| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A|This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1859) |
| External Link | https://ncbi.nlm.nih.gov/gene/1859 |
| Similar Terms | |
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499 genes differentially expressed following the DYRK1A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0123728 |
| SNX7 | sorting nexin 7 | 0.0115126 |
| PCP4 | Purkinje cell protein 4 | 0.0114417 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0112316 |
| CCND1 | cyclin D1 | 0.0105756 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00940205 |
| TXLNA | taxilin alpha | 0.00937518 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00917376 |
| SFN | stratifin | 0.00901081 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00884618 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00869613 |
| PITX3 | paired-like homeodomain 3 | 0.00855866 |
| GPSM2 | G-protein signaling modulator 2 | 0.00818312 |
| PENK | proenkephalin | 0.00810356 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00809889 |
| KRT5 | keratin 5, type II | 0.00795857 |
| EFNB2 | ephrin-B2 | 0.00786848 |
| DACH1 | dachshund family transcription factor 1 | 0.00757686 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00757608 |
| PLBD1 | phospholipase B domain containing 1 | 0.0075002 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00749829 |
| TSPYL5 | TSPY-like 5 | 0.00745489 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00742778 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00740343 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00727668 |
| ZNF318 | zinc finger protein 318 | 0.00724768 |
| LTF | lactotransferrin | 0.00720924 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00701615 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00692486 |
| NMU | neuromedin U | 0.00690423 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00690392 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00680718 |
| NELFB | negative elongation factor complex member B | 0.00666767 |
| ITGA8 | integrin, alpha 8 | 0.00662055 |
| TYMS | thymidylate synthetase | 0.00661039 |
| RNF167 | ring finger protein 167 | 0.00658463 |
| S100A2 | S100 calcium binding protein A2 | 0.00658025 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00642232 |
| AUTS2 | autism susceptibility candidate 2 | 0.00640445 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00639137 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00633056 |
| MMP7 | matrix metallopeptidase 7 | 0.00627742 |
| TRIM28 | tripartite motif containing 28 | 0.00627331 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0061716 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00607852 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00605908 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00602707 |
| EFHD2 | EF-hand domain family, member D2 | 0.00601799 |
| RANBP1 | RAN binding protein 1 | 0.00599466 |
| TYRP1 | tyrosinase-related protein 1 | 0.00598877 |
| ABHD2 | abhydrolase domain containing 2 | 0.0059283 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00589647 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00589008 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00585318 |
| ZNF652 | zinc finger protein 652 | 0.00585238 |
| LMNB1 | lamin B1 | 0.00583415 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00582655 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00581078 |
| ABHD17A | abhydrolase domain containing 17A | 0.00578287 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00576509 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00575586 |
| TUBA4A | tubulin, alpha 4a | 0.00574905 |
| NDRG3 | NDRG family member 3 | 0.00573325 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00571689 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00568941 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00568295 |
| S100A12 | S100 calcium binding protein A12 | 0.00567874 |
| MEIS2 | Meis homeobox 2 | 0.00566705 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00566588 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00564967 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.005641 |
| SLC2A4RG | SLC2A4 regulator | 0.00561612 |
| TSPAN12 | tetraspanin 12 | 0.00560657 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00559486 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00558337 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00555844 |
| SCG5 | secretogranin V | 0.00553275 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00552089 |
| ZNF91 | zinc finger protein 91 | 0.00551834 |
| LCN2 | lipocalin 2 | 0.00551096 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00550556 |
| H2AX | H2A.X variant histone | 0.00549482 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00549018 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00548134 |
| AAGAB | alpha- and gamma-adaptin binding protein | 0.00545715 |
| RNF43 | ring finger protein 43 | 0.00543299 |
| DGKZ | diacylglycerol kinase, zeta | 0.00542453 |
| CDC7 | cell division cycle 7 | 0.00542307 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00539393 |
| FBN2 | fibrillin 2 | 0.0053721 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00537206 |
| TSPO | translocator protein (18kDa) | 0.00536398 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00535772 |
| HAS2 | hyaluronan synthase 2 | 0.00534062 |
| DENND2B | DENN domain containing 2B | 0.00532739 |
| TSPAN5 | tetraspanin 5 | 0.00532109 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.0053104 |
