| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dabrafenib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dabrafenib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.250474 |
| EXT1 | exostosin glycosyltransferase 1 | 0.162977 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.157888 |
| SMAD3 | SMAD family member 3 | 0.139739 |
| RNF213 | ring finger protein 213 | 0.125449 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.114915 |
| INTS6 | integrator complex subunit 6 | 0.101155 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0871787 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0855872 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0825892 |
| LCN2 | lipocalin 2 | 0.0783366 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0748818 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0704306 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0690917 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0690739 |
| FAT1 | FAT atypical cadherin 1 | 0.0682859 |
| HKDC1 | hexokinase domain containing 1 | 0.0655103 |
| DST | dystonin | 0.0637475 |
| EFNB2 | ephrin-B2 | 0.0623649 |
| PDZD8 | PDZ domain containing 8 | 0.0606856 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.060526 |
| MCU | mitochondrial calcium uniporter | 0.0592586 |
| KYNU | kynureninase | 0.0559049 |
| SERINC5 | serine incorporator 5 | 0.0557809 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.054722 |
| MYO5B | myosin VB | 0.051647 |
| IFNGR1 | interferon gamma receptor 1 | 0.0509198 |
| FNIP2 | folliculin interacting protein 2 | 0.0507693 |
| MYO1E | myosin IE | 0.050151 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0495967 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0491449 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.047953 |
| LIMA1 | LIM domain and actin binding 1 | 0.0476472 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.047084 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0468224 |
| TMC5 | transmembrane channel-like 5 | 0.046234 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0461873 |
| PLSCR2 | phospholipid scramblase 2 | 0.0456447 |
| DSPP | dentin sialophosphoprotein | 0.0431714 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0431449 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0422521 |
| DIAPH1 | diaphanous-related formin 1 | 0.0420565 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0401668 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0396246 |
| USP54 | ubiquitin specific peptidase 54 | 0.0395501 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0395059 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0392048 |
| RPL19 | ribosomal protein L19 | 0.0385402 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0382601 |
| TRIM2 | tripartite motif containing 2 | 0.0379509 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.035602 |
| SIK3 | SIK family kinase 3 | 0.0354367 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0353736 |
| SEPTIN9 | septin 9 | 0.0352651 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0351773 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0351311 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0351198 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0344864 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0342084 |
| PHF3 | PHD finger protein 3 | 0.0339898 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0338119 |
| POF1B | premature ovarian failure, 1B | 0.0334968 |
| TMEM65 | transmembrane protein 65 | 0.0334567 |
| ETV6 | ets variant 6 | 0.0328593 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0328384 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0326645 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.032218 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320749 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0317479 |
| YAP1 | Yes-associated protein 1 | 0.0308585 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0306121 |
| MLPH | melanophilin | 0.0304007 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0303073 |
| TJP1 | tight junction protein 1 | 0.0301668 |
| MX1 | MX dynamin-like GTPase 1 | 0.0299301 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0294155 |
| PERP | PERP, TP53 apoptosis effector | 0.0292607 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0292159 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0290322 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.028786 |
| DUSP10 | dual specificity phosphatase 10 | 0.0283795 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282151 |
| ARGLU1 | arginine and glutamate rich 1 | 0.02807 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0279651 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0278358 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0277734 |
| TOX3 | TOX high mobility group box family member 3 | 0.0274744 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0272679 |
| RND3 | Rho family GTPase 3 | 0.0271673 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0271423 |
| SFTPA2 | surfactant protein A2 | 0.0270959 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0270188 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0269718 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.026839 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0268068 |
| DUSP16 | dual specificity phosphatase 16 | 0.0267852 |
| CTSB | cathepsin B | 0.0264773 |
| ANXA2 | annexin A2 | 0.026278 |
| RPL7 | ribosomal protein L7 | 0.0261819 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0259289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.141169 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.124545 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.11847 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0916181 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0903806 |
| PTMA | prothymosin, alpha | -0.083164 |
| HLA-B | major histocompatibility complex, class I, B | -0.0764572 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0746498 |
| TXNIP | thioredoxin interacting protein | -0.0717319 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.071676 |
| H1-0 | H1.0 linker histone | -0.0705312 |
| LYZ | lysozyme | -0.0626192 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0611345 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0562411 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0553723 |
| EGR1 | early growth response 1 | -0.0545852 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.051154 |
| ITGA6 | integrin, alpha 6 | -0.0509767 |
| PTEN | phosphatase and tensin homolog | -0.0481165 |
| CCNL1 | cyclin L1 | -0.0474488 |
| RNF149 | ring finger protein 149 | -0.0470188 |
| RBM39 | RNA binding motif protein 39 | -0.0467776 |
| WDR45B | WD repeat domain 45B | -0.0460981 |
| EZR | ezrin | -0.0456185 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0436077 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0427098 |
| NDRG1 | N-myc downstream regulated 1 | -0.0424259 |
| XAF1 | XIAP associated factor 1 | -0.0423924 |
| DIAPH3 | diaphanous-related formin 3 | -0.0414233 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.040918 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0407891 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0405782 |
| RPS6 | ribosomal protein S6 | -0.0401709 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0397455 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0388837 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0388479 |
| RPL35A | ribosomal protein L35a | -0.0386545 |
| RUNX1 | runt-related transcription factor 1 | -0.0377914 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.037038 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0362408 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0342803 |
| NPSR1 | neuropeptide S receptor 1 | -0.0339777 |
| MKI67 | marker of proliferation Ki-67 | -0.0336661 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0335059 |
| RNF43 | ring finger protein 43 | -0.0334907 |
| GNAS | GNAS complex locus | -0.0334876 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0328891 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0327011 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0326737 |
| AHI1 | Abelson helper integration site 1 | -0.0326208 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0324108 |
| BRCA2 | breast cancer 2, early onset | -0.0323915 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0323118 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0322814 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0322407 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0318267 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0316999 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0316562 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0316283 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0314745 |
| TMSB10 | thymosin beta 10 | -0.0311503 |
| AHNAK | AHNAK nucleoprotein | -0.0306086 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0302105 |
| TPM4 | tropomyosin 4 | -0.030109 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0293762 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0293422 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0291215 |
| GOLGA4 | golgin A4 | -0.0290817 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0289966 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0289547 |
| NF1 | neurofibromin 1 | -0.0289477 |
| TNS4 | tensin 4 | -0.0287802 |
| MORF4L2 | mortality factor 4 like 2 | -0.0286801 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0286689 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0286567 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0285921 |
| RPL34 | ribosomal protein L34 | -0.0280024 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0279859 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0278644 |
| TAOK3 | TAO kinase 3 | -0.0274494 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0273064 |
| RAD51B | RAD51 paralog B | -0.0271368 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0271337 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0269848 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0269507 |
| HMGB1 | high mobility group box 1 | -0.0267607 |
| H3-3B | H3.3 histone B | -0.0267522 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0267408 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0267009 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0266268 |
| SQSTM1 | sequestosome 1 | -0.0265719 |
| USP3 | ubiquitin specific peptidase 3 | -0.0264254 |
| CALU | calumenin | -0.0262969 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0256316 |
| WASF2 | WAS protein family, member 2 | -0.0256191 |
| FOSL1 | FOS-like antigen 1 | -0.0255379 |
| RPS24 | ribosomal protein S24 | -0.0253322 |
| MXD1 | MAX dimerization protein 1 | -0.0250016 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0247129 |
| SBF2 | SET binding factor 2 | -0.0246993 |
