Dacarbazine Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma. (Chemical Entities of Biological Interest Ontology, CHEBI_4305)
External Link http://www.drugbank.ca/drugs/DB00851
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Genes

4 interacting proteins for the Dacarbazine drug from the curated DrugBank Drug Targets dataset.

Symbol Name
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
PGD phosphogluconate dehydrogenase
POLA2 polymerase (DNA directed), alpha 2, accessory subunit