| EPHA4 | EPH receptor A4 | 0.0053085 |
| LBR | lamin B receptor | 0.00529075 |
| FPR1 | formyl peptide receptor 1 | 0.00527192 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00523323 |
| H2AZ1 | H2A.Z variant histone 1 | 0.00521558 |
| PKP1 | plakophilin 1 | 0.00519172 |
| CAMP | cathelicidin antimicrobial peptide | 0.00517151 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.00515713 |
| CSK | c-src tyrosine kinase | 0.00514066 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00513221 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00512198 |
| STK38 | serine/threonine kinase 38 | 0.00511794 |
| DHFR | dihydrofolate reductase | 0.00509537 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00508844 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00507868 |
| FBXW2 | F-box and WD repeat domain containing 2 | 0.00506817 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0050395 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00503587 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00502974 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00502638 |
| CDK8 | cyclin-dependent kinase 8 | 0.00502132 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00501823 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0050162 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00501421 |
| HDAC1 | histone deacetylase 1 | 0.00501398 |
| FST | follistatin | 0.00500901 |
| FSTL1 | follistatin-like 1 | 0.00500387 |
| DEK | DEK proto-oncogene | 0.00499657 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.00499343 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.00497541 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00497366 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00497194 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00496691 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00496596 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00496419 |
| KIF20A | kinesin family member 20A | 0.00494921 |
| ATP11B | ATPase, class VI, type 11B | 0.00494228 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00493971 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00492325 |
| ZNF264 | zinc finger protein 264 | 0.00490258 |
| PLPP3 | phospholipid phosphatase 3 | 0.00489992 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00487558 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00487122 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00487065 |
| CD84 | CD84 molecule | 0.0048506 |
| KRT14 | keratin 14, type I | 0.0048418 |
| CA12 | carbonic anhydrase XII | 0.00483053 |
| PROM1 | prominin 1 | 0.00481918 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00481563 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.00480927 |
| NKX3-1 | NK3 homeobox 1 | 0.00479928 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | 0.00479189 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00478288 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00478149 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00476186 |
| HIRA | histone cell cycle regulator | 0.00475555 |
| LOXL1 | lysyl oxidase-like 1 | 0.0047503 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00473404 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00472528 |
| DSP | desmoplakin | 0.00472254 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0047203 |
| LMNB2 | lamin B2 | 0.00471047 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00470855 |
| RPA1 | replication protein A1, 70kDa | 0.00470438 |
| RGS4 | regulator of G-protein signaling 4 | 0.00470266 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00470059 |
| ATP13A3 | ATPase type 13A3 | 0.00469902 |
| CSTA | cystatin A (stefin A) | 0.00469215 |
| TRMT5 | tRNA methyltransferase 5 | 0.00469055 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00467436 |
| DGCR8 | DGCR8 microprocessor complex subunit | 0.00466238 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.00465096 |
| DENND4B | DENN/MADD domain containing 4B | 0.0046411 |
| PKM | pyruvate kinase, muscle | 0.00463408 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00462239 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00461035 |
| RORA | RAR-related orphan receptor A | 0.00459197 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00457881 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00457322 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00457299 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.0045723 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00456836 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | 0.00456632 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00456588 |
| HTRA1 | HtrA serine peptidase 1 | 0.00455703 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | 0.00455399 |
| EXPH5 | exophilin 5 | 0.00454722 |
| ZNF329 | zinc finger protein 329 | 0.00453625 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00453168 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00452011 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00451857 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | 0.00451687 |
| CEP55 | centrosomal protein 55kDa | 0.00450643 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00450182 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00450105 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.00449633 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00449278 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.00448478 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.00447977 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.00447252 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.00446766 |
