| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dabrafenib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dabrafenib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.156642 |
| MTSS1 | metastasis suppressor 1 | 0.12366 |
| RPS8 | ribosomal protein S8 | 0.12123 |
| MT2A | metallothionein 2A | 0.116715 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.111306 |
| STC1 | stanniocalcin 1 | 0.108581 |
| RPL19 | ribosomal protein L19 | 0.100564 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0997849 |
| RAI14 | retinoic acid induced 14 | 0.0984242 |
| LAMC2 | laminin, gamma 2 | 0.0979545 |
| HLA-E | major histocompatibility complex, class I, E | 0.0979321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0971193 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0917216 |
| LMO7 | LIM domain 7 | 0.0889391 |
| B2M | beta-2-microglobulin | 0.0867739 |
| RPL11 | ribosomal protein L11 | 0.0810449 |
| PLEC | plectin | 0.0806216 |
| RPS12 | ribosomal protein S12 | 0.0803844 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0791866 |
| RPL37 | ribosomal protein L37 | 0.0778346 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0737308 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0732777 |
| RPS6 | ribosomal protein S6 | 0.0718598 |
| CD44 | CD44 molecule (Indian blood group) | 0.068472 |
| LDHA | lactate dehydrogenase A | 0.0659916 |
| PODXL | podocalyxin-like | 0.0635991 |
| RPL37A | ribosomal protein L37a | 0.0635626 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0621643 |
| RASAL2 | RAS protein activator like 2 | 0.0615252 |
| FTL | ferritin, light polypeptide | 0.0607407 |
| RPS25 | ribosomal protein S25 | 0.060562 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.059843 |
| RPL7 | ribosomal protein L7 | 0.0596245 |
| TMSB4X | thymosin beta 4, X-linked | 0.0591583 |
| RPS3 | ribosomal protein S3 | 0.0586998 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0571771 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0561465 |
| MYO10 | myosin X | 0.0530561 |
| SLC35F3 | solute carrier family 35, member F3 | 0.05281 |
| RPL12 | ribosomal protein L12 | 0.0527495 |
| RPS27 | ribosomal protein S27 | 0.0512776 |
| CSTB | cystatin B (stefin B) | 0.051193 |
| RPLP1 | ribosomal protein, large, P1 | 0.0506303 |
| RPL30 | ribosomal protein L30 | 0.0500114 |
| PYGL | phosphorylase, glycogen, liver | 0.0499305 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0493921 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0491261 |
| CALB1 | calbindin 1, 28kDa | 0.049019 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0487918 |
| SIK3 | SIK family kinase 3 | 0.0485899 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0479827 |
| RPL26 | ribosomal protein L26 | 0.047949 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0469763 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0468819 |
| RACK1 | receptor for activated C kinase 1 | 0.0464667 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0463634 |
| TGM2 | transglutaminase 2 | 0.0455473 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0450779 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0449472 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0447535 |
| FAM107B | family with sequence similarity 107, member B | 0.0444942 |
| TXNIP | thioredoxin interacting protein | 0.0444648 |
| MT1E | metallothionein 1E | 0.0443797 |
| AMOTL1 | angiomotin like 1 | 0.0439573 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0439393 |
| RPS13 | ribosomal protein S13 | 0.0431935 |
| CDCP1 | CUB domain containing protein 1 | 0.0422811 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0415695 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0415134 |
| RPL31 | ribosomal protein L31 | 0.0412298 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.041066 |
| RPLP2 | ribosomal protein, large, P2 | 0.0408333 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0405869 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0405564 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0403972 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0402714 |
| RPLP0 | ribosomal protein, large, P0 | 0.0401923 |
| RPS17 | ribosomal protein S17 | 0.0401343 |
| RPS4X | ribosomal protein S4, X-linked | 0.0398855 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0398572 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0394558 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.03916 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0388109 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0387213 |
| RPL5 | ribosomal protein L5 | 0.0386001 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.038411 |
| DSTN | destrin (actin depolymerizing factor) | 0.0383602 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0381896 |
| TPM3 | tropomyosin 3 | 0.0381121 |
| RNF217 | ring finger protein 217 | 0.0380621 |
| RND3 | Rho family GTPase 3 | 0.0379609 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0375694 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0365565 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0363129 |
| HMGA2 | high mobility group AT-hook 2 | 0.0357175 |
| ANXA1 | annexin A1 | 0.0353442 |
| RPL35A | ribosomal protein L35a | 0.035173 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0350765 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0343231 |
