Dacarbazine Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma. (Chemical Entities of Biological Interest Ontology, CHEBI_4305)
External Link http://www.hmdb.ca/metabolites/HMDB14989
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Genes

5 interacting proteins for the Dacarbazine metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
PGD phosphogluconate dehydrogenase
POLA2 polymerase (DNA directed), alpha 2, accessory subunit