48869
MST1R macrophage stimulating 1 receptor -2.48869
SLC25A35 solute carrier family 25, member 35 -2.48869
SHBG sex hormone-binding globulin -2.48869
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.48869
AZIN2 antizyme inhibitor 2 -2.48869
C3ORF49 chromosome 3 open reading frame 49 -2.48869
TIGD1 tigger transposable element derived 1 -2.48869
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 -2.4841
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -2.4634
CTXN1 cortexin 1 -2.46243
PCYOX1L prenylcysteine oxidase 1 like -2.4361
NHLRC2 NHL repeat containing 2 -2.40552
ZNF689 zinc finger protein 689 -2.4036
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 -2.39062
KIAA0513 KIAA0513 -2.39062
PHYH phytanoyl-CoA 2-hydroxylase -2.34457
SAP30 Sin3A-associated protein, 30kDa -2.3371
HOOK1 hook microtubule-tethering protein 1 -2.33278
ORC3 origin recognition complex, subunit 3 -2.33278
RBM10 RNA binding motif protein 10 -2.31397
VARS1 valyl-tRNA synthetase 1 -2.30497
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -2.3032
CILP2 cartilage intermediate layer protein 2 -2.29334
SPTBN4 spectrin, beta, non-erythrocytic 4 -2.29334
IFITM2 interferon induced transmembrane protein 2 -2.28514
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -2.28062
WDTC1 WD and tetratricopeptide repeats 1 -2.24563
SIAH3 siah E3 ubiquitin protein ligase family member 3 -2.24563
PSD pleckstrin and Sec7 domain containing -2.24563
EXOSC1 exosome component 1 -2.24563
ADRA1A adrenoceptor alpha 1A -2.24563
PROK2 prokineticin 2 -2.24563
RIN3 Ras and Rab interactor 3 -2.24563
HBQ1 hemoglobin, theta 1 -2.24563
HRH3 histamine receptor H3 -2.24563
NLRP2 NLR family, pyrin domain containing 2 -2.24563
TMEM81 transmembrane protein 81 -2.24563
SCARB2 scavenger receptor class B, member 2 -2.22244
ETFRF1 electron transfer flavoprotein regulatory factor 1 -2.21981
NRF1 nuclear respiratory factor 1 -2.21209
CDIN1 CDAN1 interacting nuclease 1 -2.21085
QARS1 glutaminyl-tRNA synthetase 1 -2.20904
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a -2.20807
TRAPPC6B trafficking protein particle complex 6B -2.18295
TRAPPC6A trafficking protein particle complex 6A -2.16338
LAMA5 laminin, alpha 5 -2.16338
TUBB4B tubulin, beta 4B class IVb -2.15678
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) -2.15482
DENND2C DENN/MADD domain containing 2C -2.14526
JAK1 Janus kinase 1 -2.13525
USF2 upstream transcription factor 2, c-fos interacting -2.13465
GPRIN2 G protein regulated inducer of neurite outgrowth 2 -2.11773
TTC3 tetratricopeptide repeat domain 3 -2.1092
HBS1L HBS1-like translational GTPase -2.10145
ACBD4 acyl-CoA binding domain containing 4 -2.10041
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.10041
SPP1 secreted phosphoprotein 1 -2.07641
MAST2 microtubule associated serine/threonine kinase 2 -2.06353
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.06337
TADA3 transcriptional adaptor 3 -2.05771
HMGN4 high mobility group nucleosomal binding domain 4 -2.05396
RARS1 arginyl-tRNA synthetase 1 -2.05322
PTK2 protein tyrosine kinase 2 -2.04571
EFNA5 ephrin-A5 -2.03292
CHMP1A charged multivesicular body protein 1A -2.03292
TTC9 tetratricopeptide repeat domain 9 -2.02777
STARD9 StAR-related lipid transfer (START) domain containing 9 -2.02376
CYTH3 cytohesin 3 -2.01735
PNCK pregnancy up-regulated nonubiquitous CaM kinase -2.01099
IFFO1 intermediate filament family orphan 1 -2.01099
DENND6B DENN/MADD domain containing 6B -2.01099
EPSTI1 epithelial stromal interaction 1 (breast) -2.01099
CXCL6 chemokine (C-X-C motif) ligand 6 -2.00621
FBXO36 F-box protein 36 -2.00621
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -2.00621