| ANKRD11 | ankyrin repeat domain 11 | 0.034309 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.178983 |
| SULF1 | sulfatase 1 | -0.116867 |
| AHNAK | AHNAK nucleoprotein | -0.115322 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0948984 |
| FOXO1 | forkhead box O1 | -0.0759231 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0756148 |
| PRELID2 | PRELI domain containing 2 | -0.0699508 |
| RBM39 | RNA binding motif protein 39 | -0.0641714 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0607325 |
| MYOF | myoferlin | -0.0586313 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0580917 |
| NEK7 | NIMA-related kinase 7 | -0.0538413 |
| FLNB | filamin B, beta | -0.0512669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.051153 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0480749 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0479544 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0450269 |
| VCL | vinculin | -0.0447004 |
| MEF2A | myocyte enhancer factor 2A | -0.0445415 |
| MECOM | MDS1 and EVI1 complex locus | -0.0433939 |
| H1-0 | H1.0 linker histone | -0.0433412 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0424144 |
| POTEF | POTE ankyrin domain family, member F | -0.0422183 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0390101 |
| UBC | ubiquitin C | -0.0385796 |
| KIAA1217 | KIAA1217 | -0.0381804 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0377576 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0376 |
| NRG1 | neuregulin 1 | -0.0360752 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0360499 |
| METTL15 | methyltransferase like 15 | -0.0356129 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0349335 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0346294 |
| PALLD | palladin, cytoskeletal associated protein | -0.0341031 |
| C4BPB | complement component 4 binding protein, beta | -0.0339008 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0338471 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0333986 |
| ANLN | anillin, actin binding protein | -0.0327638 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0325443 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0324498 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0320009 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0319779 |
| EMP1 | epithelial membrane protein 1 | -0.0319226 |
| LDLR | low density lipoprotein receptor | -0.0317161 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0304252 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0295829 |
| FN1 | fibronectin 1 | -0.0291252 |
| BCL2L1 | BCL2-like 1 | -0.0289939 |
| FOXP1 | forkhead box P1 | -0.0289626 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.028745 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0283864 |
| VMP1 | vacuole membrane protein 1 | -0.0283734 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0282177 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0273705 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0270961 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0270437 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.027001 |
| NF1 | neurofibromin 1 | -0.0266121 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0259688 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0258772 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0257579 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0257266 |
| DIAPH3 | diaphanous-related formin 3 | -0.0255341 |
| SMYD3 | SET and MYND domain containing 3 | -0.0254993 |
| OGA | O-GlcNAcase | -0.0253745 |
| PLAC8 | placenta-specific 8 | -0.0253588 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0247967 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0247508 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0247211 |
| CUL4B | cullin 4B | -0.024675 |
| YBX3 | Y box binding protein 3 | -0.0242834 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0242155 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0237464 |
| ZNF217 | zinc finger protein 217 | -0.0236263 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0235036 |
| EGR1 | early growth response 1 | -0.0231074 |
| OSMR | oncostatin M receptor | -0.0227218 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0226654 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0225798 |
| CLIC4 | chloride intracellular channel 4 | -0.0220473 |
| MORF4L2 | mortality factor 4 like 2 | -0.0219014 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0218237 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0217719 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0213895 |
| NBEAL1 | neurobeachin-like 1 | -0.0211264 |
| SBF2 | SET binding factor 2 | -0.0210838 |
| MEIS2 | Meis homeobox 2 | -0.0209073 |
| PLAT | plasminogen activator, tissue | -0.0208899 |
| CRACDL | CRACD like | -0.0207757 |
| CALU | calumenin | -0.0206908 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0205969 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0204936 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -0.020457 |
| SERINC3 | serine incorporator 3 | -0.0203103 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0202584 |
| EXOC6B | exocyst complex component 6B | -0.020225 |
| LAMA5 | laminin, alpha 5 | -0.0200761 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0197876 |
| PER3 | period circadian clock 3 | -0.0197325 |
| DNAJC18 | DnaJ (Hsp40) homolog, subfamily C, member 18 | -0.0197242 |