| CTBP1 | C-terminal binding protein 1 | 0.00445453 |
| TRH | thyrotropin-releasing hormone | 0.0044478 |
| UFL1 | UFM1-specific ligase 1 | 0.00444269 |
| TIPRL | TOR signaling pathway regulator | 0.00443138 |
| ANXA6 | annexin A6 | 0.00442525 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00441599 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00441454 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00440877 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.004408 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.00440546 |
| RPIA | ribose 5-phosphate isomerase A | 0.00438687 |
| TGOLN2 | trans-golgi network protein 2 | 0.00437666 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00436629 |
| MAGED1 | melanoma antigen family D1 | 0.00436295 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00436228 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00436122 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00435288 |
| RAPSN | receptor-associated protein of the synapse | 0.00433631 |
| CCDC47 | coiled-coil domain containing 47 | 0.00433074 |
| PRR16 | proline rich 16 | 0.00433008 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.00432895 |
| ZNF580 | zinc finger protein 580 | 0.00432289 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 | 0.00430992 |
| BIN2 | bridging integrator 2 | 0.00430794 |
| INTS3 | integrator complex subunit 3 | 0.00430199 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 0.00429212 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00429179 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00428608 |
| CCNB2 | cyclin B2 | 0.00428006 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00427966 |
| S100A8 | S100 calcium binding protein A8 | 0.00427694 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 0.00427684 |
| TMEM147 | transmembrane protein 147 | 0.00427175 |
| CCNF | cyclin F | 0.00425933 |
| PTPA | protein phosphatase 2 phosphatase activator | 0.00424722 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00424443 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00424289 |
| KRT16 | keratin 16, type I | 0.00424015 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00423996 |
| KIF4A | kinesin family member 4A | 0.00423478 |
| APMAP | adipocyte plasma membrane associated protein | 0.00423457 |
| APOC1 | apolipoprotein C-I | 0.00423224 |
| BCHE | butyrylcholinesterase | 0.00421796 |
| TARP | TCR gamma alternate reading frame protein | 0.00421711 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.004213 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00420811 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00420412 |
| CEP70 | centrosomal protein 70kDa | 0.00419816 |
| TSPOAP1 | TSPO associated protein 1 | 0.00419533 |
| SIX2 | SIX homeobox 2 | 0.00419061 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 | 0.00418774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | -0.0126299 |
| ATF3 | activating transcription factor 3 | -0.0125102 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0117048 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0116529 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.0115703 |
| XIC | X chromosome inactivation center | -0.0112819 |
| C3 | complement component 3 | -0.011103 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0106063 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0105458 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00994514 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00981189 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00974301 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00971305 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00956655 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00950521 |
| CP | ceruloplasmin (ferroxidase) | -0.0094621 |
| H1-2 | H1.2 linker histone, cluster member | -0.00938561 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00937383 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00934734 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00929082 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00923576 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00911382 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00903113 |
| RGCC | regulator of cell cycle | -0.00890946 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00890641 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0088045 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00872228 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0085116 |
| KLF6 | Kruppel-like factor 6 | -0.00849261 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0084458 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00835233 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00832962 |
| CLIC5 | chloride intracellular channel 5 | -0.00828618 |
| KYNU | kynureninase | -0.00828353 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00827603 |
| APOD | apolipoprotein D | -0.00822465 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.0082021 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00815276 |
| FGB | fibrinogen beta chain | -0.00814469 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00812365 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00807504 |
| DCN | decorin | -0.00805841 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00793858 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00791409 |
| XPO7 | exportin 7 | -0.0078237 |
