DYRK2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2|DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8445)
External Link http://www.ncbi.nlm.nih.gov/gene/8445
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12 substrates of the kinase DYRK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CRMP1 collapsin response mediator protein 1
DCX doublecortin
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
GLI2 GLI family zinc finger 2
H3F3A H3 histone, family 3A
KATNA1 katanin p60 (ATPase containing) subunit A 1
MAPT microtubule-associated protein tau
SIAH2 siah E3 ubiquitin protein ligase 2
TP53 tumor protein p53