| MX1 | MX dynamin-like GTPase 1 | -0.00776488 |
| DEFB1 | defensin, beta 1 | -0.00775334 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00775323 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0077486 |
| TSPAN8 | tetraspanin 8 | -0.0077473 |
| AREG | amphiregulin | -0.00763194 |
| CTSC | cathepsin C | -0.00754754 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00752859 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00751107 |
| THBS2 | thrombospondin 2 | -0.00747902 |
| ADIRF | adipogenesis regulatory factor | -0.0074671 |
| TSPAN13 | tetraspanin 13 | -0.00744427 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00743476 |
| IFI44L | interferon-induced protein 44-like | -0.00741521 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00740057 |
| MCL1 | myeloid cell leukemia 1 | -0.00739638 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00739563 |
| L1CAM | L1 cell adhesion molecule | -0.00726437 |
| CLU | clusterin | -0.0072562 |
| CFH | complement factor H | -0.00725284 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00720347 |
| HOXC6 | homeobox C6 | -0.00716529 |
| PRNP | prion protein | -0.00714762 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00713648 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00708941 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00706684 |
| CLCA4 | chloride channel accessory 4 | -0.00706623 |
| EGR2 | early growth response 2 | -0.00702883 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00701166 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00699665 |
| DAXX | death-domain associated protein | -0.00697436 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00695967 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00693981 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00692654 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00690244 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00683979 |
| HSPA4 | heat shock 70kDa protein 4 | -0.00669742 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0066924 |
| TFRC | transferrin receptor | -0.00665312 |
| CCN2 | cellular communication network factor 2 | -0.006646 |
| EGR1 | early growth response 1 | -0.00664032 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00662884 |
| MATN2 | matrilin 2 | -0.00662133 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0066117 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00660747 |
| MIR22HG | MIR22 host gene | -0.00659984 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0065796 |
| TSPAN3 | tetraspanin 3 | -0.00656663 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00652851 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0065245 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00648395 |
| TAGLN2 | transgelin 2 | -0.00647523 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00646581 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.00645224 |
| MMP1 | matrix metallopeptidase 1 | -0.00642971 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00640361 |
| FA2H | fatty acid 2-hydroxylase | -0.00640226 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00638983 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00637445 |
| FOXO1 | forkhead box O1 | -0.00632941 |
| IL32 | interleukin 32 | -0.00632734 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.0062871 |
| LUM | lumican | -0.00627168 |
| CRYAB | crystallin, alpha B | -0.00626451 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00626009 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00625672 |
| RRAD | Ras-related associated with diabetes | -0.00625422 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00625018 |
| DUSP5 | dual specificity phosphatase 5 | -0.00624841 |
| NLGN4X | neuroligin 4, X-linked | -0.00623353 |
| GPR137B | G protein-coupled receptor 137B | -0.00622076 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00620828 |
| BEX4 | brain expressed, X-linked 4 | -0.0062074 |
| ITM2C | integral membrane protein 2C | -0.006201 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -0.00619114 |
| ANXA1 | annexin A1 | -0.00617964 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00617814 |
| ITGA6 | integrin, alpha 6 | -0.00617278 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00613977 |
| FHL2 | four and a half LIM domains 2 | -0.00613484 |
| ARL14 | ADP-ribosylation factor-like 14 | -0.0061281 |
| GLRX | glutaredoxin (thioltransferase) | -0.0061234 |
| E2F2 | E2F transcription factor 2 | -0.00611169 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00609819 |
| LXN | latexin | -0.00609528 |
| GPX3 | glutathione peroxidase 3 | -0.00608697 |
| PLAT | plasminogen activator, tissue | -0.00608383 |
| TRAM1 | translocation associated membrane protein 1 | -0.00606388 |
| GSN | gelsolin | -0.00606363 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00605499 |
| OLFM1 | olfactomedin 1 | -0.00601967 |
| ASPN | asporin | -0.00601682 |
| MXRA5 | matrix-remodelling associated 5 | -0.00601055 |
| EPCAM | epithelial cell adhesion molecule | -0.00600999 |
| KRT20 | keratin 20, type I | -0.0060024 |
| C1S | complement component 1, s subcomponent | -0.00599154 |
| BTG3 | BTG family, member 3 | -0.00598958 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00595795 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00595446 |
| HSBP1 | heat shock factor binding protein 1 | -0.00594622 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00594456 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00592719 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00591732 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00590546 |
| EMC2 | ER membrane protein complex subunit 2 | -0.00588795 |
| PALLD | palladin, cytoskeletal associated protein | -0.00587695 |
| RAB1A | RAB1A, member RAS oncogene family | -0.00586924 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00586768 |
| C7 | complement component 7 | -0.00583486 |
| MVP | major vault protein | -0.00583379 |
| ABHD4 | abhydrolase domain containing 4 | -0.00582655 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00581424 |
| DST | dystonin | -0.00580275 |
| STOM | stomatin | -0.00579225 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00578822 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00573801 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0057211 |
| ASPH | aspartate beta-hydroxylase | -0.00571133 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00570965 |
| TSPAN1 | tetraspanin 1 | -0.00567979 |
| CD93 | CD93 molecule | -0.00566942 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00566756 |
| UPK1B | uroplakin 1B | -0.0056659 |
| DENND1B | DENN/MADD domain containing 1B | -0.00565423 |
| RGS5 | regulator of G-protein signaling 5 | -0.00565283 |
| LHFP | lipoma HMGIC fusion partner | -0.00564354 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00563815 |
| DCTN6 | dynactin 6 | -0.00562628 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00561645 |
| IL1R1 | interleukin 1 receptor, type I | -0.00561394 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00560166 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00559764 |
| CADM1 | cell adhesion molecule 1 | -0.00559027 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00558724 |
| TCF4 | transcription factor 4 | -0.0055778 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00556004 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00555556 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00553225 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00552663 |
| CORO1C | coronin, actin binding protein, 1C | -0.00552416 |
| RPS27L | ribosomal protein S27-like | -0.00552074 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00552067 |
| FMOD | fibromodulin | -0.005499 |
| TRIM22 | tripartite motif containing 22 | -0.00544525 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00542979 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00541021 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00540637 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00540539 |
| HNMT | histamine N-methyltransferase | -0.00540156 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00539108 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00538846 |
| FGA | fibrinogen alpha chain | -0.00538554 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0053616 |
| CFI | complement factor I | -0.00534727 |
| MGLL | monoglyceride lipase | -0.00534486 |
| FGG | fibrinogen gamma chain | -0.00534381 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0053077 |
| MFAP5 | microfibrillar associated protein 5 | -0.00530077 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00529047 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00528962 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00528775 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00528666 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00527535 |
| EMP1 | epithelial membrane protein 1 | -0.00527286 |
| ETNK1 | ethanolamine kinase 1 | -0.00526343 |
| WDR26 | WD repeat domain 26 | -0.00526275 |
| A2M | alpha-2-macroglobulin | -0.00526105 |
| MYO1B | myosin IB | -0.00524886 |
| RBM5 | RNA binding motif protein 5 | -0.00524801 |
| ZNF706 | zinc finger protein 706 | -0.00523277 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00522184 |
| CTTN | cortactin | -0.00520806 |
| BTG2 | BTG family, member 2 | -0.00520418 |
| AIM2 | absent in melanoma 2 | -0.00519718 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.00518393 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00518289 |
| AHNAK | AHNAK nucleoprotein | -0.00516955 |
| EFNA1 | ephrin-A1 | -0.00516043 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00513964 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00513713 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00513675 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00513484 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.0051276 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) | -0.00511768 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00511766 |
| TNNC1 | troponin C type 1 (slow) | -0.00511734 |
| CALCRL | calcitonin receptor-like | -0.00511556 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | -0.00511029 |
| KRT81 | keratin 81, type II | -0.00510798 |
| GMFB | glia maturation factor, beta | -0.0051046 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00510102 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0050996 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0050978 |
| CLDN1 | claudin 1 | -0.00508591 |
| THBD | thrombomodulin | -0.00508398 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.0050829 |
| MAL | mal, T-cell differentiation protein | -0.00507487 |
| TFF1 | trefoil factor 1 | -0.00507062 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00506987 |
| SP110 | SP110 nuclear body protein | -0.0050682 |
| GLUL | glutamate-ammonia ligase | -0.00506555 |
| TXNL1 | thioredoxin-like 1 | -0.00504755 |
| CLDN7 | claudin 7 | -0.00504698 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.00503673 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00503041 |
